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Fig. 2 | Pilot and Feasibility Studies

Fig. 2

From: A feasibility study on yoga’s mechanism of action for chronic low back pain: psychological and neurophysiological changes, including global gene expression and DNA methylation, following a yoga intervention for chronic low back pain

Fig. 2

a Volcano plot. Volcano plots comparing Log2 (fold change) of read count values for the post-yoga group vs the pre-yoga group. Significantly upregulated and downregulated genes at the threshold of (adj pval < 0.1, log2FC > 1) are shown in red. b PCA plot of top 500 DE genes. PCA plots showing overall differences in expression between the samples. Principal components were computed for top 500 differentially expressed genes using prcomp() R function and top two PCs are plotted. Four replicate samples (1, 2, 5, 6) from the Post group cluster together. The first dimension, PC1, separates the four Post samples from the rest of the samples

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