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  1. Depression impacts the lives of millions of people worldwide. Behavioral activation (BA), derived from cognitive behavioral therapy, has the potential for improving depressive symptoms in patients with depress...

    Authors: Alessia D’Elia, Monica Bawor, Brittany B. Dennis, Meha Bhatt, Kathryn Litke, Kathleen McCabe, Jeff Whattam, Laura Garrick, Laura O’Neill, Scott Simons, Sandra Chalmers, Brenda Key, Stefanie Goyert, Phillip Laplante, Meredith Vanstone, Feng Xie…

    Citation: Pilot and Feasibility Studies 2020 6:61

    Content type: Research

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  2. Physical inactivity and unhealthy eating are two leading behavioral risk factors contributing to preventable non-communicable diseases (NCDs). Evidence-based interventions (EBI) using community-engaged approac...

    Authors: Oluwakemi Ololade Odukoya, Steve Manortey, Michelle Takemoto, Steve Alder and Kolawole S. Okuyemi

    Citation: Pilot and Feasibility Studies 2020 6:59

    Content type: Study Protocol

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  3. Despite the benefits of physical activity for walking ability, balance, and mood, less than 30% of stroke survivors engage in recommended levels of physical activity with high levels of sedentary behaviour obs...

    Authors: Sarah A. Moore, Leah Avery, Christopher I. M. Price and Darren Flynn

    Citation: Pilot and Feasibility Studies 2020 6:58

    Content type: Study Protocol

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  4. There is a need for workplace programs promoting healthy eating and activity that reach low-wage employees and are scalable beyond the study site. Interventions designed with dissemination in mind aim to utili...

    Authors: Rachel G. Tabak, Jaime R. Strickland, Bridget Kirk, Ryan Colvin, Richard I. Stein, Hank Dart, Graham A. Colditz, Ann Marie Dale and Bradley A. Evanoff

    Citation: Pilot and Feasibility Studies 2020 6:57

    Content type: Research

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  5. Frailty is characterised by increased vulnerability to falls, disability, hospitalisation and care home admission. However, it is relatively reversible in the early stages. Older people living with frailty oft...

    Authors: Anne Heaven, Peter Bower, Bonnie Cundill, Amanda Farrin, Marilyn Foster, Robbie Foy, Suzanne Hartley, Rebecca Hawkins, Claire Hulme, Sara Humphrey, Rebecca Lawton, Catriona Parker, Neil Pendleton, Robert West, John Young and Andrew Clegg

    Citation: Pilot and Feasibility Studies 2020 6:56

    Content type: Study Protocol

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  6. Youth with autism spectrum disorder (ASD) represent a growing population with significant service needs. Prominent among these needs are high rates of co-occurring psychiatric conditions that contribute to inc...

    Authors: Kelsey S. Dickson, Gregory A. Aarons, Laura Gutermuth Anthony, Lauren Kenworthy, Brent R. Crandal, Katherine Williams and Lauren Brookman-Frazee

    Citation: Pilot and Feasibility Studies 2020 6:55

    Content type: Study Protocol

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  7. Most severe mental disorders have their onset between the age of 17 and 27, a time when many young adults begin participating in secondary or post-secondary education. The cognitive deficits typically associat...

    Authors: Lana K. M. Otto, Jacomijn Hofstra, Michelle G. Mullen, Derek Malenczak, Nynke Boonstra, Lisette van der Meer, Wim Veling, Cees Boerhout, Gerard D. van Rijsbergen, Jos de Vries, Boudien van der Pol, Gerdina H. M. Pijnenborg and Lies Korevaar

    Citation: Pilot and Feasibility Studies 2020 6:54

    Content type: Study Protocol

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  8. Polycystic ovary syndrome (PCOS) is a prevalent women’s health condition with reproductive, metabolic, and psychological manifestations. Weight loss can improve these symptoms and is a key goal; however, many ...

