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  1. Patellofemoral pain (PFP) is the most common knee condition among adolescents, with a prevalence of 6–7% resulting in reduced function and quality of life. Exercise therapy is recommended for treating PFP, but...

    Authors: Michael S. Rathleff, Camilla R. Rathleff, Sinead Holden, Kristian Thorborg and Jens L. Olesen
    Citation: Pilot and Feasibility Studies 2018 4:73
  2. Efficacy of acupuncture is difficult to demonstrate without a feasible double-blind milieu. Double-blind acupuncture needles have been validated in single session protocols with one or two needles but not been...

    Authors: Judith M. Schlaeger, Nobuari Takakura, Hiroyoshi Yajima, Miho Takayama, Alana D. Steffen, Elizabeth M. Gabzdyl, Robyn A. Nisi, Kathleen McGowan Gruber, Jason M. Bussell and Diana J. Wilkie
    Citation: Pilot and Feasibility Studies 2018 4:72
  3. Hypertension is the most common modifiable risk factor for cardiovascular disease, with an increasing prevalence with age, but with easily available medications to control it. Adverse effects of these medicati...

    Authors: Marcel Ruzicka, Brendan McCormick, Peter Magner, Tim Ramsay, Cedric Edwards, Ann Bugeja and Swapnil Hiremath
    Citation: Pilot and Feasibility Studies 2018 4:71
  4. Patellofemoral joint (PFJ) osteoarthritis (OA) is prevalent in middle-aged and older adults. Despite this, there are minimal studies which have examined conservative interventions for PFJ OA. Weakness of proxi...

    Authors: Lisa T. Hoglund, Laura Pontiggia and John D. Kelly IV
    Citation: Pilot and Feasibility Studies 2018 4:70
  5. Experimentation is a natural part of adolescent maturation. In conjunction with increased exposure to behaviours such as alcohol or substance use, and the potentially intensified influence of peer groups, unhe...

    Authors: Jan Pringle, Lawrence Doi, Divya Jindal-Snape, Ruth Jepson and John McAteer
    Citation: Pilot and Feasibility Studies 2018 4:69
  6. Parental supervised brushing (PSB) when initiated in infancy can lead to long-term protective home-based oral health habits thereby reducing the risk of dental caries. However, PSB is a complex behaviour with ...

    Authors: Ieva Eskyte, Kara Gray-Burrows, Jenny Owen, Bianca Sykes-Muskett, Tim Zoltie, Susanne Gill, Victoria Smith, Rosemary McEachan, Zoe Marshman, Robert West, Sue Pavitt and Peter Day
    Citation: Pilot and Feasibility Studies 2018 4:68
  7. INVESTIGATE-I (INVasive Evaluation before Surgical Treatment of Incontinence Gives Added Therapeutic Effect?) was a mixed methods study to assess the feasibility of a future randomised controlled trial of inva...

    Authors: Tara Homer, Jing Shen, Luke Vale, Elaine McColl, Douglas G. Tincello and Paul Hilton
    Citation: Pilot and Feasibility Studies 2018 4:67
  8. The most common physical deficit caused by a stroke is muscle weakness which limits a person’s mobility. Mobility encompasses activities necessary for daily functioning: getting in and out bed, on/off toilet, ...

    Authors: Angie Logan, Jennifer Freeman, Bridie Kent, Jillian Pooler, Siobhan Creanor, Jane Vickery, Doyo Enki, Andrew Barton and Jonathan Marsden
    Citation: Pilot and Feasibility Studies 2018 4:66
  9. Electronic patient-reported outcomes (e-PROs) may provide valid and feasible options for obtaining family input on their child’s functioning for care planning and outcome monitoring, but they have not been ado...

    Authors: Mary A. Khetani, Beth M. McManus, Kristen Arestad, Zachary Richardson, Renee Charlifue-Smith, Cordelia Rosenberg and Briana Rigau
    Citation: Pilot and Feasibility Studies 2018 4:65
  10. Sepsis is a common condition which kills between 36,000 and 64,000 people every year in the UK. Early recognition and management of sepsis has been shown to reduce mortality and improve the health and well-bei...

