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  1. Research

    Aquatic therapy for boys with Duchenne muscular dystrophy (DMD): an external pilot randomised controlled trial

    Standard treatment of Duchenne muscular dystrophy (DMD) includes regular physiotherapy. There are no data to show whether adding aquatic therapy (AT) to land-based exercises helps maintain motor function. We a...

    Daniel Hind, James Parkin, Victoria Whitworth, Saleema Rex, Tracey Young, Lisa Hampson, Jennie Sheehan, Chin Maguire, Hannah Cantrill, Elaine Scott, Heather Epps, Marion Main, Michelle Geary, Heather McMurchie, Lindsey Pallant, Daniel Woods…

    Pilot and Feasibility Studies 2017 3:16

    Published on: 27 March 2017

  2. Research

    Improving medication management for patients with multimorbidity in primary care: a qualitative feasibility study of the MY COMRADE implementation intervention

    For the majority of patients with multimorbidity, the prescription of multiple long-term medications (polypharmacy) is indicated. However, polypharmacy poses a risk of adverse drug events, drug interactions an...

    Carol Sinnott, Molly Byrne and Colin P. Bradley

    Pilot and Feasibility Studies 2017 3:14

    Published on: 20 March 2017

  3. Study Protocol

    Promoting adherence to treatment for latent TB infection through mobile phone text messaging: study protocol for a pilot randomized controlled trial

    An estimated two billion people, over one third of the world’s population, have latent infection with Mycobacterium tuberculosis (LTBI). Patient adherence to LTBI treatment is currently poor given that individual...

    Eyal Oren, Melanie L. Bell, Francisco Garcia, Carlos Perez-Velez and Lynn B. Gerald

    Pilot and Feasibility Studies 2017 3:15

    Published on: 13 March 2017

  4. Study Protocol

    A protocol for a cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination among girls

    Uptake of the human papillomavirus (HPV) vaccine in the UK is good, but there are pockets of the community who remain unprotected. Immunisation teams usually require written parental consent for a girl to rece...

    Alice S. Forster, Victoria Cornelius, Lauren Rockliffe, Laura A. V. Marlow, Helen Bedford and Jo Waller

    Pilot and Feasibility Studies 2017 3:13

    Published on: 6 March 2017

  5. Study Protocol

    A protocol for a feasibility randomised controlled trial to assess the difference between functional bracing and plaster cast for the treatment of ankle fractures

    UK Hospital Episode Statistics 2013–2014 recorded 57,286 fractures of the lower limb including the ankle. This figure is expected to continue to increase due to a greater population of older adults. Following ...

    Rebecca S. Kearney, Nick Parsons, Dipesh Mistry, Jonathan Young, Jaclyn Brown, Joanne O’Beirne-Elliman and Matthew Costa

    Pilot and Feasibility Studies 2017 3:11

    Published on: 1 March 2017

  6. Study Protocol

    The Herts and minds study: evaluating the effectiveness of mentalization-based treatment (MBT) as an intervention for children in foster care with emotional and/or behavioural problems: a phase II, feasibility, randomised controlled trial

    A significant proportion of children in the social care system in England present with mental health problems, with the majority experiencing some form of emotional and behavioural difficulties. The most effec...

    Nick Midgley, Sarah Jane Besser, Helen Dye, Pasco Fearon, Tim Gale, Kiri Jefferies-Sewell, Karen Irvine, Joyce Robinson, Solange Wyatt, David Wellsted and Sally Wood

    Pilot and Feasibility Studies 2017 3:12

    Published on: 22 February 2017

  7. Study Protocol

    Using brothel leadership to promote condom use among brothel-based female sex workers in Abuja, Nigeria: study protocol for a cluster randomized pilot trial

    The HIV prevalence among female populations involved in sex work in Nigeria has heightened interest in HIV prevention programming for this sub-population with brothel-based female sex workers (BB FSWs) having ...

    Uchenna Okafor, Rik Crutzen, Ifeanyi Okekearu, Sylvia Adebajo, Adaora Uzoh, Egbe Aneotah Awo, Chukwuemeka Chima, Ogechukwu Agwagwa and Bart van den Borne

    Pilot and Feasibility Studies 2017 3:10

    Published on: 20 February 2017

  8. Study Protocol

    Protocol for the evaluation of a digital storytelling approach to address stigma and improve readiness to seek services among veterans

    Research suggests that at least 10% of veterans returning from Iraq and Afghanistan meet criteria for posttraumatic stress disorder (PTSD) related to their military experiences. National dissemination initiati...

