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  1. Conduct disorder (CD) is a complex mental disorder characterized by severe rule-breaking and aggressive behavior. While studies have shown that several therapeutic interventions are effective in treating CD sy...

    Authors: Svenja Taubner, Sophie Hauschild, Lea Kasper, Michael Kaess, Esther Sobanski, Thorsten-Christian Gablonski, Paul Schröder-Pfeifer and Jana Volkert
    Citation: Pilot and Feasibility Studies 2021 7:139
  2. Evidence for interventions promoting oral health amongst care home residents is weak. The National Institute for Health and Care Excellence (NICE) guideline NG48 aims to maintain and improve the oral health of...

    Authors: Georgios Tsakos, Paul R. Brocklehurst, Sinead Watson, Anna Verey, Nia Goulden, Alison Jenkins, Zoe Hoare, Kirstie Pye, Rebecca R. Wassall, Andrea Sherriff, Anja Heilmann, Ciaran O’Neill, Craig J. Smith, Joe Langley, Renato Venturelli, Peter Cairns…
    Citation: Pilot and Feasibility Studies 2021 7:138
  3. Uncontrolled bleeding after cardiac surgery can be life-threatening. Factor eight inhibitor bypassing activity (FEIBA) is a prothrombin complex concentrate empirically used as rescue therapy for correction of ...

    Authors: Valerie A. Sera, Ann E. Stevens, Howard K. Song, Victor M. Rodriguez, Frederick A. Tibayan and Miriam M. Treggiari
    Citation: Pilot and Feasibility Studies 2021 7:137
  4. Evidence about contextual interference in children with brain lesions when practising motor tasks is lacking. Our main objective was to evaluate the feasibility of a randomised controlled trial (RCT) comparing...

    Authors: Judith V. Graser, Caroline H. G. Bastiaenen, Anja Gut, Urs Keller and Hubertus J. A. van Hedel
    Citation: Pilot and Feasibility Studies 2021 7:135
  5. Low back pain (LBP) is a long-term health condition with an unpredictable pattern of symptomatic episodes, remission, and recurrence. Recently published systematic reviews suggest that exercise is the most eff...

    Authors: Luciana G. Macedo, Julie Richardson, Michele C. Battie, Mark Hancock, Matthew Kwan, Genevieve Hladysh and Linda Zhuo
    Citation: Pilot and Feasibility Studies 2021 7:134
  6. Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the age of the menopause. Whilst the relationship bet...

    Authors: Ioana R. Marian, Megan Goff, Jennifer A. E. Williams, Malvika Gulati, Mae Chester-Jones, Anne Francis, Marion Watson, Tonia L. Vincent, Sue Woollacott, Charles Mackworth-Young, Victoria Glover, Dominic Furniss, Matthew Gardiner, Sarah E. Lamb, Katy Vincent, Vicki S. Barber…
    Citation: Pilot and Feasibility Studies 2021 7:133
  7. The World Health Organization recommends that community health workers (CHWs) receive a mix of financial and non-financial incentives, yet notes that there is limited evidence to support the use of one type of...

    Authors: Thomas Gadsden, Stephen Jan, Sujarwoto Sujarwoto, Budiarto Eko Kusumo and Anna Palagyi
    Citation: Pilot and Feasibility Studies 2021 7:132
  8. The severity of performance fatigability and the capacity to recover from activity are profoundly influenced by skeletal muscle energetics, specifically the ability to buffer fatigue-inducing ions produced fro...

    Authors: Liana C. Wooten, Brian T. Neville and Randall E. Keyser
    Citation: Pilot and Feasibility Studies 2021 7:131
  9. Post-traumatic headaches (PTH) are a common sequelae of traumatic brain injury (TBI) and greatly impact patient function and quality of life. Post-traumatic greater occipital neuralgia (GON) is a type of post-...

    Authors: Jacqueline E. Stone, Tak S. Fung, Matthew Machan, Christina Campbell, Rodney Li Pi Shan and Chantel T. Debert
    Citation: Pilot and Feasibility Studies 2021 7:130
  10. Behavioral weight loss interventions promote clinically significant weight loss over 12 months, but weight regain remains problematic and a substantial proportion of participants do not achieve long-term weigh...

    Authors: Suzanne Phelan, Sapna Peruvemba, David Levinson, Noah Stulberg, Aidan Lacy, Maria Legato and James P. Werner
    Citation: Pilot and Feasibility Studies 2021 7:129
  11. Hand fractures are common and sometimes require surgery to restore function. Placement of Kirschner wires (K-wires) is the most common form of surgical fixation. After placement, a key decision is whether to b...

