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Table 3 Studies in the review that satisfy the different sample size recommendations

From: A review of sample sizes for UK pilot and feasibility studies on the ISRCTN registry from 2013 to 2020

Recommendation

Frequency (%)

N = 761

Kieser et al. [11]

Continuous outcomes that have ≥ 10 per arm

 Satisfied

580 (76%)

 Not satisfied

11 (1%)

 Not applicable

170 (22%)

Julious [10]

Continuous outcomes that have ≥ 12 per arm

 Satisfied

563 (74%)

 Not satisfied

28 (4%)

 Not applicable

170 (22%)

Sim and Lewis [12]

Continuous outcomes that have ≥ 28 per arm

 Satisfied

329 (43%)

 Not satisfied

262 (35%)

 Not applicable

170 (22%)

Teare et al. [13]

Continuous outcomes that have ≥ 35 per arm and binary outcomes that have ≥ 60 per arm

 Satisfied

251 (33%)

 Not satisfied

436 (57%)

 Not applicable

74 (10%)

Whitehead et al. [7]

Definitive RCTs with a continuous outcome with a target effect size of:

 Extra small (< 0.1) (≥ 75 per arm)

52 (7%)

 Small (0.1–0.29) (≥ 25 per arm)

389 (51%)

 Medium (0.3–0.69) (≥ 15 per arm)

549 (72%)

 Large (≥ 0.7) (≥ 10 per arm)

580 (76%)

 Not applicable

181 (24%)