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  1. Content type: Study Protocol

    Increases in life expectancy have resulted in a global rise in dementia prevalence. Dementia is associated with poor wellbeing, low quality of life and increased incidence of mental health difficulties such as...

    Authors: Paul Farrand, Joanne Woodford, David Llewellyn, Martin Anderson, Shanker Venkatasubramanian, Obioha C. Ukoumunne, Anna Adlam and Chris Dickens

    Citation: Pilot and Feasibility Studies 2016 2:42

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  2. Content type: Study Protocol

    Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure in the UK. The introduction of techniques to augment the subpectoral pocket has revolutionised the procedure, ...

    Authors: Shelley Potter, Elizabeth J. Conroy, Paula R. Williamson, Steven Thrush, Lisa J. Whisker, Joanna M Skillman, Nicola L. P. Barnes, Ramsey I. Cutress, Elizabeth M. Teasdale, Nicola Mills, Senthurun Mylvaganam, Olivier A. Branford, Katherina McEvoy, Abhilash Jain, Matthew D. Gardiner, Jane M. Blazeby…

    Citation: Pilot and Feasibility Studies 2016 2:41

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  3. Content type: Study Protocol

    Head and neck cancer (HNC) is the sixth most common cancer worldwide, and the functional, psychological and social consequences of HNC cancer and its treatment can be severe and chronic. Dysphagia (swallowing ...

    Authors: Mary Wells, Emma King, Kate Toft, Fiona MacAulay, Joanne Patterson, Nadine Dougall, Nick Hulbert-Williams, Sally Boa, Eleanor Slaven, Julie Cowie, John McGarva, Patricia Gail Niblock, Julie Philp and Justin Roe

    Citation: Pilot and Feasibility Studies 2016 2:40

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  4. Content type: Study Protocol

    African-Caribbeans in the UK have the highest schizophrenia incidence and greatest inequity in access to mental health services of all ethnic groups. The National Institute for Health and Care Excellence (NICE...

    Authors: Dawn Edge, Amy Degnan, Sarah Cotterill, Katherine Berry, Richard Drake, John Baker, Christine Barrowclough, Adwoa Hughes-Morley, Paul Grey, Dinesh Bhugra, Patrick Cahoon, Nicholas Tarrier, Shôn Lewis and Kathryn Abel

    Citation: Pilot and Feasibility Studies 2016 2:39

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  5. Content type: Study Protocol

    Major depressive disorder is a common debilitating illness that is the second leading contributor to the global burden of disease. Unfortunately, about 30 % of patients do not respond to adequate trials of ant...

    Authors: Martha Finnegan, Karen Ryan, Enda Shanahan, Andrew Harkin, Leslie Daly and Declan M. McLoughlin

    Citation: Pilot and Feasibility Studies 2016 2:38

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  6. Content type: Research

    We aimed to establish the support needs of people with heart failure and their caregivers and develop an intervention to improve their health-related quality of life.

    Authors: Colin J. Greaves, Jennifer Wingham, Carolyn Deighan, Patrick Doherty, Jennifer Elliott, Wendy Armitage, Michelle Clark, Jackie Austin, Charles Abraham, Julia Frost, Sally Singh, Kate Jolly, Kevin Paul, Louise Taylor, Sarah Buckingham, Russell Davis…

    Citation: Pilot and Feasibility Studies 2016 2:37

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  7. Content type: Study Protocol

    Clinical practice guidelines advocate engaging stroke survivors in as much activity as possible early after stroke. One approach found to increase activity levels during inpatient rehabilitation incorporated a...

    Authors: Ingrid C. M. Rosbergen, Rohan S. Grimley, Kathryn S. Hayward, Katrina C. Walker, Donna Rowley, Alana M. Campbell, Suzanne McGufficke, Samantha T. Robertson, Janelle Trinder, Heidi Janssen and Sandra G. Brauer

    Citation: Pilot and Feasibility Studies 2016 2:36

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  8. Content type: Research

    Self-care practices in heart failure (HF) contribute to quality of life, symptom stabilization, and extended life expectancy. However, adherence to practices such as liquid and salt restriction or symptom moni...

    Authors: Sylvie Cossette, Hayet Belaid, Sonia Heppell, Tanya Mailhot and Marie-Claude Guertin

    Citation: Pilot and Feasibility Studies 2016 2:34

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  9. Content type: Study Protocol

    Neck pain in adults is common and a leading cause of physical disability. Recently, a guideline was developed for the management of non-specific neck pain (NSNP) with an aim to improve the quality of the deliv...

