Skip to main content

Table 1 Baseline characteristics

From: Standard care informed by the result of a placental growth factor blood test versus standard care alone in women with reduced fetal movement at or after 36+0 weeks’ gestation: a pilot randomised controlled trial

CharacteristicControl (n = 107)Intervention (n = 109)Total (n = 216)
Maternal age (years)
 Mean (SD)29.2 (5.7)30.4 (5.4)29.8 (5.6)
Gestational age at randomisation (weeks)
 Mean (SD)37.8 (1.2)37.9 (1.4)37.9 (1.3)
Stratification variable
  ≥ 40+07 (7%)10 (9%)17 (8%)
Ethnicity
 White93 (87%)93 (85%)186 (86%)
 Black1 (1%)5 (5%)6 (3%)
 South Asian7 (7%)6 (6%)13 (6%)
 East Asian3 (3%)3 (3%)6 (3%)
 Mixed Race1 (1%)2 (2%)3 (1%)
 Others2 (2%)0 (–)2 (1%)
BMI at booking visit
 Mean (SD)26.8 (5.6)27.4 (6.3)27.1 (6.0)
Parity
 048 (45%)53 (49%)101 (47%)
 137 (35%)36 (33%)73 (34%)
 ≥ 222 (20%)20 (18%)42 (19%)
Number of previous stillbirths
 11 (1%)1 (1%)2 (1%)
Obstetric history for previous pregnancies1
 Yes23 (21%)19 (17%)42 (19%)
Obstetric cholestasis0 (–)4 (4%)4 (2%)
Placental abruption2 (2%)1 (1%)3 (1%)
Preeclampsia5 (5%)1 (1%)6 (3%)
SGA baby5 (5%)2 (2%)7 (3%)
Other16 (15%)14 (13%)30 (14%)
Diagnoses in current pregnancy1
 Antepartum haemorrhage0 (–)1 (1%)1 (< 1%)
 Hypertension1 (1%)1 (1%)2 (1%)
 Obstetric cholestasis0 (0%)2 (2%)2 (1%)
 Other26 (6%)4 (4%)10 (5%)
Past medical history115 (14%)12 (11%)27 (13%)
 Hypertension4 (4%)0 (–)4 (2%)
 Diabetes2 (2%)0 (–)2 (1%)
 Other310 (9%)12 (11%)22 (10%)
Estimated fetal weight from ultrasound scan (g)
 Mean (SD)3255 (520.6)3109 (500.1)3181 (514.4)
Centile usingINTERGROWTH-21stbirthweight standard
 Mean (SD)67.4 (24.7)59.1 (25.8)63.3 (25.6)
 SGA fetus3 (3%)5 (5%)8 (4%)
Prescribed medication at the trial entry1
 Aspirin8 (7%)7 (6%)15 (7%)
 Other410 (9%)11 (10%)21 (10%)
Substance misuse during this pregnancy
 Benzodiazepine0 (–)3 (3%)3 (1%)
Cigarette smoking status during this pregnancy
 Currently smoking5 (5%)3 (3%)8 (4%)
 Stopped smoking in this pregnancy5 (5%)4 (4%)9 (4%)
 Not smoked in this pregnancy97 (91%)102 (94%)199 (92%)
Duration women concerned about baby’s movements (h)
 0–2476 (71%)72 (66%)148 (69%)
 25–489 (8%)18 (17%)27 (13%)
 > 4822 (21%)19 (17%)41 (19%)
Absent fetal movements
 Yes37 (35%)51 (47%)88 (41%)
 No70 (65%)58 (53%)128 (59%)
  1. All data are N (%) unless indicated
  2. 1Categories are not mutually exclusive
  3. 2Others include anxiety and depression (n = 2), gestational diabetes, placenta praevia, medullary sponge kidney, hypothyroidism, gallstones/pancreatitis, type 1 diabetes, GBS, thrush and fibromyalgia (not mutually exclusive)
  4. 3Others include significant cardiac disease (n = 3), significant gastrointestinal problems (n = 3), significant mental health problems (n = 10), renal disease (n = 1) and thyroid disease (n = 7)
  5. 4Others include antidepressants (n = 14), benzodiazepines (n = 3) and low molecular weight heparin (n = 6)