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Table 2 Intraoperative characteristics

From: Sugammadex, neostigmine and postoperative pulmonary complications: an international randomised feasibility and pilot trial

Characteristic

Sugammadex (n = 59)

Neostigmine (n = 61)

Surgical urgency

 Elective

58 (98.3)

60 (98.4)

 Expedited

1 (1.7)

1 (1.6)

Surgical incision

 Thoracic

13 (22.0)

10 (16.4)

 Upper abdominal

19 (32.2)

22 (36.1)

 Lower abdominal

27 (45.8)

29 (47.5)

Surgical approach

 Laparoscopic/thoracoscopic

32 (54.2)

31 (50.8)

 Laparoscopic/thoracoscopic assisted

7 (11.9)

8 (13.1)

 Open

20 (33.9)

22 (36.1)

Anaesthetic maintenance

 Propofol

7 (11.9)

10 (16.4)

 Volatile

46 (78.0)

47 (77.0)

 Propofol + volatile

6 (10.2)

4 (6.6)

Antiemetic prophylaxis

51 (86.4)

53 (86.9)

Regional analgesia

17 (28.8%)

18 (29.5%)

Neuromuscular blocking drug

 Rocuronium

49 (83.1)

49 (80.3)

 Vecuronium

10 (16.9)

13 (21.3)

Neuromuscular monitoring

 Quantitative ± qualitative

28 (47.5)

26 (42.6)

 Qualitative alone

27 (45.8)

28 (45.9)

 No monitoring

4 (6.8)

7 (11.5)

Extubated in operating room

57 (96.6)

61 (100.0)

TOF count at reversal

2.0 (2.0–4.0)

4.0 (2.0–4.0)

Sugammadex

56 (94.9)

2 (3.3)

 Dose (mg)

200 (200–200)

200 (0.0–200.0)

Neostigmine

-

59 (96.7)

 Dose (mg)

-

2.5 (2.5–2.5)

TOF ratio at extubation

1.04 (0.94–1.10)

0.93 (0.88–1.00)

Time from reversal to extubation (min)

9.0 (5.5–14.0)

10.0 (7.0–17.0)

Further reversal

-

9 (15.0)

Sugammadex

-

5 (55.6)

Neostigmine

-

4 (44.4)

Duration of anaesthesia (h)

3.8 (2.8–5.4)

4.0 (2.7–5.0)

  1. Results are presented as median (interquartile range) and number (percent). TOF train of four. Missing data: TOF count = 19 (15.8%), TOF ratio = 32 (26.7%), time from reversal to extubation = 3 (2.5%) and further reversal = 3 (2.5%). Of 59 participants randomised to sugammadex, 2 were not extubated and 1 received no reversal. Of 61 participants randomised to neostigmine, 2 were administered sugammadex