    Authors: Prakash Dhopte, Sara Ahmed, Nancy Mayo, Simon French, Jeffrey A. Quon and André Bussières

    Citation: Pilot and Feasibility Studies 2016 2:33

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  10. Content type: Research

    Approximately 95 million children worldwide are disabled; 10 % use a wheelchair. In the UK, an estimated 770,000 children are disabled. National Health Service Wheelchair Services are the largest provider of w...

    Authors: Nathan Bray, Seow Tien Yeo, Jane Noyes, Nigel Harris and Rhiannon Tudor Edwards

    Citation: Pilot and Feasibility Studies 2016 2:32

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  11. Content type: Letter

    The National Institute for Health Research (NIHR) has identified a gap in the number of people it funds who are on a pathway to become future leaders of clinical trials, compared to how much the NIHR invests i...

    Authors: Peter Thompson, James Fenton, Lisa Cotterill and James P. Neilson

    Citation: Pilot and Feasibility Studies 2016 2:31

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  12. Content type: Study Protocol

    Prolonged sitting, an independent risk factor for disease development and premature mortality, is increasing in prevalence in high- and middle-income countries, with no signs of abating. Adults in such countri...

    Authors: Eleni Mantzari, Katrien Wijndaele, Soren Brage, Simon J. Griffin and Theresa M. Marteau

    Citation: Pilot and Feasibility Studies 2016 2:30

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  13. Content type: Study Protocol

    There are 7000 new cases of head and neck squamous cell cancers (HNSCC) treated by the NHS each year. Stage III and IV HNSCC can be treated non-surgically by radio therapy (RT) or chemoradiation therapy (CRT)....

    Authors: Vinidh Paleri, Joshua Wood, Joanne Patterson, Deborah D. Stocken, Mike Cole, Luke Vale, Jeremy Franks, Teresa Guerrero-Urbano, Rachael Donnelly, Stewart Barclay, Tim Rapley and Nikki Rousseau

    Citation: Pilot and Feasibility Studies 2016 2:29

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  14. Content type: Study Protocol

    In recent years, university counseling and mental health services have reported an increase in the number of clients seeking services and in yearly visits. This trend has been observed at many universities, in...

    Authors: Patricia Frazier, Derek Richards, Jacqueline Mooney, Stefan G. Hofmann, Deborah Beidel, Patrick A. Palmieri and Christopher Bonner

    Citation: Pilot and Feasibility Studies 2016 2:28

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  15. Content type: Study Protocol

    Handgrip strength is a non-invasive marker of muscle strength, and low grip strength in hospital inpatients is associated with poor healthcare outcomes including longer length of stay, increased functional lim...

    Authors: Kinda Ibrahim, Carl May, Harnish P. Patel, Mark Baxter, Avan A. Sayer and Helen Roberts

    Citation: Pilot and Feasibility Studies 2016 2:27

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  16. Content type: Study Protocol

    Childhood obesity is a major public health problem, with one third of America’s children classified as either overweight or obese. Obesity prevention and health promotion programs using components such as well...

    Authors: Brooke J. Cull, Sara K. Rosenkranz, David A. Dzewaltowski, Colby S. Teeman, Cassandra K. Knutson and Richard R. Rosenkranz

    Citation: Pilot and Feasibility Studies 2016 2:26

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  17. Content type: Methodology

    Feasibility and pilot studies are essential components of planning or preparing for a larger randomized controlled trial (RCT). They are intended to provide useful information about the feasibility of the main...

    Authors: Lehana Thabane, Sally Hopewell, Gillian A. Lancaster, Christine M. Bond, Claire L. Coleman, Michael J. Campbell and Sandra M. Eldridge

    Citation: Pilot and Feasibility Studies 2016 2:25

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    The Erratum to this article has been published in Pilot and Feasibility Studies 2016 2:35

  18. Content type: Research

    Few studies have examined the effectiveness of community-based self-management interventions in older adults with type 2 diabetes mellitus (T2DM) and multiple chronic conditions (MCC). The objectives of this s...

    Authors: Maureen Markle-Reid, Jenny Ploeg, Kathryn Fisher, Holly Reimer, Sharon Kaasalainen, Amiram Gafni, Andrea Gruneir, Ross Kirkconnell, Sam Marzouk, Noori Akhtar-Danesh, Lehana Thabane, Carlos Rojas-Fernandez and Ross Upshur

    Citation: Pilot and Feasibility Studies 2016 2:24

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  19. Content type: Study Protocol

    Head and neck cancer survivors commonly experience severe long-term toxicities, late-occurring symptoms, and significant risks of the second primary malignancy and comorbid illnesses. With multiple simultaneou...

