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  1. Content type: Study Protocol

    Men with metastatic castrate-resistant prostate cancer can experience an array of treatment-related side effects. Accumulating evidence suggests exercise may alleviate some of these adversities and assist in d...

    Authors: Malcolm Brown, Marie Murphy, Lauri McDermott, Helen McAneney, Joe M. O’Sullivan, Suneil Jain and Gillian Prue

    Citation: Pilot and Feasibility Studies 2019 5:102

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  2. Content type: Study Protocol

    The evidence-based practice of active surveillance to monitor men with favorable-risk prostate cancer in lieu of initial definitive treatment is becoming more common. However, there are barriers to effective i...

    Authors: Benjamin Cedars, Sarah Lisker, Hala T. Borno, Puneet Kamal, Benjamin Breyer and Urmimala Sarkar

    Citation: Pilot and Feasibility Studies 2019 5:101

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  3. Content type: Study Protocol

    Dental attendance provides an important opportunity for dental teams to explore with parents the oral health behaviours they undertake for their young children (0–5 years old). For these discussions to be effe...

    Authors: Kerina Tull, Kara A. Gray-Burrows, Amrit Bhatti, Jenny Owen, Lucy Rutter, Timothy Zoltie, Jayne Purdy, Erin Giles, Carron Paige, Morvin Patel, Zoe Marshman, Robert West, Sue Pavitt and Peter F. Day

    Citation: Pilot and Feasibility Studies 2019 5:100

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  4. Content type: Research

    Disparities in diagnosis and control of type 2 diabetes mellitus are most evident in African Americans (AAs) with lower socioeconomic status. Health literacy is an important predictor of adequate self-manageme...

    Authors: Hae-Ra Han, Manka Nkimbeng, Olayinka Ajomagberin, Kelli Grunstra, Phyllis Sharps, Susan Renda and Nisa Maruthur

    Citation: Pilot and Feasibility Studies 2019 5:99

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  5. Content type: Study Protocol

    Acute lower respiratory tract infection is a common acute infection managed in primary care. The current dominant management strategy in the UK is antibiotics, despite widespread publicity regarding antimicrob...

    Authors: Amy Whitehead, Catherine Simpson, Merlin Willcox, Frances Webley, Alastair D. Hay, Chris Butler, Lily Yao, Emma Wrixon, Margaret Bell, Jennifer Bostock, Paul Little, Gareth Griffiths and Michael Moore

    Citation: Pilot and Feasibility Studies 2019 5:98

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  6. Content type: Research

    Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide, but few studies have evaluated the feasibility of routine patient-reported outcome measures (PROMs) in this illness. ...

    Authors: Melanie A. Lloyd, Clarice Y. Tang, Emily J. Callander, Edward D. Janus, Amalia Karahalios, Elizabeth H. Skinner, Stephanie Lowe and Harin A. Karunajeewa

    Citation: Pilot and Feasibility Studies 2019 5:97

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  7. Content type: Research

    The Regaining Confidence after Stroke (RCAS) course was designed to facilitate adjustment for people with stroke discharged from rehabilitation. The aim of the trial was to evaluate the feasibility of conducti...

    Authors: Jane C. Horne, Kate E. Hooban, Nadina B. Lincoln and Pip A. Logan

    Citation: Pilot and Feasibility Studies 2019 5:96

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  8. Content type: Study Protocol

    Although the diagnosis and treatment of a primary brain tumor present unique challenges to patients and their family caregivers, evidence-based supportive care interventions are generally lacking. The primary ...

    Authors: Kathrin Milbury, Jing Li, Shiao-Pei Weathers, Tina Shih, Smitha Malliaha, Yisheng Li and Lorenzo Cohen

    Citation: Pilot and Feasibility Studies 2019 5:95

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  9. Content type: Research

    Oxygen consumption after surgery is increased in response to the tissue trauma sustained intra-operatively and the subsequent systemic inflammatory response that ensues. The cardio-respiratory system must matc...

    Authors: H. E. Taylor, K. Simons, C. Willmott, R. E. R. Smith and D. E. P. Bramley

    Citation: Pilot and Feasibility Studies 2019 5:94

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  10. Content type: Research

    Relatives of long-term missing persons need to deal with uncertainties related to the disappearance. These uncertainties may give rise to ruminative thinking about the causes and consequences of the loss. Focu...

