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Table 3 Potential treatment effect of MO lipid to SO lipid use on the lipid profile and fatty acid levels in the per-protocol population

From: Comparing mixed oil to soybean oil lipid emulsion in patients on home parenteral nutrition: a pilot prospective double-blind, crossover, randomized trial

Outcomes

Ā 

Least squares mean change from baselineb

Difference in mean change (SO-MO)

na

SO

MO

Least squares mean (95% CI)

Lipid profile

ā€ƒTotal cholesterol (mmol/L)

9

0.10

0.10

0.00 (āˆ’ā€‰0.65ā€“0.66)

ā€ƒTriglycerides (mmol/L)

11

0.20

0.36

ā€‰āˆ’ā€‰0.16 (āˆ’ā€‰0.56ā€“0.24)

Fatty acid profile

ā€ƒLinoleic acid Ļ‰-6

9

49.46

ā€‰āˆ’ā€‰123.00

172.16 (āˆ’ā€‰5.62ā€“349.94)

ā€ƒAlpha linolenic acid (Ļ‰-3)

9

1.81

ā€‰āˆ’ā€‰2.91

4.72 (0.47ā€“8.97)

ā€ƒEicosapentaenoic acid (EPA Ļ‰-3)

9

ā€‰āˆ’ā€‰9.89

50.16

ā€‰āˆ’ā€‰60.05 (āˆ’ā€‰74.72ā€“ā€‰āˆ’ā€‰45.39)

ā€ƒDocosahexaenoic acid (DHA Ļ‰-3)

9

ā€‰āˆ’ā€‰12.1

73.80

ā€‰āˆ’ā€‰85.92 (āˆ’ā€‰158.99ā€“ā€‰āˆ’ā€‰12.85)

ā€ƒRatio Ļ‰-6ā€“Ļ‰-3

8

ā€‰āˆ’ā€‰2.38

ā€‰āˆ’ā€‰0.79

ā€‰āˆ’ā€‰1.59 (āˆ’ā€‰11.37ā€“8.20)

ā€ƒArachidonich acid

9

39.38

ā€‰āˆ’ā€‰98.60

138.01 (āˆ’ā€‰64.47ā€“340.49)

  1. Abbreviations: SO Soybean oil, MO Mixed oil
  2. aNumber of participants with all four measurements at baseline and months 6, 7, and 13
  3. bBaseline is defined as the time at study start for the first arm and month 7 for the second arm