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Table 3 Sample size estimation based on changes in handgrip strength

From: NOURISH, Nutritional OUtcomes from a Randomised Investigation of Intradialytic oral nutritional Supplements in patients receiving Haemodialysis: a pilot randomised controlled trial

Minimum clinically important difference (kg) 80% power 85% power 90% power 95% power
2 450 515 603 745
4 113 129 151 187
6 50 58 67 83
10 18 21 25 30
  1. Type 1 error of 0.05 and standard deviation of 10.705 (calculated from this pilot sample). Increase by 20% to account for dropout rate.