    Authors: Carolyn Ee, Caroline A. Smith, Michael Costello, Lisa Moran, Genevieve Z. Steiner, Nigel Stepto, Adele Cave, Atekah Albrehee and Helena Teede

    Citation: Pilot and Feasibility Studies 2020 6:53

    Content type: Study Protocol

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  9. There is uncertainty regarding the safety and effectiveness of direct oral anticoagulant agents in patients with antiphospholipid syndrome (APS). We performed a multicenter feasibility study to examine our abi...

    Authors: Kimberly Legault, Mark Blostein, Marc Carrier, Susan Kahn, Sam Schulman, Sudeep Shivakumar, Cynthia Wu and Mark A. Crowther

    Citation: Pilot and Feasibility Studies 2020 6:52

    Content type: Research

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    The Correction to this article has been published in Pilot and Feasibility Studies 2020 6:67

  10. Poor menstrual health and hygiene (MHH) is a globally recognised public health challenge. A pilot study of an MHH intervention was conducted in two secondary schools in Entebbe, Uganda, over 9 months. The inte...

    Authors: Ruth Nalugya, Clare Tanton, Laura Hytti, Catherine Kansiime, Kevin Nakuya, Prossy Namirembe, Shamira Nakalema, Stella Neema, Connie Alezuyo, Saidat Namuli Musoke, Belen Torondel, Suzanna C. Francis, David A. Ross, Chris Bonell, Janet Seeley and Helen A. Weiss

    Citation: Pilot and Feasibility Studies 2020 6:51

    Content type: Research

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  11. Treatment of locally advanced oesophago-gastric adenocarcinoma usually entails neo-adjuvant chemotherapy (NAC) and surgery. Surgery is associated with high morbidity and mortality. Cardiopulmonary reserve of p...

    Authors: J. Chmelo, A. W. Phillips, A. Greystoke, S. J. Charman, L. Avery, K. Hallsworth, J. Welford and R. C. F. Sinclair

    Citation: Pilot and Feasibility Studies 2020 6:50

    Content type: Study Protocol

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  12. Working in good jobs is associated with good health. High unemployment rates are reported in those disabled with musculoskeletal pain. Supported employment interventions work well for helping people with menta...

    Authors: Robert Froud, Mary Grant, Kim Burton, Jonathan Foss, David R. Ellard, Kate Seers, Deb Smith, Mariana Barillec, Shilpa Patel, Kirstie Haywood and Martin Underwood

    Citation: Pilot and Feasibility Studies 2020 6:49

    Content type: Research

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  13. The guidelines for pilot and feasibility studies were published in 2016. Little is known about the guideline adherence of TCM (traditional Chinese medicine) pilot trials or whether the guidelines can significa...

    Authors: Guowei Li, Darong Wu, Xuejiao Chen, Jie Zeng, Ziyi Li and Lehana Thabane

    Citation: Pilot and Feasibility Studies 2020 6:48

    Content type: Research

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  14. Myofascial (self-)treatments, such as foam rollers to therapeutic instruments in manual therapy, are utilized increasingly in prevention and therapy in healthy people, athletes, and patients suffering from chr...

    Authors: Patrick Weber, Christine Graf, Werner Klingler, Nadine Weber and Robert Schleip

    Citation: Pilot and Feasibility Studies 2020 6:47

    Content type: Study Protocol

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  15. We sought to evaluate the acceptability of a psychological therapy programme (Therapy for Inter-episode Mood Variability in Bipolar Disorder (ThrIVe-B)) for individuals with ongoing bipolar mood instability an...

    Authors: Kim Wright, Gemma Palmer, Mahmood Javaid, Mohammod Mostazir and Tom Lynch

    Citation: Pilot and Feasibility Studies 2020 6:46

    Content type: Research

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  16. Cameroon still has relatively high maternal mortality rate (MMR) of 596/100,000 live births. Approximately 40% of births are unattended by skilled healthcare personnel with high out-of-pocket expenditures. Poo...

    Authors: Miriam N. Nkangu, Patrick M. Okwen, Lawrence Mbuagbaw, Donald K. Weledji, Janet Hatcher Roberts and Sanni Yaya

    Citation: Pilot and Feasibility Studies 2020 6:45

    Content type: Study Protocol

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  17. Individual Placement and Support (IPS) is a model of vocational rehabilitation originally developed to help people with severe mental illness obtain and maintain employment. Work disability is common amongst p...