    Authors: Talya Salz, Mary S. McCabe, Kevin C. Oeffinger, Stacie Corcoran, Andrew J. Vickers, Andrew L. Salner, Ellen Dornelas, Rebecca Schnall, Nirupa J. Raghunathan, Elizabeth Fortier and Shrujal S. Baxi

    Citation: Pilot and Feasibility Studies 2016 2:23

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  20. Content type: Study Protocol

    Children whose families are involved with child welfare services manifest disproportionately high levels of behavioral difficulties, which could be addressed in community-based organizations providing services...

    Authors: Geetha Gopalan

    Citation: Pilot and Feasibility Studies 2016 2:21

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  21. Content type: Research

    Depression is associated with a loss of productivity and noticeable personal, social, and economic decline; it affects more than 350 million people worldwide. Behavioral activation (BA), derived from cognitive...

    Authors: Zainab Samaan, Brittany B. Dennis, Lindsay Kalbfleisch, Herman Bami, Laura Zielinski, Monica Bawor, Kathryn Litke, Kathleen McCabe, Jeff Whattam, Laura Garrick, Laura O’Neill, Terri Ann Tabak, Scott Simons, Sandra Chalmers, Brenda Key, Meredith Vanstone…

    Citation: Pilot and Feasibility Studies 2016 2:22

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  22. Content type: Methodology

    Obesity is commonly seen in the Australian general practice population; however, few resources are specifically targeted at GPs working with these patients. The National Health and Medical Research Council (Au...

    Authors: Elizabeth Ann Sturgiss and Kirsty Douglas

    Citation: Pilot and Feasibility Studies 2016 2:20

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  23. Content type: Study Protocol

    Neoadjuvant chemotherapy is a standard of care for patients with adenocarcinoma of the esophagus and stomach in Europe, but still only 20–40 % respond to therapy and the critical issue; how to treat nonrespond...

    Authors: Susanne Blank, Phillip Knebel, Georg-Martin Haag, Thomas Bruckner, Ulla Klaiber, Maria Burian, Anja Schaible, Leila Sisic, Thomas Schmidt, Markus K. Diener and Katja Ott

    Citation: Pilot and Feasibility Studies 2016 2:18

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  24. Content type: Study Protocol

    It is hypothesized that the grieving process of relatives of missing persons is complicated by having to deal with uncertainty about the fate of their loved one. We developed a cognitive behavioural therapy (C...

    Authors: Lonneke I. M. Lenferink, Ineke Wessel, Jos de Keijser and Paul A. Boelen

    Citation: Pilot and Feasibility Studies 2016 2:19

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  25. Content type: Review

    Many complex intervention trials fail to show an intervention effect. Although this may be due to genuine ineffectiveness, it may also be the result of sub-optimal intervention design, implementation failure o...

    Authors: Sara Levati, Pauline Campbell, Rachael Frost, Nadine Dougall, Mary Wells, Cam Donaldson and Suzanne Hagen

    Citation: Pilot and Feasibility Studies 2016 2:17

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  26. Content type: Study Protocol

    Care for seniors is complex because patients often have more than one disease, one medication, and one physician. It is a key challenge for primary care physicians to structure the various aspects of each pati...

    Authors: Birgitta Weltermann and Christine Kersting

    Citation: Pilot and Feasibility Studies 2016 2:16

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  27. Content type: Study Protocol

    Worldwide hip fractures are projected to increase from 1.7 million in 1990 to 6.3 million in 2050. In India, conservative estimates suggest an annual incidence of 600,000 osteoporotic hip fractures and this is...

    Authors: Lalit Yadav, Abha Tewari, Anil Jain, Beverley Essue, David Peiris, Mark Woodward, Prakash Kotwal, Richard Lindley, Stephen Jan, Tracey Chantler, Premila Webster, Robyn Norton and Santosh Rath

    Citation: Pilot and Feasibility Studies 2016 2:15

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  28. Content type: Research

    We investigate in this feasibility study whether specific lip movements increase prenatally when hearing a particular sound. We hypothesised that fetuses would produce more mouth movements resembling those req...

    Authors: Nadja Reissland, Brian Francis, Louisa Buttanshaw, Joe M. Austen and Vincent Reid

    Citation: Pilot and Feasibility Studies 2016 2:14

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  29. Content type: Study Protocol

    Childhood dental anxiety is very common, with 10–20 % of children and young people reporting high levels of dental anxiety. It is distressing and has a negative impact on the quality of life of young people an...