    Authors: Justin Conrad Rosen Wormald, Mark Medhat Mikhail, Jeremy Neil Rodrigues, Sonya Gardiner, Theodore Pezas, Hawys Lloyd-Hughes, Fadi Issa, Abhilash Jain and Matthew David Gardiner
    Citation: Pilot and Feasibility Studies 2021 7:128
  12. Patients with end-stage kidney disease who receive haemodialysis experience a protracted treatment regimen that can result in an increased risk of depression and anxiety. Arts-based interventions could address...

    Authors: Claire Elizabeth Carswell, Joanne Reid, Ian Walsh, William Johnston, Jenny B. Lee, Helen McAneney, Robert Mullan, Hugh Nelson, Michael Matthews, Elizabeth Weatherup, Andrea Spencer, Jean Michelo, Anne Quail, Grainne Kielty, Alistair Mackenzie, Jenny Elliott…
    Citation: Pilot and Feasibility Studies 2021 7:127
  13. Although rarely indicated, antibiotics are commonly used for acute diarrhoea in China. We conducted a randomised, double blind exploratory clinical trial of loperamide, berberine and turmeric for treatment of ...

    Authors: Yanhong Jessika Hu, Xudong Zhou, Shanjuan Wang, Merlin Willcox, Colin Garner, David Brown, Taeko Becque, Beth Stuart, Zongru Han, Qin Chang, Michael Moore and Paul Little
    Citation: Pilot and Feasibility Studies 2021 7:126

    The Correction to this article has been published in Pilot and Feasibility Studies 2021 7:159

  14. Effective sex education is the key to good sexual health. Peer-led approaches can augment teacher-delivered sex education, but many fail to capitalise on mechanisms of social influence. We assessed the feasibi...

    Authors: Kirstin R. Mitchell, Carrie Purcell, Sharon A. Simpson, Chiara Broccatelli, Julia V. Bailey, Sarah J. E. Barry, Lawrie Elliott, Ross Forsyth, Rachael Hunter, Mark McCann, Lisa McDaid, Kirsty Wetherall and Laurence Moore
    Citation: Pilot and Feasibility Studies 2021 7:125
  15. Ear disease is a major cause of preventable hearing loss and is very common in rural communities, estimated to affect 1.3 million Australians. Rural community pharmacists are well placed to provide improved ea...

    Authors: Selina Maree Taylor, Alice Cairns, Efi Mantzourani and Beverley D. Glass
    Citation: Pilot and Feasibility Studies 2021 7:124
  16. Robust measurement of dietary intake in population studies of children is critical to better understand the diet–health nexus. It is unknown whether parent proxy-report of children’s dietary intake through onl...

    Authors: Isobel Sharpe, Sharon I. Kirkpatrick, Brendan T. Smith, Charles D. G. Keown-Stoneman, Jessica Omand, Shelley Vanderhout, Jonathon L. Maguire, Catherine S. Birken and Laura N. Anderson
    Citation: Pilot and Feasibility Studies 2021 7:123
  17. The ABLE intervention was developed to enhance the ability to perform activities of daily living (ADL) tasks among persons living with chronic conditions. ABLE is a generic, home-based, individualised, 8-week ...

    Authors: Vita Hagelskjær, Kristina Tomra Nielsen, Cecilie von Bülow, Maud Graff and Eva Ejlersen Wæhrens
    Citation: Pilot and Feasibility Studies 2021 7:122
  18. The majority of stroke survivors experience motor impairment which benefits from rehabilitation treatment. Telerehabilitation, remote delivery of rehabilitation services, is a possible solution providing acces...

    Authors: Sue Peters, Marcela Botero, Allison Evers, Brianna Fong, Botond Jakab, Emily Petter and Janice J. Eng
    Citation: Pilot and Feasibility Studies 2021 7:121
  19. Adolescents with disability are less active and have lower levels of physical fitness than their typically developing peers. Schools are ideal settings to address this; however, few school-based interventions ...

    Authors: Angus A. Leahy, Sarah G. Kennedy, Jordan J. Smith, Narelle Eather, James Boyer, Matthew Thomas, Nora Shields, Ben Dascombe and David R. Lubans
    Citation: Pilot and Feasibility Studies 2021 7:120
  20. It is unclear whether how people with long-term conditions express distress, and how clinicians respond, influences perceptions of consultation outcomes. The pilot study examined emotional distress and reassur...