    Authors: Lonneke I. M. Lenferink, Jos de Keijser, Ineke Wessel and Paul A. Boelen

    Citation: Pilot and Feasibility Studies 2019 5:93

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  11. Content type: Study Protocol

    Patient-reported outcomes (PRO) are used to measure the effectiveness of interventions for management of chronic conditions such as chronic obstructive pulmonary disease. Many of these instruments require resp...

    Authors: Sheree M. S. Smith, Stephen Jan, Joseph Descallar and Guy B. Marks

    Citation: Pilot and Feasibility Studies 2019 5:92

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  12. Content type: Research

    Despite the large number of evidence-based practices (EBPs) ready for implementation, they are the exception in usual care, especially for ethnic minority patients, who may not have access to trained health pr...

    Authors: Ana A. Baumann, Melanie M. Domenech Rodríguez, Elizabeth Wieling, J. Rubén Parra-Cardona, Laura A. Rains and Marion S. Forgatch

    Citation: Pilot and Feasibility Studies 2019 5:91

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  13. Content type: Research

    Foot orthoses have the potential to be an efficacious treatment for patellofemoral osteoarthritis (PFOA) but have not been evaluated in clinical trials in this population. This study aimed to determine the: (i...

    Authors: Jade M. Tan, Hylton B. Menz, Kay M. Crossley, Shannon E. Munteanu, Harvi F. Hart, Kane J. Middleton, Anne J. Smith and Natalie J. Collins

    Citation: Pilot and Feasibility Studies 2019 5:90

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  14. Content type: Research

    Residents in care homes are often very frail, have complex medicine regimens and are at high risk of adverse drug events. It has been recommended that one healthcare professional should assume responsibility f...

    Authors: Jacqueline Inch, Frances Notman, Christine M. Bond, David P. Alldred, Antony Arthur, Annie Blyth, Amrit Daffu-O’Reilly, Joanna Ford, Carmel M. Hughes, Vivienne Maskrey, Anna Millar, Phyo K. Myint, Fiona M. Poland, Lee Shepstone, Arnold Zermansky, Richard Holland…

    Citation: Pilot and Feasibility Studies 2019 5:89

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  15. Content type: Study Protocol

    There is overwhelming evidence to support the promotion of physical activity in adults in terms of benefits to well-being, physical and mental health. Physical activity guidelines suggest that adults should ac...

    Authors: Andrew O’Regan, Liam Glynn, Enrique Garcia Bengoechea, Monica Casey, Amanda Clifford, Alan Donnelly, Andrew W. Murphy, Stephen Gallagher, Paddy Gillespie, John Newell, Mary Harkin, Phelim Macken, John Sweeney, Mo Foley-Walsh, Geraldine Quinn, Kwok Ng…

    Citation: Pilot and Feasibility Studies 2019 5:88

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  16. Content type: Study Protocol

    People with temporal lobe epilepsy (TLE) report significant problems with learning and memory. There are no effective therapies for combatting these problems in people with TLE, resulting in an unmet therapeut...

    Authors: Cheney J. G. Drew, Mark Postans, Cateno Petralia, Rachel McNamara, Philip Pallmann, Dave Gillespie, Lisa H. Evans, Nils Muhlert, Mia Winter, Khalid Hamandi and William P. Gray

    Citation: Pilot and Feasibility Studies 2019 5:87

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  17. Content type: Study Protocol

    Frailty is a common and clinically significant condition in older adults, predominantly due to its association with adverse health outcomes such as hospitalisation, disability and mortality. Exercise intervent...

    Authors: Paul Doody, Janet M. Lord and Anna C. Whittaker

    Citation: Pilot and Feasibility Studies 2019 5:86

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  18. Content type: Research

    The purpose of this study was to pilot test two sickle cell-specific instruments, the Adult Sickle Cell Quality of Life Measurement Information System (ASCQ-Me) and Jenerette Self-Care Assessment Tool (J-SAT),...

    Authors: Dominique Bulgin, Christian Douglas and Paula Tanabe

    Citation: Pilot and Feasibility Studies 2019 5:85

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  19. Content type: Research

    Many interventions designed to meet physical activity guideline recommendations focus on a single component (e.g., walking), to the detriment of other elements of a healthy lifestyle, such as reducing prolonge...

    Authors: Maureen C. Ashe, Nicola Y. Edwards, Amanda Taylor, Laura Burnett, Lora Giangregorio, Kate Milne, Lindy Clemson and Lena Fleig

    Citation: Pilot and Feasibility Studies 2019 5:84

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  20. Content type: Study Protocol

    Religious mass gatherings (MGs) have always been an integral part of our society. At the outset, mass-gathering events provide challenging settings to plan a suitable emergency public health response. Publishe...