    Authors: Chris Moore, Jenna Bulger, Matt Morgan, Timothy Driscoll, Alison Porter, Saiful Islam, Mike Smyth, Gavin Perkins, Bernadette Sewell, Timothy Rainer, Prabath Nanayakkara, Chukwudi Okolie, Susan Allen, Greg Fegan, Jan Davies, Theresa Foster…
    Citation: Pilot and Feasibility Studies 2018 4:64
  11. Condoms remain the main protection against sexually transmitted infections (STIs) when used correctly and consistently. Yet, there are many reported barriers to their use such as negative attitudes, reduced se...

    Authors: Nicole Stone, Cynthia Graham, Sydney Anstee, Katherine Brown, Katie Newby and Roger Ingham
    Citation: Pilot and Feasibility Studies 2018 4:63
  12. Robotic wearable exoskeletons have been utilized as a gait training device in persons with spinal cord injury. This pilot study investigated the feasibility of offering exoskeleton-assisted gait training (EGT)...

    Authors: Shuo-Hsiu Chang, Taimoor Afzal, Jeffrey Berliner and Gerard E. Francisco
    Citation: Pilot and Feasibility Studies 2018 4:62
  13. Attention deficit hyperactivity disorder (ADHD) is a common and growing problem and a leading cause of child referrals to Child and Adult Mental Health Services (CAMHS). It is a drain on resources across natio...

    Authors: Philippa Fibert, Clare Relton, Tessa Peasgood and David Daley
    Citation: Pilot and Feasibility Studies 2018 4:61
  14. It is important to be able to reliably and feasibly measure infant and toddler physical activity in order to determine adherence to current physical activity guidelines and effects on early life development, g...

    Authors: Alessandra Prioreschi, Thomas Nappey, Kate Westgate, Patrick Olivier, Soren Brage and Lisa Kim Micklesfield
    Citation: Pilot and Feasibility Studies 2018 4:60
  15. Approximately 1 in 5 Canadians with HIV are unaware of their status. In many provinces and especially rural communities, barriers to HIV testing include lack of access, privacy concerns, and stigma. The availa...

    Authors: Jason Kielly, Deborah V. Kelly, Christine Hughes, Kristine Day, Stephanie Hancock, Shabnam Asghari, Jacqueline Gahagan, Carlo Marra and Hai Nguyen
    Citation: Pilot and Feasibility Studies 2018 4:59
  16. The interest of health care agencies, private payers and policy makers for patient-reported outcomes (PRO) is continuously increasing. There is a substantial need to improve capacity to collect and interpret r...

    Authors: MW. Skinner, C. Chai-Adisaksopha, R. Curtis, N. Frick, M. Nichol, D. Noone, B. O’Mahony, D. Page, J. S. Stonebraker and A. Iorio
    Citation: Pilot and Feasibility Studies 2018 4:58
  17. Depression is very common among stroke survivors with estimated prevalence rates of approximately 33% among stroke survivors, but treatment options are limited. Mindfulness-Based Stress Reduction (MBSR) is an ...

    Authors: Bhautesh Dinesh Jani, Robert Simpson, Maggie Lawrence, Sharon Simpson and Stewart W. Mercer
    Citation: Pilot and Feasibility Studies 2018 4:57
  18. Mood and anxiety disorders have a high lifetime prevalence, and their chronicity adds to the management burden of already scarce and strained mental health care resources, particularly in developing countries....

    Authors: A. S. J. Van der Watt, T. Roos, C. Beyer and S. Seedat
    Citation: Pilot and Feasibility Studies 2018 4:56
  19. Recent advances in treatment have given patients with chronic kidney disease (CKD) access to safer and more effective medications to treat comorbid hepatitis C virus (HCV) infection. Given the variety and comp...

    Authors: M. C. Politi, N. George, T. Li, K. M. Korenblat, K. J. Fowler, C. Ho, A. Liapakis, D. Roth and J. Yee
    Citation: Pilot and Feasibility Studies 2018 4:55
  20. Subthalamic nucleus deep brain stimulation (STN-DBS) reduces tremor, muscle stiffness, and bradykinesia in people with Parkinson’s Disease (PD). Walking speed, known to be reduced in PD, typically improves aft...

    Authors: Ryan P. Duncan, Linda R. Van Dillen, Jane M. Garbutt, Gammon M. Earhart and Joel S. Perlmutter
    Citation: Pilot and Feasibility Studies 2018 4:54
  21. While there is a growing interest in the therapeutic benefits of yoga, minority populations with arthritis tend to be under-represented in the research. Additionally, there is an absence of guidance in the lit...