    Authors: Niall C. Anderson, Yuefang Zhou and Gerry Humphris
    Citation: Pilot and Feasibility Studies 2021 7:119
  21. This protocol is for a feasibility study of a mindfulness-based stress reduction (MBSR) program adapted for pregnant women with psychosocial vulnerabilities. The rationale for the study is the need for a wider...

    Authors: S. Skovbjerg, D. Birk, S. Bruggisser, A. L. A. Wolf and L. Fjorback
    Citation: Pilot and Feasibility Studies 2021 7:118
  22. Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset of Parkinson’s disease (PD) patients that is poorly responsive to standard levodopa therapy or deep brain stimulation (DBS) ...

    Authors: Stephano J. Chang, Iahn Cajigas, James D. Guest, Brian R. Noga, Eva Widerström-Noga, Ihtsham Haq, Letitia Fisher, Corneliu C. Luca and Jonathan R. Jagid
    Citation: Pilot and Feasibility Studies 2021 7:117
  23. People with serious mental illnesses (SMI) such as schizophrenia often also have physical health illnesses and interventions are needed to address the resultant multimorbidity and reduced life expectancy. Rese...

    Authors: Julie Williams, Elliann Fairbairn, Ray McGrath, Ioannis Bakolis, Andy Healey, Ubong Akpan, Isabel Mdudu, Fiona Gaughran, Euan Sadler, Zarnie Khadjesari, Kate Lillywhite and Nick Sevdalis
    Citation: Pilot and Feasibility Studies 2021 7:116
  24. After a traumatic brain injury, disturbances in the attentional processes have a direct negative effect on functional recovery and on return to complex activities. To date, there is no good attention remediati...

    Authors: Ève Boissonnault, Johanne Higgins, Geneviève LaGarde, Dorothy Barthélemy, Céline Lamarre and Jehane H. Dagher
    Citation: Pilot and Feasibility Studies 2021 7:115
  25. Sleep disturbances are challenging symptoms associated with mild cognitive impairment or dementia (MCIoD). This study assessed the feasibility of sleep monitoring and non-pharmacological interventions to impro...

    Authors: Rosemary Gibson, Anthony Dowell, Linda Jones and Philippa Gander
    Citation: Pilot and Feasibility Studies 2021 7:114
  26. Development of physical literacy, defined as “the motivation, confidence, physical competence, knowledge and understanding to value and take responsibility for engagement in physical activities for life,” can ...

    Authors: Cassandra Lane, Valerie Carson, Kayla Morton, Kendra Reno, Chris Wright, Madison Predy and Patti-Jean Naylor
    Citation: Pilot and Feasibility Studies 2021 7:113
  27. Children are vulnerable to the effects of second-hand smoke exposure. Creating smoke-free homes is an effective strategy to limit exposure. We developed a smoke-free intervention (SFI) using children as a cata...

    Authors: Cath Jackson, Rumana Huque, Farid Ahmed, Shammi Nasreen, Sarwat Shah, Jasjit S. Ahluwalia, Mona Kanaan, Aziz Sheikh and Kamran Siddiqi
    Citation: Pilot and Feasibility Studies 2021 7:112
  28. We have co-designed a tailored blended physiotherapy intervention for people with progressive multiple sclerosis (PwPMS) who often struggle to access support for physical activity. Underpinned by self-manageme...

    Authors: Julie Latchem-Hastings, Elizabeth Randell, Kate Button, Fiona Jones, Rachel Lowe, Helen Dawes, Fiona Wood, Freya Davies, Vincent Poile, Rhian O’Halloran, Barbara Stensland, Emma Tallantyre, Rebecca Playle, Adrian Edwards and Monica Busse
    Citation: Pilot and Feasibility Studies 2021 7:111
  29. Adolescent mothers in Zimbabwe often experience stigma, isolation, and lack coping skills and resources to successfully navigate motherhood. Social isolation and stigma are linked to poor mental health outcome...

    Authors: Chiwoneso B. Tinago, Edward A. Frongillo, Andrea M. Warren, Vivian Chitiyo, Ashley K. Cifarelli, Shannon Fyalkowski and Victoria Pauline
    Citation: Pilot and Feasibility Studies 2021 7:110
  30. Cognitive behavioural therapy (CBT) is the most widely recognised and efficacious psychological therapy for the treatment of anxiety disorders in children and adults. However, suboptimal remission rates indica...

