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  1. Patients with chronic hepatitis C virus (HCV) experience reduced quality of life, HCV-associated symptoms, comorbid conditions, and treatment side effects. The Cognitive Behavioral Coping Skills group interven...

    Authors: Donna M. Evon, Carol E. Golin, Rachel Ruffin, Shauna Ayres and Michael W. Fried
    Citation: Pilot and Feasibility Studies 2018 4:92
  2. Anorexia nervosa (AN) is a severe psychiatric condition characterized by low body weight, fear of weight gain/becoming fat and/or behavior that interferes with weight gain, and body disturbance. Though there h...

    Authors: C. Alix Timko, Tiffanie J. Goulazian, Kathleen Kara Fitzpatrick and Daniel Rodriguez
    Citation: Pilot and Feasibility Studies 2018 4:87
  3. In the UK and beyond, public funding is used to commission interventions delivered in public health early years settings aimed at improving health and well-being and reducing inequalities in order to promote s...

    Authors: Maria Bryant, Wendy Burton, Michelle Collinson, Suzanne Hartley, Sandy Tubeuf, Kim Roberts, Annemijn E. C. Sondaal and Amanda J. Farrin
    Citation: Pilot and Feasibility Studies 2018 4:118
  4. Levels of physical activity decline with age. Some of the most disadvantaged individuals in society, such as those from lower socio-economic position, are also the most inactive. Increasing physical activity l...

    Authors: Mark A. Tully, Conor Cunningham, Margaret E. Cupples, Duane Farrell, Wendy Hardeman, Ruth F. Hunter, Bob Laventure, Suzanne M. McDonough, Joanne Morgan, Marie H. Murphy, Ellen E. A. Simpson, Catrine Tudor-Locke, Ashlene Wright and Frank Kee
    Citation: Pilot and Feasibility Studies 2018 4:117
  5. Multimorbidity, polypharmacy, and older age predispose seniors to adverse drug events (ADE). Seniors with an ADE experience greater morbidity, mortality, and health care utilization compared to their younger c...

    Authors: Joanne Man-Wai Ho, Jennifer Tung, Janine Maitland, Derelie Mangin, Lehana Thabane, J. Michael Pavlin, Jeffrey Alfonsi, Anne Holbrook, Sharon Straus and Sophiya Benjamin
    Citation: Pilot and Feasibility Studies 2018 4:116
  6. Maternal mental health conditions are prevalent across the world. For women, the perinatal period is associated with increased rates of depression and anxiety. At the same time, there is widespread documentati...

    Authors: Caprice Knapp, Simone Honikman, Michael Wirsching, Gidah Husni-Pascha and Eva Hänselmann
    Citation: Pilot and Feasibility Studies 2018 4:101
  7. Acute respiratory failure (ARF) is a common and life-threatening medical emergency. Standard prehospital management involves controlled oxygen therapy and disease-specific ancillary treatments. Continuous posi...

    Authors: Gordon W. Fuller, Steve Goodacre, Samuel Keating, Gavin Perkins, Matthew Ward, Andy Rosser, Imogen Gunson, Joshua Miller, Mike Bradburn, Praveen Thokala, Tim Harris, Andrew Carson, Maggie Marsh and Cindy Cooper
    Citation: Pilot and Feasibility Studies 2018 4:86
  8. One third of women experience intimate partner violence (IPV) in their lifetime. Orthopaedic health care professionals are in a good position to identify women experiencing escalating physical violence and act...

    Authors: Kim Madden
    Citation: Pilot and Feasibility Studies 2018 4:115
  9. The harmful use of alcohol is a causal factor in more than 200 disease and injury conditions and leads to over 3 million deaths every year worldwide. Relatively few problem alcohol users access treatment due t...

    Authors: Fiona L. Hamilton, Jo Hornby, Jessica Sheringham, Stuart Linke, Charlotte Ashton, Kevin Moore, Fiona Stevenson and Elizabeth Murray
    Citation: Pilot and Feasibility Studies 2018 4:114
  10. State health agencies (SHA) and local health agencies (LHA) face several challenges with the dissemination of local health data using Web-Based Data Query Systems (WDQS). To help guide future research, this st...

    Authors: Manik Ahuja, Robert Aseltine, Nicholas Warren, Susan Reisine, Pam Holtzclaw Williams and Andy Cislo
    Citation: Pilot and Feasibility Studies 2018 4:113
  11. We used various methods for identifying and prioritizing patient-centered outcomes (PCOs) for comparative effectiveness research (CER).

