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Table 1 Baseline characteristics

From: Diarrhoea Management using Over-the-counter Nutraceuticals in Daily practice (DIAMOND): a feasibility RCT on alternative therapy to reduce antibiotic use

 

Number

Group A

Loperamide only

(N=34)

Group B

Loperamide and berberine

(N=34)

Group C

Loperamide and turmeric (N=34)

Group D

Loperamide, turmeric and berberine

(N=34)

Gender—male (n, %)

136

18 (52.9)

20 (58.8)

17 (50.0)

22 (64.7)

Age (mean, sd)

134

33.0 (10.2)

29.9 (10.7)

34.7 (12.3)

34.0 (13.1)

Hometown—from Shanghai

136

13 (38.2)

11 (32.4)

16 (47.1)

13 (38.2)

Number loose stools in last 24 h (median, IQR)

134

4.5 (4, 5)

4 (3.5, 5.5)

4 (3, 5)

4 (3.5, 6)

Mean symptom severitya (mean, sd)

128

0.9 (0.5)

1.3 (0.8)

1.1 (0.7)

1.1 (0.7)

Prior duration of loose stools (median, IQR)

127

19 (8, 35)

13.5 (9, 28)

13 (9, 33)

18 (11, 30)

  1. aSymptoms (nausea, vomiting, abdominal cramping, generally unwell, fever, muscle ache, headache, disturbed sleep, interference with normal activities, interference with social activities, diarrhoea) rated on a scale from 0 to 6, where 0 indicates no problem, 1 indicates ‘very little problem’, 2 indicates ‘slight problem’, 3 indicates ‘moderately bad’, 4 indicates ‘bad’, 5 indicates ‘very bad’ and 6 indicates ‘as bad as it could be’