Table 2 Characteristics of ASSESS-meso participants who chose not to be considered for future TwiCs. All values given are n (%) unless otherwise stated
Participants who did not wish to be considered for TwiCs | All ASSESS-meso participants | |
|---|---|---|
Total | 4 | 91 |
Male | 3 (75) | 77 (84.6) |
Age, median (range) | 79 (64–93) | 74 (33–93) |
Performance status | ||
0 | 2 (50) | 30 (33.0) |
1 | 2 (50) | 42 (46.2) |
2 | - | 17 (18.7) |
3 | - | 2 (2.2) |
Asbestos exposure | ||
None recalled | - | 14 (15.4) |
Transient | - | 11 (12.1) |
Light/passive | 3 (75) | 20 (22.0) |
Heavy/active | 1 (25) | 46 (50.5) |
Presenting symptoms | ||
Breathlessness | 2 (50) | 72 (79.1) |
Chest pain | 1 (25) | 32 (35.1) |
Cough | 3 (75) | 38 (41.8) |
Sweats | 1 (25) | 12 (13.2) |
Lethargy | - | 20 (22.0) |
Anorexia | - | 11 (12.1) |
Weight loss | 1 (25) | 25 (27.5) |
Asymptomatic | 1 (25) | 3 (3.3) |
Duration of symptoms | ||
< 1 month | 2 (50) | 21 (23.1) |
1–3 months | 1 (25) | 39 (42.9) |
> 3 months | 1 (25) | 28 (30.8) |
Asymptomatic | - | 3 (3.3) |
Method of diagnosis | ||
US-guided biopsy | 1 (25) | 10 (11.0) |
CT-guided biopsy | - | 8 (8.8) |
Medical thoracoscopy | 2 (50) | 46 (50.6) |
VATS | - | 16 (17.6) |
Other biopsy (e.g. laparoscopic) | - | 5 (5.5) |
Cytological | 1 (25) | 4 (4.4) |
Clinico-radiological | - | 2 (2.2) |
Disease site | ||
Pleural | 4 (100) | 88 (96.7) |
Peritoneal | - | 3 (3.3) |
Laterality | ||
Left | 2 (50) | 38 (41.8) |
Right | 2 (50) | 50 (55.0 |
Peritoneal | - | 3 (3.3) |
Tumour histology | ||
Epithelioid | 3 (75) | 72 (79.1) |
Sarcomatoid | - | 10 (11.0) |
Biphasic | - | 2 (2.2) |
Deciduoid | - | 1 (1.1) |
No histology obtained | 1 (25) | 6 (6.6) |
Brims prognostic score | ||
1 (best prognosis) | 2 (50) | 11 (12.1) |
2 | 1 (25) | 33 (36.3) |
3 | 1 (25) | 16 (17.6) |
4 (worst prognosis) | - | 31 (34.1) |