    Authors: Evan Mayo-Wilson, Asieh Golozar, Terrie Cowley, Nicole Fusco, Gillian Gresham, Jennifer Haythornthwaite, Elizabeth Tolbert, Jennifer L. Payne, Lori Rosman, Susan Hutfless, Joseph K. Canner and Kay Dickersin
    Citation: Pilot and Feasibility Studies 2018 4:95
  12. Despite medical advances, major surgery remains high risk. Up to 44% of patients experience postoperative complications, which can have huge impacts for patients and the healthcare system. Early recognition of...

    Authors: C. L. Downey, J. Croft, H. Buckley, R. Randell, J. M. Brown and D. G. Jayne
    Citation: Pilot and Feasibility Studies 2018 4:112
  13. Fatigue is rated as the most distressing side effect of radiotherapy treatment for curable breast cancer. About four in ten women treated experience fatigue, which can last for years after treatment. The impac...

    Authors: N. Courtier, S. Gaze, J. Armes, A. Smith, L. Radley, J. Armytage, M. Simmonds, A. Johnson, T. Gambling and J. Hopkinson
    Citation: Pilot and Feasibility Studies 2018 4:85
  14. Research estimates that 30% of children under the age of 16 years in the UK live with at least one parent with an alcohol use disorder (AUD). Parental AUDs are associated with adverse childhood experiences and...

    Authors: Ruth McGovern, Elaine Stamp, Mehdi Javanbakht, Elaine McColl, Matthew Hickman and Eileen Kaner
    Citation: Pilot and Feasibility Studies 2018 4:111
  15. Socially disadvantaged men are at high risk of suffering from alcohol-related harm. Disadvantaged groups are less likely to engage with health promotion. There is a need for interventions that reach large numb...

    Authors: Linda Irvine, Ambrose J. Melson, Brian Williams, Falko F. Sniehotta, Gerry Humphris and Iain K. Crombie
    Citation: Pilot and Feasibility Studies 2018 4:105
  16. An estimated 17,000 patients are treated annually in the UK with radical radiotherapy (RT) for pelvic cancer. New treatment approaches in RT have increased survivorship and changed the subjective toxicity prof...

    Authors: Patricia Holch, Simon Pini, Ann M. Henry, Susan Davidson, Jacki Routledge, Julia Brown, Kate Absolom, Alexandra Gilbert, Kevin Franks, Claire Hulme, Carolyn Morris and Galina Velikova
    Citation: Pilot and Feasibility Studies 2018 4:110
  17. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in children, and currently, there are no FDA-approved therapies. Plasminogen activator inhibitor-1 (PAI-1) is elevated in children with...

    Authors: Miriam B. Vos, Ran Jin, Juna V. Konomi, Rebecca Cleeton, Jessica Cruz, Saul Karpen, Dellys Soler Rodriguez, Jennifer K. Frediani, Courtney McCracken and Jean Welsh
    Citation: Pilot and Feasibility Studies 2018 4:109
  18. Worldwide caesarean section (CS) delivery is the most common major operation. Approximately 25% of pregnant women undergo a CS in the UK for delivery of their babies. Sepsis and post-natal infection constitute...

    Authors: V. Hodgetts Morton, A. Wilson, C. Hewitt, A. Weckesser, N. Farmer, D. Lissauer, P. Hardy and R. K. Morris
    Citation: Pilot and Feasibility Studies 2018 4:84
  19. Physical activity (PA) programmes effective under ‘research’ conditions may not be effective under ‘real-world’ conditions. A potential solution is to refer patients to existing PA community-based PA services.

    Authors: Gill Hubbard, Anna Campbell, Abi Fisher, Michelle Harvie, Wendy Maltinsky, Russell Mullen, Elspeth Banks, Jackie Gracey, Trish Gorely, Julie Munro and Gozde Ozakinci
    Citation: Pilot and Feasibility Studies 2018 4:108
  20. Pilot trials are miniature researches carried out with the sole aim of acting as the precursor for larger more definitive studies. Abstracts are used to summarize and introduce the findings to the reading audi...

    Authors: Godsent C. Isiguzo, Moleen Zunza, Maxwell Chirehwa, Bongani M. Mayosi and Lehana Thabane
    Citation: Pilot and Feasibility Studies 2018 4:107
  21. Although supported self-management is a well-recognised part of chronic disease management, it has not been routinely used as part of healthcare for adults with a learning disability. We developed an intervent...

