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Table 10 Sample size calculation scenarios

From: An external pilot cluster randomised controlled trial of a theory-based intervention to improve appropriate polypharmacy in older people in primary care (PolyPrime)

Reduction in PIP (%)

Cluster size

ICC

Loss to follow-up (%)

Total sample size

No. of clusters

10

20

0.01

20

997

50

10

20

0.025

20

1236

62

15

20

0.01

20

479

24

15

20

0.025

20

594

30

  1. ICC intraclass correlation coefficient, PIP potentially inappropriate prescribing