Table 2 Exclusion criteria

Present disease or disease history

Autoimmune disease

Inflammatory bowel diseases

Past major abdominal or pelvic surgery

Therapy

Immune-modulating or immunosuppressive

Antibiotics therapy up to three months before enrolment

Feeding-related conditions

Usage of tube feeding

Known or suspected allergy to any treatment or placebo component

Cognitive impairment

Known and established cognitive decline

Any comorbidity preventing reliable completion of trial assessments

Parkinson’s symptoms

Motor fluctuations