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Table 5 Differences in within-group and between-group differences in secondary outcome measures

From: The efficacy of foot orthoses in individuals with patellofemoral osteoarthritis: a randomised feasibility trial

 

Foot orthoses (n = 12)

Flat insert (n = 11)

 

Baseline

6 weeks

Mean change (6 weeks—baseline)

Baseline

6 weeks

Mean change (6 weeks—baseline)

Foot orthoses—flat inserts adjusted mean difference (95% CI) 6 weeks^

Maximum VAS on most aggravating activity (0 to 100 mm)

51.6 (20.3)

24.6 (26.4)

− 27.0 (22.5)

73.2 (25.3)

66.0 (36.9)

− 7.2 (26.0)

− 21.9 (− 46.0 to 2.1)

Average VAS on most aggravating activity (0 to 100 mm)

39.2 (20.0)

14.5 (16.5)

− 24.7 (22.4)

58.8 (25.8)

38.6 (29.1)

− 20.1 (27.7)

− 15.8 (− 36.6 to 4.9)

AKPS (0 to 100)

62.0 (12.2)

72.5 (17.2)

10.5 (14.6)

46.4 (10.9)

49.1 (21.5)

2.7 (17.9)

9.1 (− 8.6 to 26.8)

KOOS—pain (0 to 100)

67.8 (10.8)

79.4 (13.3)

11.7 (13.8)

54.2 (12.5)

60.0 (20.9)

5.8 (15.3)

8.1 (− 6.9 to 23.1)

KOOS—symptoms (0 to 100)

64.6 (18.3)

67.0 (16.6)

2.4 (10.6)

56.1 (15.1)

56.4 (17.8)

0.3 (14.8)

4.4 (− 6.6 to 15.5)

KOOS—ADL (0 to 100)

80.7 (10.6)

87.7 (14.2)

7.0 (8.6)

59.6 (19.8)

56.1 (21.8)

− 3.5 (15.9)

13.7 (0.2 to 27.2)

KOOS—sport/recreation (0 to 100)

37.1 (20.2)

56.3 (30.4)

19.2 (29.0)

15.0 (11.6)

20.0 (21.3)

5.0 (23.9)

25.7 (− 1.7 to 53.0)

KOOS—QOL (0 to 100)

50.5 (12.9)

62.7 (14.4)

12.2 (11.2)

34.2 (16.1)

37.7 (20.0)

3.5 (13.8)

11.3 (− 1.4 to 24.0)

  1. Patient-reported outcomes are reported both within group to describe change over time and between group (foot orthoses versus flat inserts) for differences at 6 weeks
  2. Values are reported as mean (SD) unless otherwise stated
  3. VAS visual analogue scale (0 = no pain; 100 = worst pain possible), AKPS Anterior Knee Pain Scale (0 = maximal disability; 100 = no disability), KOOS Knee Injury and Osteoarthritis Outcome Score (0 = worst score; 100 = best score), ADL activities of daily living, QOL quality of life
  4. ^ANCOVA analysis of covariance (adjusted for baseline scores)