Comparing mixed oil to soybean oil lipid emulsion in patients on home parenteral nutrition: a pilot prospective double-blind, crossover, randomized trial

Table 4 Clinical outcomes and complications in the 6-month period on each lipid solution in per-protocol population

	SO		MO		SO-MO
	N with data^b	N (%)	N with data^b	N (%)	Difference^a (95% CI)
Total, N	12		12
New CRBSI	12	0 (0.0)	12	0 (0.0)	N/A
New infections including CRSBI	12	4 (33.3)	12	3 (25.0)	0.08 (− 0.20–0.36)
Change of vascular access	12	3 (25.0)	12	1 (8.3)	0.17 (− 0.15–0.48)
Use of antibiotics	12	6 (50.0)	12	2 (16.7)	0.33 (− 0.02–0.69)
Duration antibiotics therapy (days) LS Mean	12	4.39 (6.99)	11	0.17 (2.11)	4.22 (− 0.84–9.28)
Uexpected hospitalization	12	2 (16.7)	12	2 (16.7)	0.00 (− 0.33–0.33)
Surgery	12	1 (8.3)	12	0 (0.0)	N/A
Death	12	0 (0.0)	12	0 (0.0)	N/A
Adverse event	12	6 (50.0)	12	4 (33.3)	0.17 (− 0.29–0.62)
Serious adverse event	12	0 (0.0)	12	1 (8.3)	N/A
Serious adverse event probably related to the intervention	12	0 (0.0)	12	0 (0.0)	N/A

N/A since no statistics were computed if no clinical outcomes or complications occurred for both treatments
Abbreviations: SO Soybean oil, MO Mixed oil, CRBSI Catheter-related bloodstream infection
^aRisk difference for all the binary outcomes and mean difference for duration antibiotics therapy
^bNumber of participants who completed the study with at least one episode of events was counted

ISSN: 2055-5784