    Authors: Upasana Sharma, B. R. Desikachari and Sankara Sarma

    Citation: Pilot and Feasibility Studies 2019 5:83

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  21. Content type: Study Protocol

    There is international recognition of the need for creative, classroom-based interventions to support children at risk of low academic achievement and well-being, due to poor attention and language skills on s...

    Authors: Anita Rowe, Jill Titterington and Laurence Taggart

    Citation: Pilot and Feasibility Studies 2019 5:82

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  22. Content type: Study Protocol

    Optimal mental health is critical for a child’s learning and academic functioning. As a universal service, early education centres play an important role in promoting children’s mental health. Social-emotional...

    Authors: Maya Yaari, Jane Sheehan, Frank Oberklaid and Harriet Hiscock

    Citation: Pilot and Feasibility Studies 2019 5:81

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  23. Content type: Research

    Pancreatic cancer has one of the highest mortality rates of any malignancy, placing a substantial burden on patients and families with high unmet informational and supportive care needs. Nevertheless, access t...

    Authors: Eryn Tong, Chris Lo, Shari Moura, Kelly Antes, Sarah Buchanan, Venissa Kamtapersaud, Gerald M. Devins, Camilla Zimmermann, Steven Gallinger and Gary Rodin

    Citation: Pilot and Feasibility Studies 2019 5:80

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  24. Content type: Research

    Clozapine-induced hypersalivation (CIH) is a common side effect of clozapine treatment and is disliked by clozapine patients, potentially threatening adherence to clozapine treatment. We proposed a trial of al...

    Authors: Inti Qurashi, Simon Chu, Richard Drake, Victoria Hartley, Imran Chaudhry, J. F. W. Deakin and Nusrat Husain

    Citation: Pilot and Feasibility Studies 2019 5:79

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  25. Content type: Study Protocol

    Physical activity (PA) is positively associated with quality of life. People with a stoma are less likely to engage in PA than those without a stoma.

    Authors: Gill Hubbard, Rebecca J. Beeken, Claire Taylor, Angus J. M. Watson, Julie Munro and William Goodman

    Citation: Pilot and Feasibility Studies 2019 5:78

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  26. Content type: Research

    In managing hip fracture, effective pain relief before admission to hospital is difficult without risking side effects. Although emergency departments routinely use fascia iliaca compartment block (FICB), ther...

    Authors: Jenna K. Jones, Bridie A. Evans, Greg Fegan, Simon Ford, Katy Guy, Sian Jones, Leigh Keen, Ashrafunnesa Khanom, Mirella Longo, Ian Pallister, Nigel Rees, Ian T. Russell, Anne C. Seagrove, Alan Watkins and Helen A. Snooks

    Citation: Pilot and Feasibility Studies 2019 5:77

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  27. Content type: Study Protocol

    The human microbiota has a broad range of functions contributing to metabolic processes and the activities of our immune system. Its influence on health, well-being and chronic diseases are discussed in variou...

    Authors: Laura Schmitz, Nina Ferrari, Andreas Schwiertz, Kerstin Rusch, Ulrich Woestmann, Esther Mahabir and Christine Graf

    Citation: Pilot and Feasibility Studies 2019 5:76

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  28. Content type: Study Protocol

    A number of children experience difficulties with social communication and this has long-term deleterious effects on their mental health, social development and education. The proposal presented in this articl...

    Authors: Suzanne Murphy, Victoria Joffe, David Messer, Sarah Crafter, Jessica Radley, Sailaa Sunthararajah, Kerry Bell, Belen Corbacho, Caroline Fairhurst, Sara Rodgers, David Torgerson and Charlie Welch

    Citation: Pilot and Feasibility Studies 2019 5:75

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  29. Content type: Research

    Tobacco smoking is a major risk factor for several oral diseases, including periodontitis, and electronic cigarettes (e-cigarettes) are increasingly being used for smoking cessation. This study aimed to assess...

    Authors: Richard Holliday, Philip M. Preshaw, Vicky Ryan, Falko F. Sniehotta, Suzanne McDonald, Linda Bauld and Elaine McColl

    Citation: Pilot and Feasibility Studies 2019 5:74

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  30. Content type: Study Protocol

    Fun For Wellness (FFW) is an online behavioral intervention designed to promote growth in well-being and physical activity by providing capability-enhancing learning opportunities to participants. The conceptu...

