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Fig. 1 | Pilot and Feasibility Studies

Fig. 1

From: The PerPAIN trial: a pilot randomized controlled trial of personalized treatment allocation for chronic musculoskeletal pain—a protocol

Fig. 1

Intervention scheme/trial flow. Note: the same treatment interventions are applied in personalized as well as in non-personalized interventional study arms. However, the arms differ in the assignment to the respective treatment modules: While in the personalized assignment arms patients with high level of emotional distress receive an emotional distress-tailored intervention (EDDT), patients with high avoidance/maladaptive-learning behaviour receive an extinction/retraining-tailored treatment intervention (PERT) and patients with neutral risk profile receive a low-level diary intervention (EMDI), patients in the non-personalized arm receive a non-personalized intervention (i.e. patients with a high level of emotional distress receive either extinction/retraining-tailored or a low-level-tailored intervention, but not the emotional distress-tailored treatment). CMSP, chronic musculoskeletal pain; PERT, Pain Extinction and Retraining-Tailored Intervention; EDDT, Emotional distress desensitization and reprocessing-tailored intervention; EMDI, Ecological Momentary-tailored Low-Level Diary Intervention

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