Standard care informed by the result of a placental growth factor blood test versus standard care alone in women with reduced fetal movement at or after 36+0 weeks’ gestation: a pilot randomised controlled trial

Table 2 Compliance with allocated trial intervention

	Control (n = 107)	Intervention (n = 109)
Trial blood sample taken	107 (100%)	109 (100%)
Blood sample analysed at site
Yes	0 (–)	109 (100%)
No	107 (100%)	0 (–)
sFlt-1/PlGF ratio obtained by site and revealed to participant	–	109 (100%)
Test result (sFlt-1/PlGF ratio)	–
Mean (SD)	–	21.1 (23.9)
Median (25th, 75th centile)	–	14.8 (5.3, 27.8)
Min, max	–	0.6, 151.1
Expedited delivery offered		sFlt-1/PlGF ratio < 38 (n = 93)	sFlt-1/PlGF ratio ≥ 38 (n = 16)
Yes	9 (8%)	8¹ (9%)	15 (94%)
No	98 (92%)	85 (91%)	1² (6%)
Expedited delivery accepted
Yes	9 (100%)	8 (100%)	12 (80%)
No	0 (–)	0 (–)	3³ (20%)

All data are N (%) unless indicated
¹Reasons for offering expedited delivery in the intervention arm with sFlt-1/PlGF ratio < 38 include the following: participant wanted induction of labour even though not indicated (n = 2), clinician decision to deliver baby (n = 5) and participant offered induction for recurrent RFM (n = 1)
²Reasons for not offering expedited delivery in the intervention arm with sFlt-1/PlGF ≥ 38 include the following: clinician decision to continue pregnancy (n = 1)
³Reasons for not accepting expedited delivery in the intervention arm with sFlt-1/PlGF ≥ 38 include the following: would like delivery on midwife-led unit, feels well and baby at the time was moving well (n = 1); discussed results with husband and decided not to accept expedited delivery (n = 1); induction date booked in 1 weeks’ time, would like to stay with that plan (n = 1)

ISSN: 2055-5784