    Authors: Allan House, Gary Latchford, Amy M. Russell, Louise Bryant, Judy Wright, Elizabeth Graham, Alison Stansfield and Ramzi Ajjan
    Citation: Pilot and Feasibility Studies 2018 4:106
  22. Evaluations of complex interventions in public health are frequently undermined by problems that can be identified before the effectiveness study stage. Exploratory studies, often termed pilot and feasibility ...

    Authors: Britt Hallingberg, Ruth Turley, Jeremy Segrott, Daniel Wight, Peter Craig, Laurence Moore, Simon Murphy, Michael Robling, Sharon Anne Simpson and Graham Moore
    Citation: Pilot and Feasibility Studies 2018 4:104
  23. Sedentary behaviour (sitting) is a highly prevalent negative health behaviour, with individuals of all ages exposed to environments that promote prolonged sitting. Excessive sedentary behaviour adversely affec...

    Authors: Stacy A. Clemes, Daniel D. Bingham, Natalie Pearson, Yu-Ling Chen, Charlotte Edwardson, Rosemary McEachan, Keith Tolfrey, Lorraine Cale, Gerry Richardson, Mike Fray, Stephan Bandelow, Nishal Bhupendra Jaicim, Jo Salmon, David Dunstan and Sally E. Barber
    Citation: Pilot and Feasibility Studies 2018 4:103
  24. Since the introduction of the Teenage Pregnancy Strategy (TPS), England’s under-18 conception rate has fallen by 55%, but a continued focus on prevention is needed to maintain and accelerate progress. The teen...

    Authors: Ruth Ponsford, Elizabeth Allen, Rona Campbell, Diana Elbourne, Alison Hadley, Maria Lohan, G. J. Melendez-Torres, Catherine H. Mercer, Steve Morris, Honor Young and Chris Bonell
    Citation: Pilot and Feasibility Studies 2018 4:102
  25. Botulinum toxin-A is provided for adults with post-stroke spasticity. Following injection, there is a variation in the rehabilitation therapy type and amount provided. The purpose of this study was to determin...

    Authors: Natasha A. Lannin, Louise Ada, Tamina Levy, Coralie English, Julie Ratcliffe, Doungkamol Sindhusake and Maria Crotty
    Citation: Pilot and Feasibility Studies 2018 4:82
  26. The HOMEONE study is part of the larger HOME project, which aims to provide evidence of diagnostic and therapeutic yield (“change of management”) of a patient-controlled portable EEG device with dry electrodes fo...

    Authors: Thomas Neumann, Anne Katrin Baum, Ulrike Baum, Renate Deike, Helmut Feistner, Hermann Hinrichs, Joseph Stokes and Bernt-Peter Robra
    Citation: Pilot and Feasibility Studies 2018 4:100
  27. Remote biomonitoring of vital parameters in hospitals and homes has the potential to improve coverage and quality of maternal and neonatal health. Wearable sensors coupled with modern information and communica...

    Authors: Suman Rao, Prashanth Thankachan, Bharadwaj Amrutur, Maryann Washington and Prem K. Mony
    Citation: Pilot and Feasibility Studies 2018 4:99
  28. Pulmonary arterial hypertension (PAH) is an uncommon condition with progressive heart failure and premature death. Treatment costs up to £120,000 per patient per year, and the psychological burden of PAH is su...

    Authors: R. M. R. Tulloh, V. Garratt, J. Tagney, J. Turner-Cobb, E. Marques, R. Greenwood, L. Howard, W. Gin-Sing, A. Barton, P. Ewings, P. Craggs and W. Hollingworth
    Citation: Pilot and Feasibility Studies 2018 4:78
  29. Increasing importance is being placed on optimizing the role of Nursing Aides (NAs) in improving quality of care for nursing home (NH) residents. One approach to do so is to have NAs participate in assessments...

    Authors: Veronique M. Boscart, George Heckman, Meaghan Davey, Michelle Heyer and John P. Hirdes
    Citation: Pilot and Feasibility Studies 2018 4:77
  30. Health economic evaluations rely on the accurate measurement of health service resource use in order to calculate costs. These are usually measured with patient completed questionnaires using instruments such ...

    Authors: Nefyn H. Williams, Kevin Mawdesley, Jessica L. Roberts, Nafees Ud Din, Nicola Totton, Joanna M. Charles, Zoe Hoare and Rhiannon T. Edwards
    Citation: Pilot and Feasibility Studies 2018 4:76
  31. Falls are an emerging public health issue in India, with the impact set to rise as the population ages. We sought to evaluate the acceptability, feasibility and likely impact of a yoga-based program aimed at i...

