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Table 3 Criteria for clinical response evaluation [2022]

From: Immediate tumor resection in patients with locally advanced gastroesophageal adenocarcinoma with nonresponse to chemotherapy after 4 weeks of treatment versus resection after completion of chemotherapy (OPTITREAT trial, DRKS00004668): study protocol for a randomized controlled pilot trial

 

Endoscopy

 

Endoscopic ultrasound

 

Others

Responder

Major reduction of tumor size (>75 %) with significant flattening of the tumor

and

More than 50 % reduction of wall thickness (at the largest tumor diameter)

Nonresponder

Visible residual tumor

and/or

Less than 50 % reduction of wall thickness (at the largest tumor diameter)

and/or

Metastatic lesions