Table 2 Between-group comparison of effects of yoga on oxidative status and motor and non-motor functions at 12 weeks adjusting for baseline measurement and l-dopa dose
Variable | Yoga | Wait-list control | Difference | 95% CI |
|---|---|---|---|---|
(n = 10) | (n = 10) | |||
Oxidative status | ||||
↑Total GSH (μg/ml) | 211.4 (7.4) | 207.5 (7.8) | − 3.9 (10.9) | (− 26.8, 19.0) |
↑GSH:GSSG ratio | 12.4 (.7) | 13.1 (.7) | 0.6 (1) | (− 1.5, 2.7) |
↓MDA (μM) | 42.7 (4.6) | 46.5 (4.9) | 3.8 (6.9) | (− 10.7, 18.3) |
↓SOD (U/ml) | 375.9 (37.5) | 485.7 (39.5) | 109.8 (55) | (− 6, 225) |
↑Catalase (nmol/min/ml) | 41,826 (3045) | 42,583 (3249) | 757 (4936) | (− 9613, 11,127) |
↓Protein carbonyl (nmol/ml) | 17 (2) | 19.2 (2.1) | 2.1 (3) | (− 4.2, 8.4) |
↑GPx (nmol/min/ml/mg) | 16.2 (1.6) | 15.3 (1.7) | − 0.8 (2.3) | (− 5.6, 4.0) |
Motor function | ||||
↓Motor UPDRS (0–108) | 17 (1.7) | 22.5 (1.8) | 5.4 (2.6) | (− 0.1, 10.9) |
↑LAPAQ level, in minutes | 2563 (756) | 5749 (800) | 3187 (1141) | (790, 5584) |
QOS and QOL (range of scores) | ||||
↑PD Sleep Scale (0–150) | 112.2 (4.1) | 106.3 (4.3) | − 5.8 (6) | (− 18.4, 6.8) |
↑MoCA (0–30) | 28.1 (.4) | 27.5(.4) | − 0.8 (.6) | (− 2.1, 0.5) |
↓Beck Depression Inventory (0–63) | 8.9 (1.1) | 8.6 (1.2) | − 0.3 (1.7) | (− 3.9, 3.3) |
↓PDQUALIF | ||||
Social and role function (0–100) | 44 (3.8) | 41.8 (4) | −2.2 (5.6) | (−14.0, 9.6) |
Self-image and sexuality (0–100) | 37.6 (3.9) | 41.5 (4.1) | 3.8 (5.8) | (− 8.4, 16.0) |
Sleep (0–100) | 35.1 (3.1) | 24.7 (3.3) | − 10.4 (4.6) | (− 20.1, − 0.7) |
Outlook (0–100) | 45.8 (2.9) | 35.2 (3) | − 10.6 (4.3) | (− 19.6, − 1.6) |
Physical functioning (0–100) | 33.9 (3.2) | 36.2 (3.4) | 2.3 (4.7) | (− 7.6, 12.2) |
Independence (0–100) | 10 (5) | 5.4 (5.3) | − 4.5 (7.4) | (− 20.0, 11.0) |
Urinary function (0–100) | 50.8 (4.9) | 47.7 (5.3) | − 3 (7.7) | (− 19.2, 13.2) |
Global (0–100) | 52 (6.3) | 53.3 (6.6) | 1.2 (9.3) | (− 18.3, 20.7) |