Fish protein supplementation in older nursing home residents: a randomised, double-blind, pilot study

Table 3 Serum concentration of markers of inflammation and glucose metabolism

	Baseline	Endpoint	Mean difference in change between groups^a
	Mean (SD)	Mean (SD)	Mean (95% CI)
MCP-1, pg/ml
Intervention group	178 (70)	159 (63)	− 80 (− 146, − 13)*
Control group	364 (324)	425 (401)
CRP, mg/l
Intervention group	3.77 (7.68)	6.29 (8.91)	0.77 (− 6.83, 8.37)*
Control group	8.71 (11.50)	10.46 (17.14)
Glucose, mmol/l
Intervention group	5.82 (1.00)	5.77 (1.14)	− 0.02 (− 0.41, 0.38)
Control group	5.59 (0.62)	5.56 (0.62)
Insulin, ng/ml
Intervention group	0.36 (0.13)	0.34 (0.12)	− 0.09 (− 0.23,0.04)
Control group	0.51 (0.42)	0.58 (0.61)
Fructosamine, μmol/l
Intervention group	280 (40)	280 (36)	2.86 (−13.74, 19.46)
Control group	259 (26)	256 (31)

Data is presented as mean and standard deviation with n = 12 in the intervention group and n = 9 in the control group. For serum insulin concentrations, one participant in the intervention group used insulin and was therefore excluded; thus, results are presented for n = 11 in the intervention group and n = 9 in the control group. The groups were similar at baseline (independent samples t test). MCP-1, CRP and insulin were log-transformed prior to testing; within-group changes were tested using paired samples t test, and no significant changes within groups were observed. Within group changes were compared between groups using independent samples t test. p value < 0.05 was considered significant. MCP-1 monocyte chemoattractant protein-1; CRP C-reactive protein; CI confidence interval
^aMean difference in change between groups shows change in control group minus change in intervention group
*Reflects significant differences in mean change between intervention group and control group

ISSN: 2055-5784