    Authors: Samantha Galea, Chloe A. Salvaris, Marie B. H. Yap, Peter J. Norton and Katherine A. Lawrence
    Citation: Pilot and Feasibility Studies 2021 7:109
  31. Falls prevention exercise programmes help to improve muscle strength, balance and physical function, and reduce falling rates in older adults. Improvements in muscle strength, balance and physical function are...

    Authors: Sarah Audsley, Denise Kendrick, Pip Logan and Elizabeth Orton
    Citation: Pilot and Feasibility Studies 2021 7:108
  32. Practitioners frequently use informed consent forms to support the physician-patient communication and the informed consent process. Informed consent for surgery often focuses on risk centered information due ...

    Authors: Alina Weise, Julia Lühnen, Stefanie Bühn, Felicia Steffen, Sandro Zacher, Julia Lauberger, Deha Murat Ates, Andreas Böhmer, Henning Rosenau, Anke Steckelberg and Tim Mathes
    Citation: Pilot and Feasibility Studies 2021 7:107
  33. Aboriginal people face challenges on several fronts when it comes to the health and wellbeing of their community, compared to the rest of the Australian population. This is no different in urban areas such as ...

    Authors: Ashley Ubrihien, Kylie Gwynne and David A. Lewis
    Citation: Pilot and Feasibility Studies 2021 7:106
  34. There is a lack of functional performance measures for children and young people with haemophilia (CYPwH) with associated control data from typically developing boys (TDB). The literature advocates development...

    Authors: Nicola Thorpe, Phillip Harniess, Eleanor Main, Nicola Hubert, Sarah Rand, David Stephensen, Ri Liesner and Melanie Bladen
    Citation: Pilot and Feasibility Studies 2021 7:105
  35. Repetitive transcranial magnetic stimulation (rTMS) is a technique for stimulating brain activity using a transient magnetic field to induce an electrical current in the brain producing depolarization of focal...

    Authors: Xiao Wei Tan, Edimansyah Abdin and Phern Chern Tor
    Citation: Pilot and Feasibility Studies 2021 7:104
  36. Chronic spontaneous urticaria is a common disorder that is poorly understood and frequently misdiagnosed. Psychological difficulties are a significant factor in dermatological diseases and may also aggravate s...

    Authors: Katie Ridge, Niall Conlon, Martina Hennessy and Pádraic J. Dunne
    Citation: Pilot and Feasibility Studies 2021 7:103

    The Correction to this article has been published in Pilot and Feasibility Studies 2021 7:136

  37. Authors: Caroline B. Hing, Elizabeth Tutton, Toby O. Smith, Molly Glaze, Jamie R. Stokes, Jonathan Cook, Melina Dritsaki, Emma Phelps, Cushla Cooper, Alex Trompeter, Michael Pearse, Michael Law and Matthew L. Costa
    Citation: Pilot and Feasibility Studies 2021 7:102

    The original article was published in Pilot and Feasibility Studies 2021 7:93

  38. Moderate to severe anxiety disorders such as obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social phobia and panic disorder are common, and affect approximately 11–16% of women in...

    Authors: Fiona L. Challacombe, Laura Potts, Ben Carter, Vanessa Lawrence, Alaina Husbands and Louise M. Howard
    Citation: Pilot and Feasibility Studies 2021 7:101
  39. Compared to the rest of Europe, the UK has relatively poor cancer outcomes, with late diagnosis and a slow referral process being major contributors. General practitioners (GPs) are often faced with patients p...

    Authors: Stefanie Disbeschl, Alun Surgey, Jessica L. Roberts, Annie Hendry, Ruth Lewis, Nia Goulden, Zoe Hoare, Nefyn Williams, Bethany Fern Anthony, Rhiannon Tudor Edwards, Rebecca-Jane Law, Julia Hiscock, Andrew Carson-Stevens, Richard D. Neal and Clare Wilkinson
    Citation: Pilot and Feasibility Studies 2021 7:100
  40. Fatigue interference with activities, mood, and cognition is one of the most prevalent and bothersome concerns of advanced gastrointestinal (GI) cancer patients. As fatigue interferes with patient functioning,...

    Authors: Catherine E. Mosher, Ekin Secinti, Kurt Kroenke, Paul R. Helft, Anita A. Turk, Patrick J. Loehrer Sr, Amikar Sehdev, Ahmad A. Al-Hader, Victoria L. Champion and Shelley A. Johns
    Citation: Pilot and Feasibility Studies 2021 7:99
  41. Cervical cancer is the leading cause of cancer incidence and mortality among Malawian women, despite being a largely preventable disease. Implementing a cervical cancer screening and preventive treatment (CCSP...