    Authors: Zoe Marshman, Annie Morgan, Jenny Porritt, Ekta Gupta, Sarah Baker, Cathy Creswell, Tim Newton, Katherine Stevens, Christopher Williams, Suneeta Prasad, Jennifer Kirby and Helen Rodd

    Citation: Pilot and Feasibility Studies 2016 2:13

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  30. Content type: Research

    Few evidence-based physical activity interventions for pre-school children are available. This two-armed pilot cluster randomised controlled trial aimed to evaluate the feasibility of conducting a full-scale t...

    Authors: Sally E. Barber, Cath Jackson, Catherine Hewitt, Hannah R. Ainsworth, Hannah Buckley, Shaheen Akhtar, Daniel D. Bingham, Ash C. Routen, Carolyn Summerbell, Gerry Richardson, Helen J. Moore, Kate E. Pickett, Claire O’Malley, Shirley Brierley and John Wright

    Citation: Pilot and Feasibility Studies 2016 2:12

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  31. Content type: Research

    Evidence suggests acupuncture may be effective for treating the symptoms of knee osteoarthritis. Offering this in a group setting may offer cost savings. The aim of this study was to establish the feasibility ...

    Authors: Adrian White, Liz Tough, Vicky Eyre, Jane Vickery, Anthea Asprey, Cath Quinn, Fiona Warren, Colin Pritchard, Nadine E. Foster, Rod S. Taylor, Martin Underwood and Paul Dieppe

    Citation: Pilot and Feasibility Studies 2016 2:10

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  32. Content type: Research

    Exposure to secondhand smoke (SHS) in the antenatal and postnatal period is associated with a detrimental health impact to the foetus and newborn baby and is recognised as a preventable public health challenge...

    Authors: Rachel Mann, Heather Thomson, Becky Reynolds, Amanda Amos and Kamran Siddiqi

    Citation: Pilot and Feasibility Studies 2016 2:9

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  33. Content type: Research

    The use of formative research as a critical component of intervention planning is highly supported in the literature. However, studies that report such processes in practice are minimal. This paper reports on ...

    Authors: Emily Joy Haas, Dana Willmer and Andrew B. Cecala

    Citation: Pilot and Feasibility Studies 2016 2:6

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  34. Content type: Study Protocol

    Stage I non-small cell lung cancer (NSCLC) is potentially curable, and surgery is considered to be the standard of care for patients with good performance status and minimal co-morbidity. However, a significan...

    Authors: M. P. Snee, L. McParland, F. Collinson, C. M. Lowe, A. Striha, D. R. Baldwin, B. Naidu, D. Sebag-Montefiore, W. M. Gregory, J. Bestall, J. Hewison, S. Hinsley and K. Franks

    Citation: Pilot and Feasibility Studies 2016 2:5

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    The Erratum to this article has been published in Pilot and Feasibility Studies 2016 2:55

  35. Content type: Study Protocol

    The transition from adolescence to adulthood is a ‘high-risk’ period for weight gain in the general population. There is speculation that this may also be a risk period for adults with intellectual disabilitie...

    Authors: Fiona Mitchell, Andrew Jahoda, Catherine Hankey, Lynsay Matthews, Heather Murray and Craig Melville

    Citation: Pilot and Feasibility Studies 2016 2:8

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  36. Content type: Study Protocol

    Protected engagement time (PET) is a concept of managing staff time on mental health inpatient wards with the aim of increasing staff and patient interaction. Despite apparent widespread use of PET, there rema...

    Authors: Fiona M. Nolan, Chris Fox, Richard Cheston, David Turner, Allan Clark, Emily Dodd, Mary-Ellen Khoo and Richard Gray

    Citation: Pilot and Feasibility Studies 2016 2:7

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  37. Content type: Research

    Ifosfamide, an alkylating agent used widely in the treatment of childhood malignancy, can cause many side effects including a proximal tubulopathy. Studies suggest that aminoaciduria is seen most commonly of a...

    Authors: Jessica E. Morgan, Karl McKeever, Kay S. Tyerman, Michael Henderson, Susan Picton and Robert S. Phillips

    Citation: Pilot and Feasibility Studies 2016 2:4

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  38. Content type: Research

    Mindfulness-based interventions have shown to improve depression and anxiety symptoms as well as quality of life in patients with inflammatory bowel disease (IBD). However, little is known about the experience...

    Authors: Mariyana Schoultz, Leah Macaden and Gill Hubbard

    Citation: Pilot and Feasibility Studies 2016 2:3

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  39. Content type: Study Protocol

    Physical activity levels are low amongst adolescent girls, and this population faces specific barriers to being active. Peer influences on health behaviours are important in adolescence and peer-led interventi...

