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Table 2 Baseline/pre-operative/operative/post-operative variables

From: Measuring skin necrosis in a randomised controlled feasibility trial of heat preconditioning on wound healing after reconstructive breast surgery: study protocol and statistical analysis plan for the PREHEAT trial

Baseline variables:

Age (years), ethnicity, height, weight, diabetic, hypertensive, smoker, smoking history, BRCA carrier, neoadjuvant therapy, previous breast surgery on study breast, type of previous breast surgery, oncological reason for mastectomy, prophylactic reason for mastectomy.

Pre-operative variables:

Pre-operative variables: measurement notch to nipple, inframammary fold to nipple, breast cup size, sensory changes, sensory changes due to, degree of breast ptosis, type of reconstruction (implant/autologous based) study breast.

Operative variables:

Surgery (yes/no), reason for no surgery if no, breast surgeon, plastic surgeon, side of study breast, type of construction, type of mastectomy, surgical technique for mastectomy, infiltration used, type of breast reconstruction, axillary clearance, core temperature pre first incision, environmental temperature pre first incision, mastectomy skin flap thickness (for upper outer, lower outer, lower inner, upper inner quadrants), mastectomy skin flap thickness measurement method, mastectomy breast weight, reconstruction flap weight, implant/expander volume, type of implant used, core temperature post reconstruction, environmental temperature post reconstruction, number of drains, duration of operation, intra-operative complications.

Additional post-operative outcomes:

Wound infection additional antibiotic course, type of antibiotic given, post-operative seroma, seroma required draining, site drainage of the seroma performed, method to detect seroma, post-operative haematoma required surgery, surgical intervention for complications of reconstruction, surgical re-intervention for reconstruction complication, repeated surgical interventions.