    Authors: Kimberly R. Middleton, Michael M. Ward, Steffany Haaz Moonaz, Miriam Magaña López, Gladys Tataw-Ayuketah, Li Yang, Ana T. Acevedo, Zavera Brandon and Gwenyth R. Wallen
    Citation: Pilot and Feasibility Studies 2018 4:53
  22. Current guidelines for the provision of protein for critically ill patients are based on incomplete evidence, due to limited data from randomised controlled trials. The present pilot randomised controlled tria...

    Authors: Kate Fetterplace, Adam M. Deane, Audrey Tierney, Lisa Beach, Laura D. Knight, Thomas Rechnitzer, Adrienne Forsyth, Marina Mourtzakis, Jeffrey Presneill and Christopher MacIsaac
    Citation: Pilot and Feasibility Studies 2018 4:52
  23. Despite family meetings being widely used to facilitate discussion among patients, families, and clinicians in palliative care, there is limited evidence to support their use. This study aims to assess the acc...

    Authors: Philippa J. Cahill, Christine R. Sanderson, Elizabeth A. Lobb and Jane L. Phillips
    Citation: Pilot and Feasibility Studies 2018 4:51
  24. Cancer-related cognitive impairment (CRCI) may negatively affect upwards of 75% of cancer patients. Exercise and cognitive training, independently, may increase functional capacity and aspects of cognitive fun...

    Authors: Brent M. Peterson, Cynthia Johnson, Kaylene R. Case, Daniel Y. K. Shackelford, Jessica M. Brown, Trent L. Lalonde and Reid Hayward
    Citation: Pilot and Feasibility Studies 2018 4:50
  25. People with dementia progressively lose abilities and are prone to falling. Exercise- and activity-based interventions hold the prospect of increasing abilities, reducing falls, and slowing decline in cognitio...

    Authors: Rowan H. Harwood, Veronika van der Wardt, Sarah E. Goldberg, Fiona Kearney, Pip Logan, Vicky Hood-Moore, Vicky Booth, Jennie E. Hancox, Tahir Masud, Zoe Hoare, Andrew Brand, Rhiannon Tudor Edwards, Carys Jones, Roshan das Nair, Kristian Pollock, Maureen Godfrey…
    Citation: Pilot and Feasibility Studies 2018 4:49
  26. Rates of participation in Diabetes Prevention Programs (DPPs) are low. This may be due, in part, to low levels of autonomous motivation (i.e., motivation that arises from internal sources and sustains healthy ...

    Authors: Dina H. Griauzde, Jeffrey T. Kullgren, Brad Liestenfeltz, Caroline Richardson and Michele Heisler
    Citation: Pilot and Feasibility Studies 2018 4:48
  27. Weight management in pregnancy guidelines exist, although dissemination alone is an ineffective means of implementation. Midwives identify the need for support to overcome complex barriers to practice. An eval...

    Authors: Nicola Heslehurst, Judith Rankin, Catherine McParlin, Falko F. Sniehotta, Denise Howel, Stephen Rice and Elaine McColl
    Citation: Pilot and Feasibility Studies 2018 4:47
  28. Medically unexplained loss or alteration of voice—functional dysphonia—is the commonest presentation to speech and language therapists (SLTs). Besides the impact on personal and work life, functional dysphonia...

    Authors: Vincent Deary, Elaine McColl, Paul Carding, Tracy Miller and Janet Wilson
    Citation: Pilot and Feasibility Studies 2018 4:46
  29. Cognitive impairments, especially deficits of executive function, have been well documented as a core and early feature in Huntington’s disease (HD). Cognitive impairments represent considerable burden and can...

    Authors: Emma Yhnell, Hannah Furby, Rachel S. Breen, Lucy C. Brookes-Howell, Cheney J. G. Drew, Rebecca Playle, Gareth Watson, Claudia Metzler-Baddeley, Anne E. Rosser and Monica E. Busse
    Citation: Pilot and Feasibility Studies 2018 4:45
  30. Children born to mothers who experience social complexity (e.g. substance misuse, intimate partner violence, mental ill health, a history of maltreatment) are at increased risk for a range of adverse outcomes ...

    Authors: Geraldine Macdonald, Fiona Alderdice, Mike Clarke, Oliver Perra, Fiona Lynn, Theresa McShane and Sharon Millen
    Citation: Pilot and Feasibility Studies 2018 4:44
  31. Most cases of hypertension can be effectively treated with lifestyle changes together with medications, but within this population lies a group with more difficult to treat hypertension—those with apparent tre...

