Table 5 Quality of life scores, mean ± SD at baseline, and at the end of the study

Global health status/QoL (QL2)

65.32 ± 17.76

78.23 ± 21.16

9.0; 16.8

 Physical functioning (PF2)

85.59 ± 18.39

91.40 ± 15.98

3.0; 8.6

 Role functioning (RF2)

84.41 ± 26.85

86.02 ± 24.76

−3.5; 6.7

 Emotional functioning (EF)

74.73 ± 23.12

79.03 ± 23.06

−1.1; 9.7

 Cognitive functioning (CF)

89.78 ± 19.09

91.40 ± 15.44

−2.1; 5.3

 Social functioning (SF)

79.57 ± 28.45

82.80 ± 23.76

−1.8; 8.2

 Fatigue (FA)

28.49 ± 24.20

21.86 ± 20.79

−10.0; −3.3

 Nausea (NV)

15.59 ± 18.73

5.38 ± 10.88

−14.0; −6.4

 Pain (PA)

14.52 ± 19.60

13.44 ± 24.50

−5.4; 3.3

 Dyspnoea (DY)

17.20 ± 20.85

15.05 ± 22.51

−5.7; 1.4

 Insomnia (SL)

38.89 ± 31.66

32.26 ± 34.94

−12.4; −0.9

 Appetite loss (AP)

38.89 ± 34.00

22.58 ± 36.91

−22.3; −8.9

 Constipation (CO)

13.98 ± 25.49

18.28 ± 27.00

−3.5; 12.2

 Diarrhoea (DI)

9.68 ± 23.08

6.45 ± 15.91

−9.3; 2.9

 Financial difficulties (FI)

18.28 ± 30.84

15.05 ± 27.00

−10.1; 3.6