Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study

Table 5 Reliable change in plwMND and caregivers from baseline to 6 months

Outcome measure	N	Cronbach's alpha (study ref. no.)	Reliable deterioration (N)	No reliable change (N)	Reliable improvement (N)
plwMND
Quality of life: MQOL-R
Global^a	21	N/A	N/A	N/A	N/A
Physical	21	0.66 [41]	0	21	0
Psychological	21	0.85 [41]	2	16	3
Existential	21	0.78 [41]	0	21	0
Social	21	0.87 [41]	1	19	1
Total score	21	0.94 [41]	4	14	3
Mood: mHADS^b
Depression	18	0.82 [53]	0	17	1
Anxiety	18	0.83 [53]	0	15	3
Health status: EQ-5D-5L index value	21	0.83 [55]	6	15	0
Health status: EQ-VAS^a	21	N/A	N/A	N/A	N/A
Disease-related functioning: ALS FRS-R	21	0.88 [54]	9	11	1
Psychological flexibility: AAQ-II	21	0.84 [44]	3	17	1
Caregivers
Health status: EQ-5D-5L index value	8	0.82 [56]	0	7	1
Health status: EQ-VAS^a	8	N/A	N/A	N/A	N/A
Caregiver burden: ZBI	8	0.93 [57]	3	5	0

One participant who was recruited but later found to be ineligible is not included here
AAQ-II Acceptance and Action Questionnaire-II, ALS FRS-R Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised, CI Confidence interval, EQ-5D-5L. EQ-VAS EQ-Visual Analogue Scale, ES Effect size, mHADS Hospital Anxiety and Depression Scale modified for plwMND such that one depression item and one anxiety item were not scored, as previously recommended [43], MQOL-R McGill Quality of Life Questionnaire-Revised, SD Standard deviation, STTS-R Satisfaction with Therapy and Therapist Scale-Revised, ZBI Zarit Burden Interview
^aMeasures of internal consistency do not apply to single-item measures
^bOne depression item and one anxiety item were not scored on the HADS, as previously recommended [43]

ISSN: 2055-5784