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  1. Research

    A pilot investigation to optimise methods for a future satiety preload study

    Preload studies are used to investigate the satiating effects of foods and food ingredients. However, the design of preload studies is complex, with many methodological considerations influencing appetite resp...

    Mark R. Hobden, Laetitia Guérin-Deremaux, Daniel M. Commane, Ian Rowland, Glenn R. Gibson and Orla B. Kennedy

    Pilot and Feasibility Studies 2017 3:61

    Published on: 17 November 2017

  2. Research

    Evaluation of neurological changes in secondary progressive multiple sclerosis patients treated with immune modulator MIS416: results from a feasibility study

    While disease progression can be readily monitored in early stage relapsing multiple sclerosis (MS), it is more challenging for secondary progressive multiple sclerosis (SPMS). This advanced stage of disease h...

    Gill A. Webster, Dalice A. Sim, Anne C. La Flamme and Nancy E. Mayo

    Pilot and Feasibility Studies 2017 3:60

    Published on: 16 November 2017

  3. Study Protocol

    The use of smartphones to influence lifestyle changes in overweight and obese youth with congenital heart disease: a single-arm study

    Both obesity and congenital heart disease (CHD) are risk factors for the long-term cardiovascular health of children and adolescents. The addition of smart mobile technology to conventional lifestyle counselin...

    Meghan Rombeek, Stefanie De Jesus, Luis Altamirano-Diaz, Eva Welisch, Harry Prapavessis, Jamie A. Seabrook and Kambiz Norozi

    Pilot and Feasibility Studies 2017 3:59

    Published on: 15 November 2017

  4. Study Protocol

    A comparison of isometric, isotonic concentric and isotonic eccentric exercises in the physiotherapy management of subacromial pain syndrome/rotator cuff tendinopathy: study protocol for a pilot randomised controlled trial

    Subacromial pain syndrome (SPS) involving rotator cuff tendinopathy is a common cause of shoulder pain and disability. Evidence suggests that structured physiotherapy may be as effective as surgery in this con...

    Rita Kinsella, Sallie M. Cowan, Lyn Watson and Tania Pizzari

    Pilot and Feasibility Studies 2017 3:45

    Published on: 14 November 2017

  5. Study Protocol

    An implementation-effectiveness hybrid trial of video-based family therapy for peripartum depression in home visited mothers: a protocol for a pilot trial

    The Federal Maternal, Infant, and Early Childhood Home Visiting (HV) Program serves over 100,000 vulnerable families at risk for child abuse in the USA and aims to improve many outcomes, including maternal men...

    Fallon Cluxton-Keller, Craig L. Donnelly, Melony Williams, Jennifer Buteau, Patricia Stolte, Maggie Monroe-Cassel and Martha L. Bruce

    Pilot and Feasibility Studies 2017 3:55

    Published on: 13 November 2017

  6. Research

    Unsupervised progressive elastic band exercises for frail geriatric inpatients objectively monitored by new exercise-integrated technology—a feasibility trial with an embedded qualitative study

    Frailty is a serious condition frequently present in geriatric inpatients that potentially causes serious adverse events. Strength training is acknowledged as a means of preventing or delaying frailty and loss...

    C. R. Rathleff, T. Bandholm, E. G. Spaich, M. Jorgensen and J. Andreasen

    Pilot and Feasibility Studies 2017 3:56

    Published on: 13 November 2017

  7. Study Protocol

    A phase 2 quasi-experimental trial evaluating the feasibility, acceptability, and potential effectiveness of complex nursing intervention focused on QoL assessment on advanced cancer patients with palliative care needs: study protocol

    Palliative care (PC) is an approach that improves the quality of life (QoL) of patients and their families facing the problem associated with incurable terminal disease. A number of QoL assessment tools have b...

    Gianluca Catania, Annamaria Bagnasco, Alessio Signori, Paola Pilastri, Marta Bottino, Claudia Cervetti, Milko Zanini, Giuseppe Aleo and Loredana Sasso

    Pilot and Feasibility Studies 2017 3:54

    Published on: 13 November 2017

  8. Study Protocol

    Changes of intestinal microbiota composition and diversity in very low birth weight infants related to strategies of NEC prophylaxis: protocol for an observational multicentre pilot study

    At the Division of Neonatology, Department of Paediatrics, Medical University Graz, a unique regimen of necrotizing enterocolitis (NEC) prophylaxis in preterm infants showing a < 1500 g birth weight (i.e. very...