    Authors: Peter Hayes, Hannah Kielty, Monica Casey, Liam G. Glynn, Gerard J. Molloy, Hannah Durand, John Newell and Andrew W. Murphy
    Citation: Pilot and Feasibility Studies 2018 4:43
  32. Cerebral palsy (CP) is a developmental disorder of movement and posture that occurs due to damage to the developing nervous system. As part of therapy, wearable sensors that trigger interactive feedback may pr...

    Authors: Jaswandi Tushar Pitale and John H. Bolte IV
    Citation: Pilot and Feasibility Studies 2018 4:42
  33. Comprehensive geriatric assessment (CGA) represent an important component of geriatric acute hospital care for frail older people, secured by a multidisciplinary team who addresses the multiple needs of physic...

    Authors: Theresa Westgård, Isabelle Ottenvall Hammar, Eva Holmgren, Anna Ehrenberg, Aase Wisten, Anne W. Ekdahl, Synneve Dahlin-Ivanoff and Katarina Wilhelmson
    Citation: Pilot and Feasibility Studies 2018 4:41
  34. Chronic obstructive pulmonary disease (COPD) is a degenerative condition that can impair health-related quality of life (HRQoL). A number of self-management interventions, employing a variety of behavioural ch...

    Authors: Andrew R. Levy, Bashir Matata, Sam Pilsworth, Adrian Mcgonigle, Lyndsey Wigelsworth, Linda Jones, Nicola Pott, Max Bettany and Adrian W. Midgley
    Citation: Pilot and Feasibility Studies 2018 4:40
  35. Evidence has shown a relationship between dehydration, falls, and pulmonary aspiration among older adults in nursing homes, all of which contribute to loss of independence and quality of life. It is believed t...

    Authors: Márcia Duarte, Raquel Bouça-Machado, Josefa Domingos, Catarina Godinho and Joaquim J. Ferreira
    Citation: Pilot and Feasibility Studies 2018 4:39
  36. Major postoperative morbidity and mortality remain common despite efforts to improve patient outcomes. Health information technologies have the potential to actualize advances in perioperative patient care, bu...

    Authors: Teresa M. Murray-Torres, Frances Wallace, Mara Bollini, Michael S. Avidan and Mary C. Politi
    Citation: Pilot and Feasibility Studies 2018 4:38
  37. Given the generally incurable nature of metastatic non-small cell lung cancer (mNSCLC), patients and their romantic partners are at risk for existential/spiritual distress. Although a handful of dyadic psychos...

    Authors: Kathrin Milbury, Anne S. Tsao, Zhongxing Liao, April Owns, Rosalinda Engle, Edrea A. Gonzalez, Eduardo Bruera and Lorenzo Cohen
    Citation: Pilot and Feasibility Studies 2018 4:37
  38. Non-specialist healthcare providers, including primary and community healthcare workers, in low- and middle-income countries can effectively treat mental illness. However, scaling-up mental health services wit...

    Authors: Brandon A. Kohrt, Mark J. D. Jordans, Elizabeth L. Turner, Kathleen J. Sikkema, Nagendra P. Luitel, Sauharda Rai, Daisy R. Singla, Jagannath Lamichhane, Crick Lund and Vikram Patel
    Citation: Pilot and Feasibility Studies 2018 4:36
  39. Dietary interventions including consumption of flavonoids, plant compounds found in certain foods, may have the ability to improve fatigue. However, to date, no well-designed intervention studies assessing the...

    Authors: S. Coe, J. Collett, H. Izadi, D. T. Wade, M. Clegg, J. M. Harrison, E. Buckingham, A. Cavey, G. C. DeLuca, J. Palace and H. Dawes
    Citation: Pilot and Feasibility Studies 2018 4:35
  40. Essential strategies are needed to help reduce the number of post-operative complications and associated costs for breast cancer patients undergoing reconstructive breast surgery. Evidence suggests that local ...

    Authors: Suzie Cro, Saahil Mehta, Jian Farhadi, Billie Coomber and Victoria Cornelius
    Citation: Pilot and Feasibility Studies 2018 4:34
  41. Office workers have been identified as being at risk of accumulating high amounts of sedentary time in prolonged events during work hours, which has been associated with increased risk of a number of long-term...