    Brian E. Bunnell, Tatiana M. Davidson, Jessica L. Hamblen, Danna L. Cook, Anouk L. Grubaugh, Brian E. Lozano, Peter W. Tuerk and Kenneth J. Ruggiero

    Pilot and Feasibility Studies 2017 3:7

    Published on: 17 February 2017

  9. Research

    Development and refinement of a complex intervention within cardiac rehabilitation services: experiences from the CADENCE feasibility study

    Patients who experience a cardiac event are at higher risk of developing depression than the general population. Despite this, cardiac rehabilitation (CR) programmes do not provide a systematic approach to psy...

    Rachel Winder, Suzanne H. Richards, John L. Campbell, David A. Richards, Chris Dickens, Manish Gandhi, Christine Wright and Katrina Turner

    Pilot and Feasibility Studies 2017 3:9

    Published on: 13 February 2017

  10. Research

    Developing and testing an electronic medication administration monitoring device for community dwelling seniors: a feasibility study

    Medication non-adherence, polypharmacy, and adverse drug events are major healthcare issues leading to significant morbidity, mortality, and healthcare expenditures. Currently, there are no methods to systemat...

    Henry Yu-Hin Siu, Dee Mangin, Michelle Howard, David Price and David Chan

    Pilot and Feasibility Studies 2017 3:5

    Published on: 1 February 2017

  11. Study Protocol

    Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial

    Adequate pain relief at the point of injury and during transport to hospital is a major challenge in all acute traumas, especially for those with hip fractures, whose injuries are difficult to immobilise and w...

    Jenna K. Bulger, Alan Brown, Bridie A. Evans, Greg Fegan, Simon Ford, Katy Guy, Sian Jones, Leigh Keen, Ashrafunnesa Khanom, Ian Pallister, Nigel Rees, Ian T. Russell, Anne C. Seagrove and Helen A. Snooks

    Pilot and Feasibility Studies 2017 3:8

    Published on: 23 January 2017

  12. Study Protocol

    Comparing counselling alone versus counselling supplemented with guided use of a well-being app for university students experiencing anxiety or depression (CASELOAD): protocol for a feasibility trial

    University counselling services face a unique challenge to offer short-term therapeutic support to students presenting with complex mental health needs and in a setting which suits the academic timetable. The ...

    Emma Broglia, Abigail Millings and Michael Barkham

    Pilot and Feasibility Studies 2017 3:3

    Published on: 23 January 2017

  13. Study Protocol

    Distant delivery of a mindfulness-based intervention for people with Parkinson’s disease: the study protocol of a randomised pilot trial

    Psychological difficulties, especially depression and anxiety, are the most prevalent non-motor symptoms in Parkinson’s disease. Pharmacological treatments for these conditions appear relatively ineffective in...

    A. Bogosian, C. S. Hurt, D. Vasconcelos e Sa, J. V. Hindle, L. McCracken and P. Cubi-Molla

    Pilot and Feasibility Studies 2017 3:4

    Published on: 16 January 2017

  14. Research

    Smoking treatment optimisation in pharmacies (STOP): a cluster randomised pilot trial of a training intervention

    UK government policy aims to strengthen the role of community pharmacies in health promotion. Thus, we conducted feasibility studies for an intervention to enhance delivery of the NHS Smoking Cessation Service.

    V. W. Madurasinghe, Ratna Sohanpal, Wai James, Liz Steed, Sandra Eldridge, SJC Taylor, C. Griffiths and Robert Walton

    Pilot and Feasibility Studies 2017 3:1

    Published on: 10 January 2017

  15. Study Protocol

    Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study)

    Women with highly penetrant BRCA mutations have a 55–60% lifetime risk for breast cancer and a 16–59% lifetime risk for ovarian cancer. However, penetrance differs interindividually, indicating that environmen...

