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Table 4 Mean scores, mean change scores and effect sizes at baseline and 6 months

From: Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study

 

Baseline

6 months

Change score (baseline-6 months)

Outcome measure

N

Mean (SD)

N

Mean (SD)

N

Mean (SD)

ES

95% CI

plwMND (N = 29)

 Quality of life: MQOL-R

  Global (possible range 0–10)

29

6.8 (2.2)

21

7.0 (1.7)

21

0.24 (1.79)

0.13

-0.30 to 0.56

  Physical (possible range 0–10)

29

5.8 (2.2)

21

5.5 (1.8)

21

0.67 (1.83)

0.36

-0.08 to 0.80

  Psychological (possible range 0–10)

29

7.0 (2.6)

21

7.6 (2.1)

21

-0.12 (1.87)

-0.06

-0.49 to 0.37

  Existential (possible range 0–10)

29

6.7 (2.3)

21

7.1 (1.8)

21

-0.12 (1.50)

-0.08

-0.51 to 0.35

  Social (possible range 0–10)

29

8.2 (1.9)

21

8.6 (1.5)

21

-0.30 (1.50)

-0.20

-0.63 to 0.23

  Total score (possible range 0–10)

29

6.9 (1.9)

21

7.2 (1.5)

21

0.03 (1.36)

0.02

-0.41 to 0.45

 Mood: mHADSa

  Depression (possible range 0–18)

26

3.4 (3.2)

21

3.0 (2.6)

18

0.06 (2.44)

0.02

-0.44 to 0.48

  Anxiety (possible range 0–18)

26

5.3 (4.0)

21

4.1 (3.0)

18

0.94 (2.62)

0.36

-0.12 to 0.83

  Health status: EQ-5D-5L index value (possible range 0–1)

29

0.6 (0.2)

21

0.5 (0.3)

21

0.13 (0.20)

0.67

0.19 to 1.14

  Health status: EQ-VAS (possible range 0–100)

29

66.3 (25.8)

21

65.0 (21.7)

21

4.86 (19.55)

0.25

-0.19 to 0.68

  Disease-related functioning: ALS FRS-R (possible range 0–48)

29

35.2 (7.6)

21

30.9 (8.1)

21

4.52 (6.65)

0.68

0.20 to 1.15

  Psychological flexibility: AAQ-II (possible range 7–49)

29

17.2 (8.5)

21

17.2 (7.8)

21

-0.52 (8.51)

-0.06

-0.49 to 0.37

 Treatment satisfaction: STTS-R

  Satisfaction with therapy (possible range 6–30)

-

-

19

24.5 (5.0)

-

-

-

-

  Satisfaction with therapist (possible range 6–30)

-

-

19

28.1 (2.3)

-

-

-

-

  Global improvement (possible range 1–5)

-

-

19

2.0 (0.7)

-

-

-

-

 Caregivers (N = 18)

  Health status: EQ-5D-5L index value (possible range 0–1)

17

0.8 (0.3)

9

0.9 (0.1)

8

-0.02 (0.07)

-0.34

-1.04 to 0.39

  Health status: EQ-VAS (possible range 0–100)

17

77.4 (17.4)

9

84.0 (14.8)

8

1.75 (10.63)

0.17

-0.54 to 0.86

  Caregiver burden: ZBI (possible range 0–88)

17

18.9 (14.0)

9

19.2 (15.1)

8

-8.50 (11.30)

-0.75

-1.53 to 0.06

  1. One participant who was recruited but later found to be ineligible is not included here
  2. AAQ-II Acceptance and Action Questionnaire-II: higher scores indicate greater psychological inflexibility, ALS FRS-R Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised: higher scores indicate better disease-related functioning, CI Confidence interval, EQ-5D-5L Higher scores indicate better health status, EQ-VAS EQ-Visual Analogue Scale: higher scores indicate better health status, ES Effect size, mHADS Hospital Anxiety and Depression Scale modified for plwMND such that one depression item and one anxiety item were not scored, as previously recommended [43]: higher scores indicate greater depression or anxiety, MQOL-R McGill Quality of Life Questionnaire-Revised: higher scores indicate better quality of life, SD standard deviation, STTS-R Satisfaction with Therapy and Therapist Scale-Revised: higher scores indicate greater satisfaction with therapy or the therapist; higher scores for global improvement indicate higher perceived improvement, ZBI Zarit Burden Interview: higher scores indicate higher caregiver burden
  3. aOne depression item and one anxiety item were not scored on the HADS, as previously recommended [43]
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Pilot and Feasibility Studies

ISSN: 2055-5784