    Authors: Simon J. Sebire, Mark J. Edwards, Rona Campbell, Russell Jago, Ruth Kipping, Kathryn Banfield, Keeley Tomkinson, Kirsty Garfield, Ronan A. Lyons, Joanne Simon, Peter S. Blair and William Hollingworth

    Citation: Pilot and Feasibility Studies 2016 2:2

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  40. Content type: Study Protocol

    Falls among hospitalised patients impose a considerable burden on health systems globally and prevention is a priority. Some patient-level interventions have been effective in reducing falls, but others have n...

    Authors: Satyan R. Chari, Simon Smith, Alison Mudge, Alex A Black, Mariana Figueiro, Muhtashimuddin Ahmed, Mark Devitt and Terry P. Haines

    Citation: Pilot and Feasibility Studies 2016 2:1

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  41. Content type: Research

    The blood pressure rapid intensive lowering and normal treatment for mood and cognition in persistent depression (BRILiANT mood study) was devised as a pilot study to investigate the feasibility and safety of ...

    Authors: Kirsty Olsen, Denise Howel, Robert Barber, Gary A. Ford, Peter Gallagher, R. Hamish McAllister-Williams, Jonna Nilsson, John O’Brien, Jennie Parker and Alan Thomas

    Citation: Pilot and Feasibility Studies 2015 1:44

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  42. Content type: Study Protocol

    The aim of this study is to examine the feasibility of a future definitive randomised controlled trial of Family Focused Treatment for Adolescents UK (FFT-A UK) in the management of early-onset bipolar disorde...

    Authors: Joanne Neely, David Miklowitz, Ann Le Couteur, Vicky Ryan, Luke Vale, Ruth McGovern and Aditya Sharma

    Citation: Pilot and Feasibility Studies 2015 1:43

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  43. Content type: Research

    A study to determine the feasibility of conducting a future population-based trial into a self-management intervention for community-living adults with early stage dementia included evaluation of intervention ...

    Authors: Kirsty Sprange, Gail A. Mountain, Katy Shortland, Claire Craig, Daniel Blackburn, Peter Bowie, Kirsty Harkness and Maggie Spencer

    Citation: Pilot and Feasibility Studies 2015 1:42

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  44. Content type: Study Protocol

    Intake of free sugars in the population exceeds recommendations, with the largest source in the diet being sugar-sweetened beverages (SSBs). SSB consumption is linked to adverse health consequences and contrib...

    Authors: Eleni Mantzari, Gareth J. Hollands, Rachel Pechey, Susan Jebb and Theresa M. Marteau

    Citation: Pilot and Feasibility Studies 2015 1:41

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  45. Content type: Study Protocol

    Dementia prevalence is increasing as populations live longer, with no cure and the costs of caring exceeding many other conditions. There is increasing evidence for modifiable risk factors which, if addressed ...

    Authors: Catherine A. O’Donnell, Susan Browne, Maria Pierce, Alex McConnachie, Kay Deckers, Martin P. J. van Boxtel, Valeria Manera, Sebastian Köhler, Muriel Redmond, Frans R. J. Verhey, Marjan van den Akker, Kevin Power and Kate Irving

    Citation: Pilot and Feasibility Studies 2015 1:40

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  46. Content type: Study Protocol

    Depression is a common disorder with a lifetime prevalence of 16 %. Despite the availability of several treatment options for depression, many patients do not respond to treatment and develop chronic illness a...

    Authors: Zainab Samaan, Kathryn Litke, Kathleen McCabe, Brittany Dennis, Jeff Whattam, Laura Garrick, Laura O’Neill, Terri Ann Tabak, Scott Simons, Sandra Chalmers, Brenda Key, Meredith Vanstone, Feng Xie, Gordon Guyatt and Lehana Thabane

    Citation: Pilot and Feasibility Studies 2015 1:39

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  47. Content type: Study Protocol

    The One Health approach is emerging in response to the development of bacterial resistance. To the best of our knowledge, the possibility to use this approach in a clinical context has not yet been explored. T...

    Authors: Gloria Cordoba, Tina Møller Sørensen, Anne Holm, Charlotte Reinhard Bjørnvad, Lars Bjerrum and Lisbeth Rem Jessen

    Citation: Pilot and Feasibility Studies 2015 1:38

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  48. Content type: Editorial

    This editorial introduces a new special series on intervention development in the on-line open access journal Pilot and Feasibility Studies. An intervention development study reports the rationale, decision-makin...

    Authors: Pat Hoddinott

    Citation: Pilot and Feasibility Studies 2015 1:36

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