    Authors: Nicholas D. Myers, Seungmin Lee, André G. Bateman, Isaac Prilleltensky, Kimberly A. Clevenger, Karin A. Pfeiffer, Samantha Dietz, Ora Prilleltensky, Adam McMahon and Ahnalee M. Brincks

    Citation: Pilot and Feasibility Studies 2019 5:73

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  31. Content type: Study Protocol

    Critically ill patients frequently develop acute kidney injury that necessitates renal replacement therapy (RRT). At some centers, critically ill patients who are hemodynamically unstable and require RRT are t...

    Authors: Edward G. Clark, Lauralyn McIntyre, Tim Ramsay, Alan Tinmouth, Greg Knoll, Pierre-Antoine Brown, Irene Watpool, Rebecca Porteous, Kaitlyn Montroy, Sophie Harris, Jennifer Kong and Swapnil Hiremath

    Citation: Pilot and Feasibility Studies 2019 5:72

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  32. Content type: Study Protocol

    Objectives:

    (a)
    Refine a bespoke enhanced support intervention (ESI) (including self-help materials, intervention manual a...
     

    Authors: Elizabeth Littlewood, Shehzad Ali, Jay Badenhorst, Della Bailey, Clare Bambra, Carolyn Chew-Graham, Elizabeth Coleman, Suzanne Crosland, Samantha Gascoyne, Simon Gilbody, Catherine Hewitt, Claire Jones, Ada Keding, Charlotte Kitchen, Dean McMillan, Caroline Pearson…

    Citation: Pilot and Feasibility Studies 2019 5:71

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  33. Content type: Study Protocol

    Femoral neck fractures in patients ≤ 60 years of age are often very different injuries compared to low-energy, hip fractures in elderly patients and are difficult to manage because of inherent problems associa...

    Authors: Gerard P. Slobogean, Sheila Sprague, Sofia Bzovsky, Diane Heels-Ansdell, Lehana Thabane, Taryn Scott and Mohit Bhandari

    Citation: Pilot and Feasibility Studies 2019 5:70

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  34. Content type: Research

    To evaluate the feasibility of integrating vestibular rehabilitation and cognitive behaviour therapy (VR-CBT) for people with persistent dizziness in primary care.

    Authors: Lene Kristiansen, L. H. Magnussen, B. Juul-Kristensen, S. Mæland, S. H. G. Nordahl, A. Hovland, T. Sjøbø and K. T. Wilhelmsen

    Citation: Pilot and Feasibility Studies 2019 5:69

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  35. Content type: Study Protocol

    Deimplementation, the systematic elimination of low-value practices, has emerged as an important focus within implementation science. Bronchiolitis is the leading cause of infant hospitalization. Among stable ...

    Authors: Irit R. Rasooly, Rinad S. Beidas, Courtney Benjamin Wolk, Frances Barg, Christopher P. Landrigan, Amanda Schondelmeyer, Patrick W. Brady, Lisa M. McLeod and Christopher P. Bonafide

    Citation: Pilot and Feasibility Studies 2019 5:68

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  36. Content type: Study Protocol

    Opioid use disorder (OUD) and deaths related to the chronic use of opioids have increased significantly over the last two decades. Chronic consumption of opioids has been documented in many patients with traum...

    Authors: M. Bérubé, V. Deslauriers, S. Leduc, V. Turcotte, S. Dupuis, I. Roy, S. Clairoux, S. Panic and M. Nolet

    Citation: Pilot and Feasibility Studies 2019 5:67

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  37. Content type: Study protocol

    The high burden of bereavement in sub-Saharan Africa is largely attributable to HIV, cancer, and other non-communicable diseases. However, interventions to improve grief and bereavement are rare. Given high ra...

    Authors: Barbara Mutedzi, Lisa Langhaug, Jennifer Hunt, Kennedy Nkhoma and Richard Harding

    Citation: Pilot and Feasibility Studies 2019 5:66

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  38. Content type: Research

    Clinical guidelines for management of low back pain (LBP) are not routinely implemented in practice, and guidelines rarely offer tools for implementation. Therefore, we developed GLA:D® Back, a standardised in...

    Authors: Alice Kongsted, Jan Hartvigsen, Eleanor Boyle, Inge Ris, Per Kjaer, Line Thomassen and Werner Vach

    Citation: Pilot and Feasibility Studies 2019 5:65

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  39. Content type: Study Protocol

    While people who are homeless often experience poor mental and physical health and problem substance use, getting access to appropriate services can be challenging. The development of trusting relationships wi...

