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Table 3 Intraoperative and immediate post-operative 25OHD concentrations

From: Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial

Time point (n = high dose, low dose) 25OHD (nmol/L) N (%) VDD
High dose Usual care High dose Usual care
Intraoperative—prior to the initiation of CPB (n = 21, 20) 81.5 (36.5)a 55.5 (13.8) 5 (24%) 7 (35%)
Immediately post-operative at PICU admission (n = 21, 19) 52.0 (23.3)a 34.8 (12.0) 9 (43%) 16 (84%)
POD1 (n = 20, 19) 53.8 (23.5)a 33.0 (17.8) 9 (45%) 15 (79%)
POD3 (n = 9, 16) 55.0 (28.3)a 34.3 (11.5) 4 (44%) 14 (88%)
POD5 (n = 8, 12) 58.3 (38.3) 35.8 (13.5) 4 (50%) 9 (75%)
  1. Data are mean (SD)
  2. CPB Cardiopulmonary bypass, VDD Vitamin D deficiency (25OHD < 50 nmol/L), PICU Pediatric intensive care unit, POD Post-operative day
  3. aSignificantly higher in HD than UC; POD10/discharge 25OHD concentration only obtained for 6 patients, data not shown