    Authors: Lisa Keay, Devarsetty Praveen, Abdul Salam, K. V. Rajasekhar, Anne Tiedemann, Vimala Thomas, Jagnoor Jagnoor, Cathie Sherrington and Rebecca Q. Ivers
    Citation: Pilot and Feasibility Studies 2018 4:74
  32. Endometriosis affects 6–10% of women and is associated with debilitating pelvic pain. It costs the UK > £2.8 billion per year in loss of productivity. Endometriosis can be managed by surgical excision or medic...

    Authors: Ibtisam M. Abokhrais, Philippa T. K. Saunders, Fiona C. Denison, Ann Doust, Linda Williams and Andrew W. Horne
    Citation: Pilot and Feasibility Studies 2018 4:83
  33. A deterioration in mental health and admission to an acute mental health unit can result in skill loss and decreased participation in daily life. Furthermore, discharge from hospital is associated with high ri...

    Authors: Mary Birken, Claire Henderson and Mike Slade
    Citation: Pilot and Feasibility Studies 2018 4:81
  34. The challenges of conducting research with hard to reach vulnerable groups are particularly pertinent for people with learning disabilities. Data collection methods for previous cost and cost-effectiveness ana...

    Authors: John L. O’Dwyer, Amy M. Russell, Louise D. Bryant, Rebecca E. A. Walwyn, Alexandra M. Wright-Hughes, Elizabeth H. Graham, Judy M. Wright, Shaista Meer, Jacqueline Birtwistle, Amanda J. Farrin, Allan O. House and Claire T. Hulme
    Citation: Pilot and Feasibility Studies 2018 4:80
  35. Acute respiratory infections (ARIs), caused by the high level of immaturity of the immune system, are a major cause of morbidity in preterm newborns. The probiotic Escherichia coli strain Nissle 1917 (EcN) is wel...

    Authors: Mykola L. Aryayev, Liudmyla I. Senkivska, Nataliya K. Bredeleva and Irina V. Talashova
    Citation: Pilot and Feasibility Studies 2018 4:79
  36. Eating disorders are serious psychiatric illnesses that are often associated with poor quality of life and low long-term recovery rates. Peer mentor programs have been found to improve psychiatric symptoms and...

    Authors: Jennifer Beveridge, Andrea Phillipou, Kelly Edwards, Alice Hobday, Krissy Hilton, Cathy Wyett, Anna Saw, Georgia Graham, David Castle, Leah Brennan, Philippa Harrison, Rebecca de Gier, Narelle Warren, Freya Hanly, Benjamin Torrens-Witherow and J. Richard Newton
    Citation: Pilot and Feasibility Studies 2018 4:75
  37. Patellofemoral pain (PFP) is the most common knee condition among adolescents, with a prevalence of 6–7% resulting in reduced function and quality of life. Exercise therapy is recommended for treating PFP, but...

    Authors: Michael S. Rathleff, Camilla R. Rathleff, Sinead Holden, Kristian Thorborg and Jens L. Olesen
    Citation: Pilot and Feasibility Studies 2018 4:73
  38. Efficacy of acupuncture is difficult to demonstrate without a feasible double-blind milieu. Double-blind acupuncture needles have been validated in single session protocols with one or two needles but not been...

    Authors: Judith M. Schlaeger, Nobuari Takakura, Hiroyoshi Yajima, Miho Takayama, Alana D. Steffen, Elizabeth M. Gabzdyl, Robyn A. Nisi, Kathleen McGowan Gruber, Jason M. Bussell and Diana J. Wilkie
    Citation: Pilot and Feasibility Studies 2018 4:72
  39. Hypertension is the most common modifiable risk factor for cardiovascular disease, with an increasing prevalence with age, but with easily available medications to control it. Adverse effects of these medicati...

    Authors: Marcel Ruzicka, Brendan McCormick, Peter Magner, Tim Ramsay, Cedric Edwards, Ann Bugeja and Swapnil Hiremath
    Citation: Pilot and Feasibility Studies 2018 4:71
  40. Patellofemoral joint (PFJ) osteoarthritis (OA) is prevalent in middle-aged and older adults. Despite this, there are minimal studies which have examined conservative interventions for PFJ OA. Weakness of proxi...