    Authors: Tessa Parkes, Catriona Matheson, Hannah Carver, John Budd, Dave Liddell, Jason Wallace, Bernie Pauly, Maria Fotopoulou, Adam Burley, Isobel Anderson, Graeme MacLennan and Rebecca Foster

    Citation: Pilot and Feasibility Studies 2019 5:64

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  40. Content type: Study Protocol

    While existing psychological treatments for depression are effective for many, a significant proportion of depressed individuals do not respond to current approaches and few remain well over the long-term. Anh...

    Authors: Barnaby D. Dunn, Emily Widnall, Nigel Reed, Rod Taylor, Christabel Owens, Anne Spencer, Gerda Kraag, Gerjo Kok, Nicole Geschwind, Kim Wright, Nicholas J. Moberly, Michelle L. Moulds, Andrew K. MacLeod, Rachel Handley, David Richards, John Campbell…

    Citation: Pilot and Feasibility Studies 2019 5:63

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  41. Content type: Study Protocol

    Families applying for asylum have often experienced multiple potentially traumatic events and continue to face stressors during their resettlement. Studies have indicated that traumatic events can negatively i...

    Authors: Carlijn M. van Es, Trudy Mooren, Marieke Zwaanswijk, Hans te Brake and Paul A. Boelen

    Citation: Pilot and Feasibility Studies 2019 5:62

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  42. Content type: Study Protocol

    Alcohol-related harm is currently estimated to cost the National Health Service (NHS) in England £3.5 bn a year. Of the estimated 1.6 million people with some degree of alcohol dependence, some 600,000 are bel...

    Authors: Christos Kouimtsidis, Ben Houghton, Heather Gage, Caitlin Notley, Vivienne Maskrey, Allan Clark, Richard Holland, Anne Lingford-Hughes, Bhaskar Punukollu and Theodora Duka

    Citation: Pilot and Feasibility Studies 2019 5:59

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  43. Content type: Study Protocol

    Family carepartner management and support can improve stroke survivor recovery, yet research has placed little emphasis on how to integrate families into the rehabilitation process without increasing negative ...

    Authors: Sarah Blanton, Patricia C. Clark, Robert H. Lyles, George Cotsonis, Brian D. Jones, Aimee Reiss, Steven L. Wolf and Sandra Dunbar

    Citation: Pilot and Feasibility Studies 2019 5:58

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  44. Content type: Study Protocol

    Optimal management of chronic arthritic pain experienced by older adults involves applying active self-management strategies every day. Cost-effective and innovative strategies to help build older people’s pai...

    Authors: Priyanka Bhattarai, Toby R. O. Newton-John and Jane L. Phillips

    Citation: Pilot and Feasibility Studies 2019 5:57

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  45. Content type: Research

    Viscosupplementation with new-generation, polyol-containing, cross-linked hyaluronic acid (HA) gels reduces joint inflammation in patients with knee osteoarthritis. Gait analysis is a complementary outcome mea...

    Authors: Luis Carlos Pereira, Claude Schweizer, Sara Moufarrij, Swenn M. Krähenbühl, Julien Favre, Gerald Gremion, Lee Ann Applegate and Brigitte M. Jolles

    Citation: Pilot and Feasibility Studies 2019 5:56

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  46. Content type: Research

    Approximately 9% of a trauma surgeon’s workload in the UK is managing ankle fractures. Following an ankle fracture immobilisation with a plaster cast or removable orthotic is usual. The aim of this research wa...

    Authors: Rebecca S. Kearney, Rebecca McKeown, Daniel Gallacher, Jaclyn Brown, Dipesh Mistry, Nick Parsons, Jonathan Young and Matthew Costa

    Citation: Pilot and Feasibility Studies 2019 5:55

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  47. Content type: Study Protocol

    Osteoarthritis is a highly prevalent condition in older adults, that causes many sufferers to require a hip or knee replacement in order to improve their quality of life and reduce pain. Individuals waiting fo...

    Authors: Justin Avery Aunger, Colin James Greaves, Edward T. Davis and Carolyn Anne Greig

    Citation: Pilot and Feasibility Studies 2019 5:54

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  48. Content type: Research

    The conduct of high-quality pilot studies can help inform the success of larger clinical trials. Guidelines have been recently developed for the reporting of pilot trials.

    Authors: Sarah Daisy Kosa, Jillian Monize, Alvin Leenus, Selvin Leenus, Simranjit Samra, Sylwia Szwiega, Daniel Shi, Sara Valvasori, Amiram Gafni, Charmaine E. Lok and Lehana Thabane

    Citation: Pilot and Feasibility Studies 2019 5:53

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