Table 3 Study primary and secondary endpoints. Data are expressed as mean (SD), unless otherwise specified
Variable | FEIBA n = 6 | Placebo n = 6 | Difference (95% confidence interval) |
|---|---|---|---|
Volume of all blood products transfused, mL | 3126 (3710) | 2227 (3710) | −899 (−5205.7 to 3408.7) |
Blood product transfused intraoperatively | |||
Packed red blood cells, n (%) | 4 (67) | 0 (0) | |
Packed red blood cells, mL | 572 (552) | 0 (0) | −572 (−1073.7 to −69.6) |
Fresh-frozen plasma, n (%) | 4 (67) | 4 (67) | |
Fresh-frozen plasma, mL | 981 (857) | 338 (288) | −643 (−1465.2 to 179.2) |
Platelets, n (%) | 6 (100) | 5 (83) | |
Platelets, mL | 952 (511) | 437 (308) | −515 (−1057.2 to 27.2) |
Cryoprecipitate, n (%) | 3 (50) | 0 (0) | |
Cryoprecipitate, mL | 171 (210) | 0 | −171 (−362.2 to 20.2) |
Blood product transfused in the ICU | |||
Packed red blood cells, n (%) | 1 (17) | 1 (17) | |
Packed red blood cells, mL | 175 (429) | 572 (1400) | 397 (−935.4 to 1728.8) |
Fresh-frozen plasma, n (%) | 1 (17) | 1 (17) | |
Fresh-frozen plasma, mL | 102 (250) | 437 (1070) | 335 (−664.7 to 1333.7) |
Platelets, n (%) | 1 (17) | 1 (17) | |
Platelets, mL | 49 (119) | 83 (204) | 35 (−179.8 to 249.2) |
Cryoprecipitate, n (%) | 1 (17) | 1 (17) | |
Cryoprecipitate, mL | 21 (51) | 79 (194) | 58 (−123.9 to 240.2) |
Patients requiring re-exploration, n (%) | 1 (17) | 1 (17) | |
Chest tube drainage at 8 h, mL | 282 (110) | 611 (860) | 329 (−459.3 to 1117.3) |
Chest tube drainage at 24 h, mL | 725 (559) | 913 (1028) | 188 (−876.1 to 1252.4) |
ICU intubation, hours | 87.2 (162.6) | 8.2 (6.2) | −79 (−249.6 to 91.6) |
Length of ICU stay, hours | 333.5 (670.7) | 74.3 (51.1) | 259.2 (−962.7 to 444.4) |
Length of hospital stay, days | 20.3 (25.7) | 5.7 (1.0) | 14.7 (−41.6 to 12.3) |