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Table 3 Sample size estimation based on changes in handgrip strength

From: NOURISH, Nutritional OUtcomes from a Randomised Investigation of Intradialytic oral nutritional Supplements in patients receiving Haemodialysis: a pilot randomised controlled trial

Minimum clinically important difference (kg)

80% power

85% power

90% power

95% power

2

450

515

603

745

4

113

129

151

187

6

50

58

67

83

10

18

21

25

30

  1. Type 1 error of 0.05 and standard deviation of 10.705 (calculated from this pilot sample). Increase by 20% to account for dropout rate.