    Authors: Michelle M. Holmes, Sabina C. Stanescu, Catherine Linaker, Catherine Price, Nick Maguire, Simon Fraser, Cyrus Cooper and Karen Walker-Bone

    Citation: Pilot and Feasibility Studies 2020 6:44

    Content type: Research

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  18. We aimed to investigate and optimise the acceptability and usefulness of a patient leaflet about antibiotic prescribing decisions made during hospitalisation, and to explore individual patient experiences and ...

    Authors: Fiona Mowbray, Katy Sivyer, Marta Santillo, Nicola Jones, Tim E. A. Peto, A. Sarah Walker, Martin J. Llewelyn and Lucy Yardley

    Citation: Pilot and Feasibility Studies 2020 6:43

    Content type: Research

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  19. Untreated heterozygous familial hypercholesterolaemia (FH) causes high low-density lipoprotein cholesterol (LDL-C) levels and increased cardiovascular disease (CVD) risk. Despite pharmacological treatment, man...

    Authors: Fiona J. Kinnear, Julian P. Hamilton-Shield, David J. Stensel, Graham Bayly, Aidan Searle, Alice E. Thackray and Fiona E. Lithander

    Citation: Pilot and Feasibility Studies 2020 6:42

    Content type: Study Protocol

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  20. The most common management strategy for tinnitus provided in the UK audiology clinics is education and advice. This may also be combined with some form of sound therapy (e.g. digital hearing aids). While educa...

    Authors: Rachel H. Haines, Jennifer White, Garry Meakin, Wei Tan, Trish Hepburn, Paul Leighton, Chloi Theriou, David Stockdale, Christine Almey, Richard Nicholson, Deborah A. Hall and Magdalena Sereda

    Citation: Pilot and Feasibility Studies 2020 6:41

    Content type: Study Protocol

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  21. Most patients with minor stroke or transient ischemic attack (TIA) are discharged with little or no specialised follow-up. Nonetheless, these patients have a high prevalence of cognitive impairments and a cons...

    Authors: Jacob Liljehult, Stig Molsted, Tom Møller, Dorthe Overgaard, Lis Adamsen, Mary Jarden and Thomas Christensen

    Citation: Pilot and Feasibility Studies 2020 6:40

    Content type: Study Protocol

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  22. Excess gestational weight gain (GWG) in pregnant adolescents is a major public health concern. Excess GWG increases risk of pregnancy complications as well as postpartum and offspring obesity and cardiometabol...

    Authors: Lauren B. Shomaker, Lauren D. Gulley, Emma L. M. Clark, Allison M. Hilkin, Bernadette Pivarunas, Marian Tanofsky-Kraff, Kristen J. Nadeau, Linda A. Barbour, Stephen M. Scott and Jeanelle L. Sheeder

    Citation: Pilot and Feasibility Studies 2020 6:39

    Content type: Study Protocol

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  23. A thoracolumbar fracture is the most common fracture of the spinal column. Where the fracture is not obviously stable or unstable, the optimal management is uncertain. There are variations between surgeons, tr...

    Authors: Elizabeth Cook, Alison Booth, Elizabeth Coleman, Arabella Scantlebury, Catriona McDaid, Catherine Hewitt, Belen Corbacho, Amar Rangan, Joy Adamson, Arun Ranganathan, Almas Khan, Sashin Ahuja, Emma Turner, Peter May, Catherine Hilton and David J. Torgerson

    Citation: Pilot and Feasibility Studies 2020 6:38

    Content type: Study Protocol

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  24. Physical inactivity contributes to disability and falls in older adults. Falls prevention exercise (FaME) programmes improve physical activity and physical function and reduce falling rates. Improvements in ph...

    Authors: Sarah Audsley, Denise Kendrick, Pip Logan, Matthew Jones and Elizabeth Orton

    Citation: Pilot and Feasibility Studies 2020 6:37

    Content type: Research

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  25. Malnutrition is a complex and costly condition that is common among older adults in the United States (US), with up to half at risk for malnutrition. Malnutrition is associated with several non-medical (i.e., ...