    Authors: Jennifer H. Tang, Jennifer S. Smith, Shannon McGue, Luis Gadama, Victor Mwapasa, Effie Chipeta, Jobiba Chinkhumba, Erik Schouten, Bagrey Ngwira, Ruanne Barnabas, Mitch Matoga, Maganizo Chagomerana and Lameck Chinula
    Citation: Pilot and Feasibility Studies 2021 7:98
  42. Given the high risk of infectious mortality among children with severe acute malnutrition (SAM), the World Health Organization recommends routine administration of a broad-spectrum antibiotic like amoxicillin ...

    Authors: Kieran S. O’Brien, Ali Sié, Clarisse Dah, Millogo Ourohire, Ahmed M. Arzika, Valentin Boudo, Elodie Lebas, William W. Godwin, Benjamin F. Arnold and Catherine E. Oldenburg
    Citation: Pilot and Feasibility Studies 2021 7:97
  43. Pilot and feasibility studies (PAFS) often have complex objectives aimed at assessing feasibility of conducting a larger study. These may not be clear to participants in pilot studies.

    Authors: Mohammed I.U. Khan, Lawrence Mbuagbaw, Matthew Holek, Faris Bdair, Zoha H. Durrani, Katie Mellor, Saskia Eddy, Sandra M. Eldridge, Claire L. Chan, Michael J. Campbell, Christine M. Bond, Sally Hopewell, Gillian A. Lancaster and Lehana Thabane
    Citation: Pilot and Feasibility Studies 2021 7:96
  44. Chronic pain is a poorly managed symptom of inflammatory bowel disease (IBD). Cognitive behavioural therapy (CBT) has an evidence base in functional gastrointestinal conditions and chronic pain. This study aim...

    Authors: Louise Sweeney, Rona Moss-Morris, Wladyslawa Czuber-Dochan and Christine Norton
    Citation: Pilot and Feasibility Studies 2021 7:95
  45. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Laura Williams, Charlotte L. Hall, Susan Brown, Boliang Guo, Marilyn James, Matilde Franceschini, Julie Clarke, Kim Selby, Hena Vijayan, Neeta Kulkarni, Nikki Brown, Kapil Sayal, Chris Hollis and Madeleine J. Groom
    Citation: Pilot and Feasibility Studies 2021 7:94

    The original article was published in Pilot and Feasibility Studies 2021 7:68

  46. Segmental tibial fractures are fractures in two or more areas of the tibial diaphysis resulting in a separate intercalary segment of the bone. Surgical fixation is recommended for patients with segmental tibia...

    Authors: Caroline B. Hing, Elizabeth Tutton, Toby O. Smith, Molly Glaze, Jamie R. Stokes, Jonathan Cook, Melina Dritsaki, Emma Phelps, Cushla Cooper, Alex Trompeter, Michael Pearse, Michael Law and Matthew L. Costa
    Citation: Pilot and Feasibility Studies 2021 7:93

    The Correction to this article has been published in Pilot and Feasibility Studies 2021 7:102

  47. Plantar heel pain (PHP) is common and impacts negatively on physical function and quality of life. Initial treatment usually comprises analgesia and self-management advice (SMA), with referral to a physiothera...

    Authors: Linda S. Chesterton, Martin J. Thomas, Gordon Hendry, Ying Chen, David Goddin, Nicola Halliday, Sarah A. Lawton, Martyn Lewis, Christian D. Mallen, Hylton B. Menz, Nadine E. Foster and Edward Roddy
    Citation: Pilot and Feasibility Studies 2021 7:92
  48. A feasibility study was conducted to implement the Talk, Instruct, Practice, Plan and Support (TIPPS) intervention for pregnant women to enhance infant birth weight in a conflict area in Low- and Middle-Income Co...

    Authors: Lamis Abuhaloob, Nahla Helles, Peter Mossey and Ruth Freeman
    Citation: Pilot and Feasibility Studies 2021 7:91
  49. Intensive care unit (ICU) survivors often suffer from cognitive, physical and mental impairments, known as post-intensive care syndrome (PICS). ICU follow-up clinics may improve aftercare of these patients. Th...

    Authors: M. Rohr, S. Brandstetter, C. Bernardi, C. Fisser, K. P. Drewitz, V. Brunnthaler, K. Schmidt, M. V. Malfertheiner and C. J. Apfelbacher
    Citation: Pilot and Feasibility Studies 2021 7:90

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