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Table 2 Secondary outcome measures for assessment of process and performance

From: Team approach to polypharmacy evaluation and reduction: feasibility randomized trial of a structured clinical pathway to reduce polypharmacy

Outcome

Measure or source

Details of measure

Scoring

Quality of life

Short-Form Health Survey (SF36-V1)

• Eight domains: role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health

0 to 100, with higher scores = higher quality of life

EQ5D-5L [51, 52]

• Five domains with 5-point scales: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression

• Overall health rated on scale from 0–100 (“worst imaginable health” to “best imaginable health”)

The Canadian Index was used: -0.148 to 0.949, with higher scores = high quality of life

World Health Organization Disability Assessment Schedule 2.0 (WHODAS) [53]

• Thirty-six items to assess health and disability across all diseases and is useful for multimorbidity

• Six domains of functioning rated as 0–4 (none, mild, moderate, severe, extreme): including cognition, mobility, self-care, getting along, life activities, and participation

Summed the first 36 items

0 to 144, with higher scores representing higher disability

Psychological distress

Kessler Psychological Distress Scale [54]

• Ten items that produce a global measure of distress based on questions about anxiety and depressive symptoms experienced in last 4 weeks

• 5-point scale (all of the time, most of the time, some of the time, a little of the time, and none of the time)

Did not include the question “during the last 30 days, how often did you feel worthless?”

Scores for 9 items range 9 to 45, with higher values representing higher psychological distress

Cognition

Mini-mental status examination (MMSE) [55, 56]

• Eleven items for 5 domains of cognitive function: orientation, registration, attention, calculation, recall, and language

Overall score ranges 0 to 30

Severe impairment = 0 to 9

Moderate impairment = 10 to 19

Mild impairment = 20–25

Potentially normal = 26–30 [57]

Mobility-related fatigue

Avlund Mobility-Tiredness Scale [58]

• Indicated whether participant experiences fatigue performing 6 activities (yes = 1 or no = 0)

0 to 6, with higher scores representing greater fatigue

Mobility

MANTY (64)

• Three items: level of difficulty walking 2 km, walking 0.5 km, and climbing 1 flight of stairs

• Participants indicate the following: manage without great difficulty, some difficulty, a great deal of difficulty, with the help of another person or unable to manage even with help

Descriptive

Nutritional status

Mini Nutritional Assessment Short-Form [59]

• Six items: identifies elderly patients who are malnourished or at risk of being malnourished

• Has been used to measure decline in nutritional status due to polypharmacy (63)

0 to 14, with higher scores indicating a better nutritional status

Sleep

Pittsburgh Sleep Quality Index (65)

• Assesses 1-month period

• Nineteen items grouped into 7 components which are weighted equally on a scale of 0–3

0 to 21, with higher scores indicating poorer sleep quality

Patient enablement

Patient Enablement Instrument (66)

• Six items about patient understanding of and coping with health issues as a result of a consultation with a healthcare provider

• We changed the stem, “As a result of your visit to the doctor today” to “After a usual visit with your family doctor”

0 to 12, with higher scores indicating a stronger patient enablement

Grip strength

With a JAMAR hand dynamometer

• Done with a supported forearm (67) but alternating between right and left hands to prevent fatigue

• Three trials per hand

Average of three trials

Measured in kilograms

Number of falls

Electronic Medical Record

• The number of falls and those requiring medical attention

• The number of health care providers seen by the patient

• The number of visits to the providers related to each fall incident

Descriptive

Healthcare utilization

Electronic medical record

Custom self-report form

• Number of hospitalizations, emergency room visits, or urgent care visits

• Number of long-term care admissions

• Number of family doctor or specialist visits

• Medication use

• Home care services

• Professional care services

• Support equipment use

• Caregiver support

• Home care visits

Descriptive