    Authors: Andrea M. Morris, Jessa K. Engelberg Anderson, Brenda Schmitthenner, Aileen F. Aylward, Rayad B. Shams, Karen Hurka-Richardson and Timothy F. Platts-Mills

    Citation: Pilot and Feasibility Studies 2020 6:36

    Content type: Study Protocol

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  26. Cancer is the second leading cause of death globally. Early detection and disease management lead to a better survival rate. Consequently, discovery of novel methods in cancer early diagnosis is a field of act...

    Authors: Gaétan Chanteloup, Marine Cordonnier, Nicolas Isambert, Aurélie Bertaut, Guillaume Marcion, Carmen Garrido and Jessica Gobbo

    Citation: Pilot and Feasibility Studies 2020 6:35

    Content type: Study Protocol

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  27. Residents living and dying in long-term care (LTC) homes represent one of society’s most frail and marginalized populations of older adults, particularly those residents with advanced dementia who are often ex...

    Authors: Sharon Kaasalainen, Paulette V. Hunter, Vanina Dal Bello-Haas, Lisa Dolovich, Katherine Froggatt, Thomas Hadjistavropoulos, Maureen Markle-Reid, Jenny Ploeg, Joyce Simard, Lehana Thabane, Jenny T. van der Steen and Ladislav Volicer

    Citation: Pilot and Feasibility Studies 2020 6:34

    Content type: Research

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  28. Domestic violence and abuse (DVA) is common and destructive to health. Post-traumatic stress disorder (PTSD) is a major mental health consequence of DVA. People who have experienced DVA have specific needs, ar...

    Authors: Katherine Pitt, Gene S Feder, Alison Gregory, Claire Hawcroft, David Kessler, Alice Malpass, Sarah Millband, Richard Morris, Stan Zammit and Natalia V Lewis

    Citation: Pilot and Feasibility Studies 2020 6:33

    Content type: Study Protocol

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  29. One of the core symptoms of behavioural variant frontotemporal dementia (bvFTD) is the early loss of social cognitive abilities, which has a deteriorating impact on everyday interaction and the quality of dyad...

    Authors: Martin Berwig, Claudia Dinand, Ursula Becker and Margareta Halek

    Citation: Pilot and Feasibility Studies 2020 6:32

    Content type: Research

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  30. Stress induced by pain and anxiety is common in pediatric intensive care unit (PICU) patients. Sedation/analgesia in PICU is usually achieved through various analgesics and sedatives. Excessive use of these dr...

    Authors: Gonzalo Garcia Guerra, Ari Joffe, Cathy Sheppard, Krista Hewson, Irina A. Dinu, Allan de Caen, Hsing Jou, Lisa Hartling and Sunita Vohra

    Citation: Pilot and Feasibility Studies 2020 6:31

    Content type: Study Protocol

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  31. Although there is good evidence to support the effectiveness of cognitive behavioral therapy (CBT) for the outpatient treatment of adolescent major depressive disorder (MDD), evidence-based manuals for the inp...

    Authors: Michael Frey, Kathrin Pietsch, Laura Weninger, Matthias Brockhaus, Fabian Loy, Nathalie Claus, Petra Wagenbüchler, Selina Kornbichler, Jana Kroboth, Beatrice Georgii, Inga Wermuth, Anna Kititsina, Katharina Heiser, Gerd Schulte-Körne and Belinda Platt

    Citation: Pilot and Feasibility Studies 2020 6:30

    Content type: Research

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  32. At the McGill University Health Centre (MUHC), 10% of patients living with HIV do not return for care annually. Currently, no formal system exists to re-engage out-of-care (OOC) patients. Lost & Found, develop...

    Authors: Joseph Cox, Blake Linthwaite, Kim Engler, David Lessard, Bertrand Lebouché and Nadine Kronfli

    Citation: Pilot and Feasibility Studies 2020 6:29

    Content type: Study Protocol

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  33. Physical activity and exercise interventions to improve health frequently bring about intended effects under ideal circumstances but often fail to demonstrate benefits in real-world contexts. The aim of this s...