    Authors: Catriona O’Dolan, Margaret Grant, Maggie Lawrence and Philippa Dall
    Citation: Pilot and Feasibility Studies 2018 4:33
  42. Early rehabilitation has been found to prevent delirium and weakness that can hamper the recovery of intensive care unit (ICU) survivors. Integrated clinical practice guidelines for managing patient pain, agit...

    Authors: Kellie Sosnowski, Marion L. Mitchell, Hayden White, Lynette Morrison, Joanne Sutton, Jessica Sharratt and Frances Lin
    Citation: Pilot and Feasibility Studies 2018 4:32
  43. Life after stroke can be an ongoing struggle with over half of all survivors reporting unmet emotional and social needs. In the United Kingdom’s (UK) national clinical guidelines for stroke, self-management is...

    Authors: Ella Clark, Nick S. Ward, Gianluca Baio and Fiona Jones
    Citation: Pilot and Feasibility Studies 2018 4:31
  44. Speech-related problems are common in Parkinson’s disease (PD), but there is little evidence for the effectiveness of standard speech and language therapy (SLT) or Lee Silverman Voice Treatment (LSVT LOUD®).

    Authors: Catherine M. Sackley, Christina H. Smith, Caroline E. Rick, Marian C. Brady, Natalie Ives, Smitaa Patel, Rebecca Woolley, Francis Dowling, Ramilla Patel, Helen Roberts, Sue Jowett, Keith Wheatley, Debbie Kelly, Gina Sands and Carl E. Clarke
    Citation: Pilot and Feasibility Studies 2018 4:30
  45. This study explored the feasibility of a randomised controlled withdrawal trial of antihypertensive medication in normotensive people with dementia. Feasibility aspects included response, recruitment, exclusio...

    Authors: Veronika van der Wardt, Jennifer K. Burton, Simon Conroy, Tomas Welsh, Pip Logan, Jaspal Taggar, Lukasz Tanajewski and John Gladman
    Citation: Pilot and Feasibility Studies 2018 4:29
  46. Transitioning into a new professional role is a stressful experience with consequences for mental and physical health, job satisfaction, organizational commitment, and turnover. New registered nurses seem to b...

    Authors: Elin Frögéli, Ann Rudman, Brjánn Ljótsson and Petter Gustavsson
    Citation: Pilot and Feasibility Studies 2018 4:28
  47. Currently, a PET-CT is used to assess the need for extended field radiotherapy of para-aortic lymph nodes (PALN) in International Federation of Gynaecology and Obstetrics (FIGO) stage IB2, IIA2–IVA (locally ad...

    Authors: Casper Tax, Karin Abbink, Maroeska M. Rovers, Ruud L. M. Bekkers and Petra L. M. Zusterzeel
    Citation: Pilot and Feasibility Studies 2018 4:27
  48. The atrial appendages are a tissue reservoir for cardiac stem cells. During on-pump coronary artery bypass graft (CABG) surgery, part of the right atrial appendage can be excised upon insertion of the right at...

    Authors: Annu Nummi, Tuomo Nieminen, Tommi Pätilä, Milla Lampinen, Miia L. Lehtinen, Sari Kivistö, Miia Holmström, Erika Wilkman, Kari Teittinen, Mika Laine, Juha Sinisalo, Markku Kupari, Esko Kankuri, Tatu Juvonen, Antti Vento, Raili Suojaranta…
    Citation: Pilot and Feasibility Studies 2017 3:74
  49. There is a lack of evidence-based substance use disorder treatment and services targeting returning inmates. Substance Use Programming for Person-Oriented Recovery and Treatment (SUPPORT) is a community-driven...

    Authors: Dennis P. Watson, Bradley Ray, Lisa Robison, Huiping Xu, Rhiannon Edwards, Michelle P. Salyers, James Hill and Sarah Shue
    Citation: Pilot and Feasibility Studies 2017 3:73
  50. Exercise referral schemes are recommended by the National Institute for Clinical Excellence (NICE) for physical activity promotion among inactive patients with health conditions or risk factors. Whilst there i...

    Authors: Jemma Hawkins, Michelle Edwards, Joanna Charles, Russell Jago, Mark Kelson, Kelly Morgan, Simon Murphy, Emily Oliver, Sharon Simpson, Rhiannon Tudor Edwards and Graham Moore
    Citation: Pilot and Feasibility Studies 2017 3:51

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