Brief psychotherapy administered by non-specialised health workers to address risky substance use in patients with multidrug-resistant tuberculosis: a feasibility and acceptability study

Table 2 Changes in primary and secondary outcomes in 26 patients completing the intervention

Questionnaire	Baseline Med (IQR)	Follow-up Med (IQR)
ASSIST^b (alcohol and substance use)
Highest score^a	17.5 (15–24)	6 (6–8)
Alcohol	17.5 (15–23)	6 (6–8)
Cannabis	0 (0–6)	0 (0–6)
Amphetamines	0 (0–0)	0 (0–0)
CES-D (depression)	23.5 (18–34)	17 (13–22)
FTND^c (nicotine dependence)	2 (2–4)	1 (1–2)
EQ-5D 3L (health status
Descriptive elements	5.5 (5–7)	5 (5–5)
Visual analogue scale	70 (57–80)	90 (80–100)
SHS (disability)
Work/school	0 (0–3)	0 (0–0)
Social life	2.5 (0–5)	0 (0–3)
Family life/home responsibilities	4 (0–7)	0 (0–3)
SRQ-20 (psychological distress)	8 (4–10)	3 (1–4)
SOCRATES (readiness for change)
Recognition	20 (19–22)	15 (15–19)
Ambivalence	13 (11–15)	8 (4–10)
Taking steps	35 (32–39)	40 (38–40)
MDSPSS (social support)
Significant other	8 (4–10)	3 (1–4)
Family	7 (6–7)	7 (6–7)
Friends	6 (4–6)	5 (4–6)
Total	6 (5–6)	6 (6–7)

Abbreviations: ASSIST Alcohol, Smoking and Substance Involvement Screening Test, a measure of problematic alcohol and drug use [23], CESD-D Centre for Epidemiological Studies Depression Scale, a measure of the most common symptoms of depression [27], FTND Fagerström Test for Nicotine Dependence, a measure of the intensity of physical addition to nicotine [28], EQ-5D 3L, a standardised instrument combining both descriptive (lower score indicates better health) and visual components as a measure of health outcome [29], SDS Sheehan Disability Scale, a measure of functional impairment in three inter-related domains: work, social and family life [30], SRQ-20 Self-Reporting Questionnaire 20 (SRQ20), a World Health Organisation screening test for anxiety and depression disorders [31], SOCRATES Stages of Change Readiness and Treatment Eagerness Scale, an experimental instrument designed to assess readiness for change [32], and MSPSS Multidimensional Scale of Perceived Social Support, a brief self-report questionnaire with 12 items that subjectively measure perceived social support using three subscales, namely, family, friends and significant others (MSPSS) [33]
^aFour (15%) patient regularly used more than one substance before the intervention; the substance with the highest ASSIST score was used
^bNo patient reported sedative, hallucinogen, opiate or methaqualone use
^cOf the 11 smoking patients who scored > 1 on the Fagerström test at baseline

ISSN: 2055-5784