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Table 5 Median sample size per arm split by condition, study type and intervention type

From: A review of sample sizes for UK pilot and feasibility studies on the ISRCTN registry from 2013 to 2020

 

N

Target sample size

Median (IQR)

Minimum

Maximum

Condition category

 Cancer

72

30 (25, 46)

6

1598

 Circulatory system

72

30 (20, 43)

4

200

 Digestive system

21

25 (16, 30)

10

192

 Ear, nose and throat

6

41 (19, 55)

15

71

 Eye diseases

9

33 (20, 45)

10

50

 Genetic diseases

3

25 (20, 29)

15

32

 Haematological disorders

5

25 (20, 28)

20

65

 Infections and infestations

24

50 (35, 88)

10

350

 Injury, occupational diseases, poisoning

24

25 (15, 33)

10

51

 Mental and behavioural disorders

187

30 (22, 40)

5

602

 Musculoskeletal diseases

55

26 (24, 40)

10

232

 Neonatal diseases

4

57 (35, 87)

20

125

 Nervous system diseases

46

25 (16, 39)

5

383

 Nutritional, metabolic, endocrine

55

30 (20, 49)

10

650

 Oral health

15

36 (20, 65)

10

400

 Pregnancy and childbirth

27

45 (30, 70)

5

175

 Respiratory

37

30 (25, 40)

15

100

 Signs and symptoms

15

30 (20, 42)

5

84

 Skin and connective tissue diseases

9

35 (25, 40)

10

60

 Surgery

15

35 (25, 43)

15

58

 Urological and genital diseases

28

25 (18, 52)

6

400

 Unknown

32

46 (30, 76)

12

350

Study type

 Diagnostic

8

63 (41, 79)

6

125

 Prevention

63

40 (29, 70)

10

650

 Quality of life

67

30 (21, 50)

8

350

 Screening

12

60 (40, 245)

20

1598

 Treatment

568

30 (20, 42)

4

602

 Othera

43

40 (25, 56)

6

140

Intervention type

 Behavioural

231

30 (20, 46)

6

650

 Biological/vaccine

4

17 (14, 27)

10

50

 Device

43

25 (17, 37)

5

200

 Drug

50

30 (20, 57)

12

265

 Mixed

24

29 (20, 60)

10

100

 Procedure/surgery

64

25 (20, 37)

4

232

 Supplement

18

25 (20, 32)

15

100

 Othera

325

30 (24, 50)

5

1598

 Unknown

2

23 (19, 26)

15

30

  1. aOther defined by the study team in the ISRCTN web registry