Table 1 Eligibility and exclusion criteria

• Age ≥ 70

• Living at home

• Having a caregiver/relative and/or supervision at home, or by a friend or partner, not necessarily living in the same building

• Barthel Index ≥ 90 [29]

• Have at least 1 criterion from Fried’s criteria

• Inadequate home infrastructure to host the required technology

• Inability to understand how to use the POSITIVE system

• Diseases that may affect prescription therapy: acute myocardial infarction in the last 3 months, unstable angina, aortic dissection, severe aortic stenosis, endocarditis/acute pericarditis, acute thromboembolic disease, acute heart failure, orthostatic hypotension (uncontrolled), recent fracture in the last month, terminal disease (< 12 months of life expectancy), other pathologies involving clinical instability

• Psychiatric disorders that may potentially interfere in the clinical trial

• History of alcohol/drugs abuse

• Living with another participant,

• Participating in other clinical studies

• Three or more hospitalisations in the last year