Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial

Table 5 Clinically important outcomes

End point	High dose (n = 21)	Usual care (n = 20)	p
PRISM score, median (IQR)^a	5.0 (4.0, 7.0)	7.0 (5.0, 8.5)	0.1
Total fluid intake POD1 to 3 (mL/kg), median (IQR)^b	258 (155,382)	319 (250, 766)	0.10
Hypocalcemia, n (%)	8 (38.1)%	10 (50.0%)	0.44
Received catecholamines, n (%)	11 (52.4%)	15 (75.0%)	0.13
Post-operative arrhythmia, n (%)	5 (23.8%)	10 (50.0%)	0.08
Positive post-operative culture, n (%)	5 (23.8%)	6 (30.0%)	0.66
ARF requiring dialysis, n (%)	2 (9.5%)	7 (35.0%)	0.049
Length of initial MV (h), median (IQR)	7 (6, 46)	41 (9,138)	0.06
Length of MV total (h), median (IQR)	9 (6,52)	77 (17,193)	0.03
PICU length of stay, median (IQR)	3 (1,7)	7 (3.5, 13)	0.10
Hospital length of stay, median (IQR)	8 (4,13)	13.5 (7, 20)	0.11
In-hospital mortality, n (%)	0 (0%)	0 (0%)	–

PRISM Pediatric Risk of Mortality, POD Post-operative day, ARF Acute renal failure, MV Mechanical ventilation, PICU Pediatric intensive care unit
^aFor patients with cyanotic heart disease, PaO₂ was not included in the PRISM score calculation as it is expected that PaO₂ would be low for these patients
^bTotal fluid intake represents the fluid intake over the first 3 post-operative days

ISSN: 2055-5784