Skip to main content

Table 2 Participant characteristics at baseline

From: Feasibility and preliminary efficacy of the LEAD trial: a cluster randomized controlled lifestyle intervention to improve hippocampal volume in older adults at-risk for dementia

Demographics

DIET (n = 7)

ED (n = 7)

Age (years)

72 (5)

71 (6)

Sex

4 females (57%)

6 females (86%)

Education (years)

18 (2.5)

13 (2.7)

Early MCI

1 (14%)

2 (29%)

MoCA (out of 30)

27.4 (3.1)

26.3 (3.1)

Body Mass Index (kg/m2)

29.0 (5.0)

30.1 (5.1)

Overweight (n)

5 (71%)

6 (86%)

Hypertension (n)

5 (71%)

4 (57%)

High Cholesterol (n)

4 (57%)

4 (57%)

Pre-diabetes (n)

3 (43%)

0 (0%)

Type 2 Diabetes (n)

1 (14%)

1 (14%)

V̇O2peak (mL kg−1 min−1)

22.16 (5.35)a

20.13 (3.64)b

BEI diet score

6.43 (1.06)

7.21 (1.60)

Hippocampal volume (mm3)

3336 (557)a

3156 (262)

RAVLT scores (out of 15)

9.00 (1.91)

9.86 (2.27)

HbA1c (%)

6.00 (.29)a

5.76 (.57)

Serum vitamin K (nmol/L)

1.24 (0.39)a

2.65 (1.61)

  1. All data are reported in mean (SD) or frequency (%). MCI mild cognitive impairment, MoCA Montreal Cognitive Assessment, V̇O2peak peak oxygen uptake, HbA1c hemoglobin A1c, BEI Brain-healthy Eating Index. Overweight = BMI > 25; hypertension, high cholesterol and type 2 diabetes were physician diagnosed
  2. a5 participants
  3. b6 participants. Participant feedback