Table 4 Preliminary efficacy results

Outcome

n

Baseline

6 months

Mean Change

95% Confidence Interval

d

Hippocampal volume (mm³)

DIET

5

3336 ± 557

3338 ± 506

2 ± 139

ED

7

3156 ± 262

3166 ± 291

10 ± 90

Between group difference

8

(-164 to 179)

.11

RAVLT

DIET

7

9.00 ± 1.91

10.57 ± 2.51

1.57 ± 3.10

ED

7

9.86 ± 2.27

10.57 ± 2.15

.71 ± 1.50

Between group difference

.86

(-2.11 to 3.82)

.35

HbA1c (%)

DIET

5

6.00 ± 0.29

5.52 ± 0.18

-.48 ± .19

ED

7

5.76 ± 0.57

5.71 ± 0.55

-.05 ± .05

Between group difference

.43

(.20 to .67)

1.02

Vitamin K (nmol/L)

DIET

5

1.24 ± 0.39

1.45 ± 1.24

.21 ± .88

ED

7

2.65 ± 1.61

1.93 ± 0.98

-.90 ± 1.25

Between group difference

1.11

(-.26 to 2.48)

.70

BEI score (out of 14)

DIET

7

6.43 ± 1.06

9.36 ± 1.28

2.93 ± 1.13

ED

7

7.21 ± 1.60

7.07 ± 1.67

-.14 ± 2.19

Between group difference

3.07

(.96 to 5.18)

1.75

V̇O_2peak (ml/kg/min)

DIET

5

22.16 ± 5.35

24.20 ± 5.82

2.04 ± .88

ED

6

20.13 ± 3.64

22.53 ± 3.23

2.40 ± 2.81

Between group difference

.36

(-3.31 to 2.59)

.17