|
Tympanometry findings
|
Prednisolone (n = 15)
|
Control (n = 22)
|
Effect estimate (relative risk)
|
p value
|
|---|
|
Complete middle ear effusion resolutiona (n, %)
|
|
Day 3 (visit 1)
|
6 (40)
|
5 (23)
|
1.76 (0.65, 4.73)
|
0.29
|
|
Day 7 (visit 2)
|
8 (53)
|
8 (36)
|
1.47 (0.71, 3.04)
| |
|
Day 30 (visit 3)
|
8 (53)
|
11(50)
|
1.07 (0.57, 2.00)
| |
|
Day 90 (visit 4)
|
12 (80)
|
15 (68)
|
1.17 (0.80, 1.72)
| |
|
Improvement of curve type from baseline visitb (n, %)
|
|
Day 3 (visit 1)
|
7 (47)
|
7 (32)
|
1.47 (0.65, 3.32)
|
0.49
|
|
Day 7 (visit 2)
|
12 (80)
|
10 (45)
|
1.76 (1.04, 2.97)
| |
|
Day 30 (visit 3)
|
10 (67)
|
14 (64)
|
1.05 (0.65, 1.69)
| |
|
Day 90 (visit 4)
|
14 (93)
|
16 (73)
|
1.28 (0.96, 1.71)
| |
|
Improvement of curve type from previous visitc (n, %)
|
|
Day 3 (visit 1)
|
7 (47)
|
7 (32)
|
1.47 (0.65, 3.32)
|
0.49
|
|
Day 7 (visit 2)
|
9 (60)
|
9 (41)
|
1.47 (0.76, 2.81)
| |
|
Day 30 (visit 3)
|
9 (60)
|
13 (59)
|
1.01 (0.59, 1.74)
| |
|
Day 90 (visit 4)
|
13 (87)
|
15 (68)
|
1.27 (0.89, 1.80)
| |
- aComplete resolution is defined as a type A curve in tympanometry examination
- bImprovement of curve type is defined as an improvement from type B curve to type C2, C1, or A curve; or from type C2 curve to type C1 or A curve; or type C1 to A curve; or persisting type A curve at particular time point compared to the baseline
- cImprovement of curve type is defined as an improvement from type B curve to type C2, C1, or A curve; or from type C2 curve to type C1 or A curve; or type C1 to A curve; or persisting type A curve at particular time point compared to the previous visit