    Stefan Kurath-Koller, Christine Moissl-Eichinger, Gregor Gorkiewicz, Raimund Kraschl, Claudia Kanduth, Barbara Hopfer, Berndt Urlesberger and Bernhard Resch

    Pilot and Feasibility Studies 2017 3:52

    Published on: 7 November 2017

  9. Research

    Ethnic differences in patients’ perceptions towards isolated orthopedic injuries: a pilot study

    Patients’ perceptions of their healthcare have been reported to influence clinical outcomes following orthopedic trauma. Findings across clinical outcomes have demonstrated significant differences in perceptio...

    Boris A. Zelle, Gurpreet Singh, Deanna L. Kitchen, Roberto J. Fajardo, Mohit Bhandari and Melissa A. Valerio

    Pilot and Feasibility Studies 2017 3:39

    Published on: 7 November 2017

  10. Methodology

    Alpha test results for a Housing First eLearning strategy: the value of multiple qualitative methods for intervention design

    Detailed descriptions of implementation strategies are lacking, and there is a corresponding dearth of information regarding methods employed in implementation strategy development. This paper describes method...

    Emily Q. Ahonen, Dennis P. Watson, Erin L. Adams and Alan McGuire

    Pilot and Feasibility Studies 2017 3:46

    Published on: 31 October 2017

  11. Methodology

    Danish translation of a physical function item bank from the Patient-Reported Outcome Measurement Information System (PROMIS)

    The Patient-Reported Outcome Measurement Information System (PROMIS) is an assessment system that aims to provide more valid, reliable, responsive, and precise patient-reported outcome (PRO) measures than has ...

    Christina W. Schnohr, Charlotte L. Rasmussen, Henning Langberg and Jakob B. Bjørner

    Pilot and Feasibility Studies 2017 3:29

    Published on: 27 October 2017

  12. Erratum

    Pilot and Feasibility Studies 2017 3:48

    Published on: 24 October 2017

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  13. Study Protocol

    Feasibility, safety, acceptability, and functional outcomes of playing Nintendo Wii Fit Plus™ for frail elderly: study protocol for a feasibility trial

    Frailty can be defined as a medical syndrome with multiple causes and contributors, characterized by diminished strength and endurance and reduced physiological function that increases the vulnerability to dev...

    Gisele Cristine Vieira Gomes, Jéssica Maria Ribeiro Bacha, Maria do Socorro Simões, Sumika Mori Lin, Larissa Alamino Pereira Viveiro, Eliana Maria Varise, Wilson Jacob Filho and José Eduardo Pompeu

    Pilot and Feasibility Studies 2017 3:41

    Published on: 24 October 2017

  14. Research

    Pilot parallel randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people: ‘STOPCUTS’

    Skin tears are common in older adults and those taking steroids and warfarin. They are traumatic, often blunt injuries caused by oblique knocks to the extremities. The epidermis may separate from the dermis or...

    Roy J. Powell, Christopher J. Hayward, Caroline L. Snelgrove, Kathleen Polverino, Linda Park, Rohan Chauhan, Philip H. Evans, Rachel Byford, Carolyn Charman, Christopher J. W. Foy, Colin Pritchard and Andrew Kingsley

    Pilot and Feasibility Studies 2017 3:43

    Published on: 17 October 2017

  15. Study Protocol

    Interpersonal art psychotherapy for the treatment of aggression in people with learning disabilities in secure care: a protocol for a randomised controlled feasibility study

    Art psychotherapy has greater potential for use with adults with mild to moderate learning disabilities as it places less of a burden on verbal interaction to achieve positive therapeutic, psychological, and b...

    Simon S. Hackett, John L. Taylor, Mark Freeston, Andrew Jahoda, Elaine McColl, Lindsay Pennington and Eileen Kaner

    Pilot and Feasibility Studies 2017 3:42

    Published on: 10 October 2017

  16. Methodology

    Optimising the acceptability and feasibility of novel complex interventions: an iterative, person-based approach to developing the UK Morita therapy outpatient protocol

    The aim of this paper is to showcase best practice in intervention development by illustrating a systematic, iterative, person-based approach to optimising intervention acceptability and feasibility, as applie...

