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Table 3 Summary statistics, mean, standard deviation (SD) and range, and between-group mean differences of the potential primary outcome measures

From: Balance Right in Multiple Sclerosis (BRiMS): a feasibility randomised controlled trial of a falls prevention programme

  Time point Usual care BRiMS Difference between allocated groups
(BRiMS–usual care)
Mean (95% CI)
Minimal clinically important difference (MCID), where available
N Mean (SD)
[Min–max]
N Mean (SD)
[Min–max]
Unadjusted Adjusted
MSWS-12v2a
(range 0–100)
Baseline 26 79.6 (14.4) 30 84.2 (16.2)   Between 4.0 and 6.0 [33]
[52.0–100.0] [45.0–100.0]
Week 15 24 79.8 (13.9) 25 75.6 (19.4) − 4.2 (− 14 to 5.5) − 10.6 (− 18.9 to 2.2)
[48.0–100.0] [33.0–100.0]
Week 27 22 79.5 (21.9) 22 75.4 (16.8) − 4.0 (− 15.9 to 7.8) − 7.7 (− 17.2 to 1.8)
[21.0–100.0] [40.0–100.0]
EQ5D-3Lb
(crosswalk)
Baseline 26 0.58 (0.16) 29 0.54 (0.17)   0.05–0.08 [34]
[0.04–0.77] [− 0.04–0.88]
Week 15 24 0.60 (0.18) 25 0.59 (0.17) − 0.01 (− 0.11 to 0.09) 0.03 (− 0.07 to 0.14)
[0.20–0.91] [− 0.01–0.88]
Week 27 22 0.59 (0.25) 22 0.57 (0.11) − 0.02 (− 0.13 to 0.10) 0.02 (− 0.09 to 0.14)
[− 0.13–0.91] [0.30–0.77]
MSIS-29v2a
(physical)
(range 0–100)
Baseline 26 64.2 (21.7) 30 64.8 (16.4)   8.0 [35]
[25.0–97.0] [32.0–93.0]
Week 15 24 59.4 (23) 25 54.8 (19.5) − 4.6 (− 16.8 to 7.7) − 4.9 (− 13.2 to 3.5)
[13.0–98] [13–92]
Week 27 22 59.0 (24.9) 22 57.9 (15.2) − 1.2 (− 13.7 to 11.4) 0.6 (− 7.8 to 9)
[0.0.–92] [27–88]
MSIS-29v2a (psychological)
(range 0–100)
Baseline 26 45.1 (29.7) 30 50.4 (22.8)   N/A
[0.0–85] [4.0–96]
Week 15 24 43.3 (26.8) 25 43.7 (19) 0.5 (− 12.8 to 13.8) − 5.0 (− 15.5 to 5.5)
[0–89] [0.0–70.0]
Week 27 22 40.0 (26.8) 22 43.3 (22.6) 3.3 (− 11.8 to 18.4) − 0.4 (− 9.9 to 9)
[0.0–93] [7.0–81]
  1. MSWS MS walking scale, MSIS MS impact scale
  2. aDecrease in score indicates improvement
  3. bIncrease in score indicates improvement