The feasibility and acceptability of a home-based, virtual exercise intervention for older patients with hepatocellular carcinoma: protocol for a non-randomised feasibility study (TELEX-Liver Cancer)

Table 1 Feasibility outcomes for this study

Outcome	Definition
Recruitment rate	The proportion of eligible patients who are approached and give informed consent to participate
Retention rate^a	The proportion of patients who consent to take part in the study and complete the FACT-Hep questionnaire at both baseline and 10-week follow-up
Intervention adherence^b	i) The mean proportion of exercise sessions attended by patients (assessed by attendance records kept by the intervention facilitator) ii) The mean proportion of exercise sessions completed at or above a moderate intensity, assessed via RPE (rating of ≥ 3 on the 10-point scale)
Intervention fidelity	Assessed by a research team member attending a 10% sample of the virtual exercise sessions using a standardised checklist to check whether the sessions are delivered in accordance with the protocol
Safety	The number and type (i.e. serious or non-serious) of adverse events that are related or possibly related to the intervention or study procedures

^aThe Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) questionnaire was chosen for the assessment of retention rate because this is likely to be our primary outcome for a subsequent randomised controlled trial
^bAdherence to the intervention will be evaluated only in patients who complete the study, defined as patients who complete the FACT-Hep questionnaire at both baseline and 10-week follow-up

ISSN: 2055-5784