Fig. 1

CONSORT flow diagram for the PolyPrime study. GPP, general practitioner practice; IQR, interquartile range. ^aThe number of patients screened for eligibility relates to 8 GPPs as information was not available for 4 GPPs. ^bThe number of patients contacted and consented relates to 10 GPPs as two GPPs withdrew from the study after randomisation but before baseline data collection and before any details on patient numbers could be obtained. ^cOne intervention arm GPP withdrew from the study, and patients did not receive any medication reviews; however, 3 patients were followed up for the patient-reported outcome questionnaires. ^dAn additional patient withdrew consent from study, but the primary outcome data were collected prior to withdrawal