    Holly Victoria Rose Sugg, David A. Richards and Julia Frost

    Pilot and Feasibility Studies 2017 3:37

    Published on: 3 October 2017

  17. Study Protocol

    Small volume plasma exchange for Guillain-Barré syndrome in resource poor settings: a safety and feasibility study

    In Bangladesh, most patients with Guillain-Barré syndrome (GBS) cannot afford standard treatment with intravenous immunoglobulin (IVIG) or a standard plasma exchange (PE) course, which partly explains the high...

    Md. Badrul Islam, Zhahirul Islam, Shafiqur Rahman, Hubert P. Endtz, Margreet C. Vos, Mathieu van der Jagt, Pieter A. van Doorn, Bart C. Jacobs and Quazi D. Mohammad

    Pilot and Feasibility Studies 2017 3:40

    Published on: 29 September 2017

  18. Study Protocol

    Creative music therapy to promote brain structure, function, and neurobehavioral outcomes in preterm infants: a randomized controlled pilot trial protocol

    Preterm birth is associated with increased risk of neurological impairment and deficits in cognition, motor function, and behavioral problems. Limited studies indicate that multi-sensory experiences support br...

    Friederike Barbara Haslbeck, Hans-Ulrich Bucher, Dirk Bassler and Cornelia Hagmann

    Pilot and Feasibility Studies 2017 3:36

    Published on: 26 September 2017

  19. Study Protocol

    HOPE: Help fOr People with money, employment, benefit or housing problems: study protocol for a randomised controlled trial

    Self-harm and suicide increase in times of economic recession. Factors including job loss, austerity measures, financial difficulties and house repossession contribute to the risk. Vulnerable individuals commo...

    M. C. Barnes, A. M. Haase, A. M. Bard, J. L. Donovan, R. Davies, S. Dursley, J. Potokar, N. Kapur, K. Hawton, R. C. O’Connor, W. Hollingworth, C. Metcalfe and D. Gunnell

    Pilot and Feasibility Studies 2017 3:44

    Published on: 19 September 2017

  20. Research

    A nurse-delivered mental health intervention for obstetric fistula patients in Tanzania: results of a pilot randomized controlled trial

    Obstetric fistula has severe psychological consequences, but no evidence-based interventions exist to improve mental health in this population. This pilot trial evaluated a psychological intervention for women...

    Melissa H. Watt, Mary V. Mosha, Alyssa C. Platt, Kathleen J. Sikkema, Sarah M. Wilson, Elizabeth L. Turner and Gileard G. Masenga

    Pilot and Feasibility Studies 2017 3:35

    Published on: 12 September 2017

  21. Study Protocol

    Research protocol for a complex intervention to support hearing and vision function to improve the lives of people with dementia

    Hearing and vision impairments are among the most common and disabling comorbidities in people living with dementia. Intervening to improve sensory function could be a means by which the lives of people living...

    Iracema Leroi, Annie Pye, Christopher J. Armitage, Anna Pavlina Charalambous, Fofi Constantinidou, Catherine Helmer, Ines Himmelsbach, Sarah Marié, Jahanara Miah, Suzanne Parsons, Jemma Regan, Chryssoula Thodi, Lucas Wolski, Abebaw Mengistu Yohannes and Piers Dawes

    Pilot and Feasibility Studies 2017 3:38

    Published on: 11 September 2017

  22. Research

    DIAMOND (DIgital Alcohol Management ON Demand): a mixed methods feasibility RCT and embedded process evaluation of a digital health intervention to reduce hazardous and harmful alcohol use

    Alcohol is a major risk factor for preventable illness, with huge cost to healthcare economies. There is a role for alcohol-specific digital health interventions (DHI), but there have been few randomised contr...

    Fiona L. Hamilton, Jo Hornby, Jessica Sheringham, Stuart Linke, Charlotte Ashton, Kevin Moore, Fiona Stevenson and Elizabeth Murray

    Pilot and Feasibility Studies 2017 3:34

    Published on: 21 August 2017

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