Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson’s disease: preliminary cost-consequence analysis of the PD COMM pilot randomised controlled trial

Table 8 Group comparisons: sensitivity of outcome measures to differences between patient groups at baseline

	Severity^a Difference (95% CI)	Speech impacts on social activities^b Difference (95% CI)
VHI	8.8 (− 1.7, 19.4)	28 (17, 38)*
PDQ-39 Summary	10.1 (3.7, 16.6)*	14.9 (7.8, 21.9)*
PDQ_COMM	14.1 (4.7, 23.6)*	21.7 (10.9, 32.4)*
EQ-5D-3L	− 0.20 (− 0.31, − 0.10)*	− 0.11 (− 0.25, 0.04)
ICECAP-O	− 0.01 (− 0.1, 0.08)	− 0.02 (− 0.11, 0.07)

Voice Handicap Index (VHI) ranges from 0 to 120; PDQ-39 summary index and communication domain score range from 0 to 100, where low score is good
EQ-5D-3L ranges from -0.59 to 1; ICECAP-O from 0 to 1, where high score is good
^aReference group: H&Y 2.5 and above
^bReference group: yes response
^*p < 0.01

ISSN: 2055-5784