    Marion Kiechle, Christoph Engel, Anika Berling, Katrin Hebestreit, Stephan Bischoff, Ricarda Dukatz, Wolf-Dieter Gerber, Michael Siniatchkin, Katharina Pfeifer, Sabine Grill, Maryam Yahiaoui-Doktor, Ellen Kirsch, Uwe Niederberger, Nicole Marter, Ute Enders, Markus Löffler…

    Pilot and Feasibility Studies 2016 2:74

    Published on: 19 December 2016

  16. Research

    Evaluating acupuncture and standard care for pregnant women with back pain: the EASE Back pilot randomised controlled trial (ISRCTN49955124)

    Low back pain (LBP) and pelvic girdle pain (PGP) during pregnancy are common and often accepted as a ‘normal’ part of pregnancy. Many women receive little in the way of treatment, and yet pain interferes with ...

    Annette Bishop, Reuben Ogollah, Bernadette Bartlam, Panos Barlas, Melanie A. Holden, Khaled M. Ismail, Sue Jowett, Martyn Lewis, Alison Lloyd, Christine Kettle, Jesse Kigozi and Nadine E. Foster

    Pilot and Feasibility Studies 2016 2:72

    Published on: 12 December 2016

  17. Study Protocol

    Investigating the differential impact of school and community-based integrated control programmes for soil-transmitted helminths in Timor-Leste: the (S)WASH-D for Worms pilot study protocol

    Water, sanitation and hygiene (WASH) interventions represent an important component of soil-transmitted helminth (STH) infection control, alongside the administration of anthelmintic drugs, which are generally...

    Naomi E. Clarke, Archie C. A. Clements, Stuart Bryan, John McGown, Darren Gray and Susana V. Nery

    Pilot and Feasibility Studies 2016 2:69

    Published on: 8 December 2016

  18. Update

    Update to a protocol for a feasibility cluster randomised controlled trial of a peer-led school-based intervention to increase the physical activity of adolescent girls (PLAN-A)

    Physical activity levels are low amongst adolescent girls, and this population faces specific barriers to being active. Peer influences on health behaviours are important in adolescence, and peer-led intervent...

    Simon J. Sebire, Mark J. Edwards, Rona Campbell, Russell Jago, Ruth Kipping, Kathryn Banfield, Bryar Kadir, Kirsty Garfield, Ronan A. Lyons, Peter S. Blair and William Hollingworth

    Pilot and Feasibility Studies 2016 2:68

    Published on: 1 December 2016

  19. Study Protocol

    Evaluation of the effectiveness of music therapy in improving the quality of life of palliative care patients: a randomised controlled pilot and feasibility study

    Music therapy is frequently used as a palliative therapy. In consonance with the goals of palliative care, the primary aim of music therapy is to improve people’s quality of life by addressing their psychologi...

    Tracey McConnell, Lisa Graham-Wisener, Joan Regan, Miriam McKeown, Jenny Kirkwood, Naomi Hughes, Mike Clarke, Janet Leitch, Kerry McGrillen and Sam Porter

    Pilot and Feasibility Studies 2016 2:70

    Published on: 29 November 2016

  20. Study Protocol

    Trial of Optimal Personalised Care After Treatment for Gynaecological cancer (TOPCAT-G): a study protocol for a randomised feasibility trial

    Gynaecological cancers are diagnosed in over 1000 women in Wales every year. We estimate that this is costing the National Health Service (NHS) in excess of £1 million per annum for routine follow-up appointme...

    Kirstie Pye, Nicola Totton, Nicholas Stuart, Rhiannon Whitaker, Val Morrison, Rhiannon Tudor Edwards, Seow Tien Yeo, Laura J. Timmis, Caryl Butterworth, Liz Hall, Tekendra Rai, Zoe Hoare, Richard D. Neal, Clare Wilkinson and Simon Leeson

    Pilot and Feasibility Studies 2016 2:67

    Published on: 23 November 2016

  21. Study Protocol

    Development and feasibility testing of an intervention to support active lifestyles in youths with type 1 diabetes—the ActivPals programme: a study protocol

    The global incidence of type 1 diabetes is rising, and youths with type 1 diabetes continue to suffer poorer health than peers without diabetes. Evidence suggests youths with type 1 diabetes have physical acti...

    Fiona Mitchell, Alison Kirk, Kenneth Robertson and John J. Reilly

    Pilot and Feasibility Studies 2016 2:66

    Published on: 8 November 2016

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