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Fig. 3 | Pilot and Feasibility Studies

Fig. 3

From: A feasibility study on yoga’s mechanism of action for chronic low back pain: psychological and neurophysiological changes, including global gene expression and DNA methylation, following a yoga intervention for chronic low back pain

Fig. 3

a PCA plot of top 500 DE methylated genes. PCA plots showing overall differences in methylation levels between the samples. Principal components were computed for top 500 methylated promoters using prcomp() function and top two PCs are plotted. Post and Pre groups do not form distinct separate cluster. b Change in methylation in the Post vs Pre group. Average methylation change in the post-yoga group vs pre-yoga group by genomic position relative to TSS. Changes are averaged over all genes. Negative and postive distances indicate the upstream and downstream regions of TSS. The vertical axis shows base 2 logit differences. c Top DE methylated genes DAVID ontology. Gene ontology analysis for top differentially methylated genes

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Pilot and Feasibility Studies

ISSN: 2055-5784