Table 4 Pre- and post-study drug hematological and coagulation profile. Data are expressed as mean (SD), unless otherwise specified
Prior to study drug | Post-study drug | |||
|---|---|---|---|---|
FEIBA n = 6 | Placebo n = 6 | FEIBA n = 6 | Placebo n = 6 | |
R value, min | 7.78 (1.83) | 6.63 (1.75) | 5.5 (1.29) | 5.17 (1.27) |
K, min | 2.34 (1.99) | 2.35 (0.69) | 2.58 (1.88) | 2.12 (1.21) |
α angle, degrees | 66 (15) | 61 (7) | 65 (12) | 63 (12) |
MA, mm | 53 (13) | 55 (6) | 55 (12) | 60 (6) |
A, mm | 53 (12) | 55 (5.2) | 55 (13) | 59 (5) |
CI | −2.3 (3.9) | −1.6 (2.3) | 0.32 (3.0) | 0.17 (2.8) |
LY 30 | 0.2 (0.3) | 0.03 (0.1) | 0.04 (0.05) | 0.13 (0.33) |
Hematocrit | 27.3 (25.0) | 27.7 (24.4) | 28.6 (22.8) | 29.7 (22.4) |
Platelets | 98 (60) | 114 (25) | 135 (67) | 168 (40) |
INR | 2.2 (0.7) | 1.8 (0.2) | 1.38 (0.3) | 1.50 (0.1) |
aPTT | 48 (23) | 36 (10) | 45 (15) | 35 (5) |
Fibrinogen | 189 (117) | 189 (53) | 220 (104) | 194 (43) |