1. To what extent is implementation of TAPER feasible in a primary care setting? | Categories of outcomes |
What is the recruitment, refusal, and drop-out rate of participants, pharmacists, and family physicians? | Process |
What are the challenges with determining to extent to which participants meet eligibility criteria? | Process |
What is the nature of challenges in terms of participants’ understanding of, and ability to respond to, the surveys? | Process |
What is the nature of any instances of unblinding? | Process |
What is the length of time to complete the surveys? | Resources |
How much travel time does the research team do to complete visits? | Resources |
What is the nature of data entry/database problems? | Management |
What is the nature of any serious adverse events associated with the intervention or study process? | Scientific |
What is the variance, potential floor, and ceiling effects for research outcomes? | Scientific |
2. Is there any emergent evidence of direction of effect of TAPER compared to usual care on a range of potential outcomes? | |
Outcomes include number of medications (potential primary outcome for larger randomized controlled trial), medication dose, quality of life, psychological distress, cognition, mobility-related fatigue, nutritional status, level of mobility functioning, sleep quality, patient enablement, grip strength, falls, healthcare utilization, and adverse events |