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Table 2 Compliance with allocated trial intervention

From: Standard care informed by the result of a placental growth factor blood test versus standard care alone in women with reduced fetal movement at or after 36+0 weeks’ gestation: a pilot randomised controlled trial

 Control (n = 107)Intervention (n = 109)
Trial blood sample taken107 (100%)109 (100%)
Blood sample analysed at site
 Yes0 (–)109 (100%)
 No107 (100%)0 (–)
sFlt-1/PlGF ratio obtained by site and revealed to participant–109 (100%)
Test result (sFlt-1/PlGF ratio)– 
 Mean (SD)–21.1 (23.9)
 Median (25th, 75th centile)–14.8 (5.3, 27.8)
 Min, max–0.6, 151.1
Expedited delivery offered sFlt-1/PlGF ratio < 38 (n = 93)sFlt-1/PlGF ratio ≥ 38 (n = 16)
 Yes9 (8%)81 (9%)15 (94%)
 No98 (92%)85 (91%)12 (6%)
Expedited delivery accepted
 Yes9 (100%)8 (100%)12 (80%)
 No0 (–)0 (–)33 (20%)
  1. All data are N (%) unless indicated
  2. 1Reasons for offering expedited delivery in the intervention arm with sFlt-1/PlGF ratio < 38 include the following: participant wanted induction of labour even though not indicated (n = 2), clinician decision to deliver baby (n = 5) and participant offered induction for recurrent RFM (n = 1)
  3. 2Reasons for not offering expedited delivery in the intervention arm with sFlt-1/PlGF ≥ 38 include the following: clinician decision to continue pregnancy (n = 1)
  4. 3Reasons for not accepting expedited delivery in the intervention arm with sFlt-1/PlGF ≥ 38 include the following: would like delivery on midwife-led unit, feels well and baby at the time was moving well (n = 1); discussed results with husband and decided not to accept expedited delivery (n = 1); induction date booked in 1 weeks’ time, would like to stay with that plan (n = 1)
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Pilot and Feasibility Studies

ISSN: 2055-5784