    Authors: Lisa T. Hoglund, Laura Pontiggia and John D. Kelly IV
    Citation: Pilot and Feasibility Studies 2018 4:70
  41. Experimentation is a natural part of adolescent maturation. In conjunction with increased exposure to behaviours such as alcohol or substance use, and the potentially intensified influence of peer groups, unhe...

    Authors: Jan Pringle, Lawrence Doi, Divya Jindal-Snape, Ruth Jepson and John McAteer
    Citation: Pilot and Feasibility Studies 2018 4:69
  42. Parental supervised brushing (PSB) when initiated in infancy can lead to long-term protective home-based oral health habits thereby reducing the risk of dental caries. However, PSB is a complex behaviour with ...

    Authors: Ieva Eskyte, Kara Gray-Burrows, Jenny Owen, Bianca Sykes-Muskett, Tim Zoltie, Susanne Gill, Victoria Smith, Rosemary McEachan, Zoe Marshman, Robert West, Sue Pavitt and Peter Day
    Citation: Pilot and Feasibility Studies 2018 4:68
  43. INVESTIGATE-I (INVasive Evaluation before Surgical Treatment of Incontinence Gives Added Therapeutic Effect?) was a mixed methods study to assess the feasibility of a future randomised controlled trial of inva...

    Authors: Tara Homer, Jing Shen, Luke Vale, Elaine McColl, Douglas G. Tincello and Paul Hilton
    Citation: Pilot and Feasibility Studies 2018 4:67
  44. The most common physical deficit caused by a stroke is muscle weakness which limits a person’s mobility. Mobility encompasses activities necessary for daily functioning: getting in and out bed, on/off toilet, ...

    Authors: Angie Logan, Jennifer Freeman, Bridie Kent, Jillian Pooler, Siobhan Creanor, Jane Vickery, Doyo Enki, Andrew Barton and Jonathan Marsden
    Citation: Pilot and Feasibility Studies 2018 4:66
  45. Electronic patient-reported outcomes (e-PROs) may provide valid and feasible options for obtaining family input on their child’s functioning for care planning and outcome monitoring, but they have not been ado...

    Authors: Mary A. Khetani, Beth M. McManus, Kristen Arestad, Zachary Richardson, Renee Charlifue-Smith, Cordelia Rosenberg and Briana Rigau
    Citation: Pilot and Feasibility Studies 2018 4:65
  46. Sepsis is a common condition which kills between 36,000 and 64,000 people every year in the UK. Early recognition and management of sepsis has been shown to reduce mortality and improve the health and well-bei...

    Authors: Chris Moore, Jenna Bulger, Matt Morgan, Timothy Driscoll, Alison Porter, Saiful Islam, Mike Smyth, Gavin Perkins, Bernadette Sewell, Timothy Rainer, Prabath Nanayakkara, Chukwudi Okolie, Susan Allen, Greg Fegan, Jan Davies, Theresa Foster…
    Citation: Pilot and Feasibility Studies 2018 4:64
  47. Condoms remain the main protection against sexually transmitted infections (STIs) when used correctly and consistently. Yet, there are many reported barriers to their use such as negative attitudes, reduced se...

    Authors: Nicole Stone, Cynthia Graham, Sydney Anstee, Katherine Brown, Katie Newby and Roger Ingham
    Citation: Pilot and Feasibility Studies 2018 4:63
  48. Robotic wearable exoskeletons have been utilized as a gait training device in persons with spinal cord injury. This pilot study investigated the feasibility of offering exoskeleton-assisted gait training (EGT)...

    Authors: Shuo-Hsiu Chang, Taimoor Afzal, Jeffrey Berliner and Gerard E. Francisco
    Citation: Pilot and Feasibility Studies 2018 4:62
  49. Attention deficit hyperactivity disorder (ADHD) is a common and growing problem and a leading cause of child referrals to Child and Adult Mental Health Services (CAMHS). It is a drain on resources across natio...

    Authors: Philippa Fibert, Clare Relton, Tessa Peasgood and David Daley
    Citation: Pilot and Feasibility Studies 2018 4:61
  50. It is important to be able to reliably and feasibly measure infant and toddler physical activity in order to determine adherence to current physical activity guidelines and effects on early life development, g...

    Authors: Alessandra Prioreschi, Thomas Nappey, Kate Westgate, Patrick Olivier, Soren Brage and Lisa Kim Micklesfield
    Citation: Pilot and Feasibility Studies 2018 4:60

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