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Table 3 Side effects and re-consultation

From: Diarrhoea Management using Over-the-counter Nutraceuticals in Daily practice (DIAMOND): a feasibility RCT on alternative therapy to reduce antibiotic use

 

Number analysed

Group A

Loperamide alone

Group B

Loperamide and berberine

Group C

Loperamide and turmeric

Group D

Loperamide and turmeric and berberine

Mean severity of constipationa at 24 h (mean, sd)

12

1.3 (0.6)

-

-

0.8 (0.4)

Mean severity of constipation at 48 h (mean, sd)

6

1.0 (1.0)

-

-

1.0 (1.4)

Re-consultation (n, %)

125

1 (3.6)

1 (2.9)

0 (0.0)

1 (3.3)

Re-contact (n, %)

125

1 (3.6)

1 (2.9)

1 (3.0)

(0.0)

  1. aConstipation severity rated on a scale from 0 to 6, where 0 indicates no problem, 1 indicates ‘very little problem’, 2 indicates ‘slight problem’, 3 indicates ‘moderately bad’, 4 indicates ‘bad’, 5 indicates ‘very bad’ and 6 indicates ‘as bad as it could be’