    Authors: Matthew Haines

    Citation: Pilot and Feasibility Studies 2020 6:28

    Content type: Research

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  34. The hospital to home transition for children with medical complexity (CMC) poses many challenges, including suboptimal communication between the hospital and medical home. Our objective was to evaluate the imp...

    Authors: Noga L. Ravid, Kayla Zamora, Roberta Rehm, Megumi Okumura, John Takayama and Sunitha Kaiser

    Citation: Pilot and Feasibility Studies 2020 6:27

    Content type: Research

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  35. Critically ill patients in the intensive care unit (ICU) are at risk for central line-associated bloodstream infection (CLABSI) with an incidence up to 6.9 per 1000 catheter days. CLABSI has a significant attr...

    Authors: Nasim Zamir, Makena Pook, Ellen McDonald and Alison E. Fox-Robichaud

    Citation: Pilot and Feasibility Studies 2020 6:26

    Content type: Study Protocol

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  36. Type 2 diabetes (T2D) is a public health pandemic disproportionately affecting low- and middle-income countries. The purpose of this formative research was to adapt evidence-based diabetes self-management educ...

    Authors: Robin Whittemore, Mireya Vilar-Compte, Soraya Burrola-Méndez, Annel Lozano-Marrufo, Roberta Delvy, Mariana Pardo-Carrillo, Selene De La Cerda, Ninfa Pena-Purcell and Rafael Pérez-Escamilla

    Citation: Pilot and Feasibility Studies 2020 6:25

    Content type: Methodology

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  37. We sought to develop and test an objective scorecard-based system for assessing and categorizing available research sites in Lassa fever-affected countries based on their preparedness and capability to host La...

    Authors: Kolawole Salami, Nathalie Imbault, Aljoscha Erlebach, Johanna Urban, Mike Zoglowek and Nadia G. Tornieporth

    Citation: Pilot and Feasibility Studies 2020 6:24

    Content type: Research

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  38. Biomarkers of placental function can potentially aid the diagnosis and prediction of pregnancy complications. This randomised controlled pilot trial assessed whether for women with reduced fetal movement (RFM)...

    Authors: Lindsay Armstrong-Buisseret, Peter J. Godolphin, Lucy Bradshaw, Eleanor Mitchell, Sam Ratcliffe, Claire Storey and Alexander E. P. Heazell

    Citation: Pilot and Feasibility Studies 2020 6:23

    Content type: Research

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  39. Parent-mediated early interventions (EI) for children with autism spectrum disorder (ASD) can result in significant improvements in children’s cognitive ability, social functioning, behavior, and adaptive skil...

    Authors: Melanie Pellecchia, Rinad S. Beidas, David S. Mandell, Carolyn C. Cannuscio, Carl J. Dunst and Aubyn C. Stahmer

    Citation: Pilot and Feasibility Studies 2020 6:22

    Content type: Study Protocol

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  40. Bariatric surgery is an effective long-term weight loss strategy yielding improvements in neurocognitive function; however, the mechanism(s) responsible for these improvements remains unclear. Here, we assesse...

    Authors: Wesley J. Tucker, Binu P. Thomas, Nancy Puzziferri, T. Jake Samuel, Vlad G. Zaha, Ildiko Lingvay, Jaime Almandoz, Jing Wang, Edward A. Gonzales, R. Matthew Brothers and Michael D. Nelson

    Citation: Pilot and Feasibility Studies 2020 6:21

    Content type: Research

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  41. Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in social interaction and communication. Oxytocin (OXT), as a neuropeptide, plays a role in emotional and so...

    Authors: Xue-Jun Kong, Jun Liu, Jing Li, Kenneth Kwong, Madelyn Koh, Piyawat Sukijthamapan, Jason J. Guo, Zhenyu Jim Sun and Yiqing Song

    Citation: Pilot and Feasibility Studies 2020 6:20

    Content type: Study Protocol

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  42. Reducing alcohol consumption across populations would prevent many non-communicable diseases. Large packages increase food and non-alcoholic drink consumption and large glasses increase wine consumption. Small...

    Authors: Eleni Mantzari, Catherine Galloway, Gareth Hollands, Rachel Pechey, Zorana Zupan, Mark Pilling and Theresa Marteau

    Citation: Pilot and Feasibility Studies 2020 6:19

    Content type: Research

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  43. People of all ages are flooded with health claims about treatment effects (benefits and harms of treatments). Many of these are not reliable, and many people lack skills to assess their reliability. Primary sc...

    Authors: Allen Nsangi, Daniel Semakula, Sarah E. Rosenbaum, Andrew David Oxman, Matt Oxman, Angela Morelli, Astrid Austvoll-Dahlgren, Margaret Kaseje, Michael Mugisha, Anne-Marie Uwitonze, Claire Glenton, Simon Lewin, Atle Fretheim and Nelson Kaulukusi Sewankambo

    Citation: Pilot and Feasibility Studies 2020 6:18

    Content type: Research

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  44. Children born preterm may display cognitive, learning, and behaviour difficulties as they grow up. In particular, very premature birth (gestation age between 28 and less than 32 weeks) may put infants at incre...

    Authors: Oliver Perra, Sam Wass, Alison McNulty, David Sweet, Kostas Papageorgiou, Matthew Johnston, Aaron Patterson, Delfina Bilello and Fiona Alderdice

    Citation: Pilot and Feasibility Studies 2020 6:17

    Content type: Study Protocol

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  45. Despite recommendations for monitoring patients with chronic and high-risk conditions, gaps still remain. These gaps are exacerbated in outpatient care, where patients and clinicians face challenges related to...

    Authors: Matthew D. Hickey, Sarah Lisker, Shauna Brodie, Eric Vittinghoff, Marika D. Russell and Urmimala Sarkar

    Citation: Pilot and Feasibility Studies 2020 6:16

    Content type: Study Protocol

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  46. Diet quality in older people with chronic obstructive pulmonary disease (COPD) is associated with better health and lung function. Social factors, such as social support, social networks and participation in a...

    Authors: Ilse Bloom, Lindsay Welch, Ivaylo Vassilev, Anne Rogers, Karen Jameson, Cyrus Cooper, Sian Robinson and Janis Baird

    Citation: Pilot and Feasibility Studies 2020 6:15

    Content type: Research

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  47. This work concerns the activities in the last hour before bed for young children born to first-time parents, so called bedtime routines (BTR). These activities include amongst others tooth brushing, reading a ...

    Authors: George Kitsaras, Julia Allan and Iain A. Pretty

    Citation: Pilot and Feasibility Studies 2020 6:14

    Content type: Study Protocol

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  48. We hypothesise that a physical activity (PA) intervention will improve the quality of life (QoL) of people with a stoma. A feasibility study of the intervention and trial parameters is necessary to inform a fu...

    Authors: Gill Hubbard, Claire Taylor, Angus J. M. Watson, Julie Munro, William Goodman and Rebecca J. Beeken

    Citation: Pilot and Feasibility Studies 2020 6:12

    Content type: Research

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  49. Patients with metastatic breast cancer (MBC) are treated with a palliative approach with focus on controlling for disease symptoms and maintaining high quality of life. Information on individual needs of patie...

    Authors: Stephanie Stangl, Kirsten Haas, Felizitas A. Eichner, Anna Grau, Udo Selig, Timo Ludwig, Tanja Fehm, Tanja Stüber, Asarnusch Rashid, Alexander Kerscher, Ralf Bargou, Silke Hermann, Volker Arndt, Martin Meyer, Manfred Wildner, Hermann Faller…

    Citation: Pilot and Feasibility Studies 2020 6:11

    Content type: Research

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  50. Child stunting, an indicator of chronic malnutrition, is a global public health problem. Malnutrition during pregnancy and the first 2 years of life undermines the survival, growth, and development of children...

    Authors: Kimberly R. Jacob Arriola, Anna Ellis, Amy Webb-Girard, Emily Awino Ogutu, Emilie McClintic, Bethany Caruso and Matthew C. Freeman

    Citation: Pilot and Feasibility Studies 2020 6:10

    Content type: Research

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