Characteristic | Control (n = 107) | Intervention (n = 109) | Total (n = 216) |
---|---|---|---|
Maternal age (years) | |||
Mean (SD) | 29.2 (5.7) | 30.4 (5.4) | 29.8 (5.6) |
Gestational age at randomisation (weeks) | |||
Mean (SD) | 37.8 (1.2) | 37.9 (1.4) | 37.9 (1.3) |
Stratification variable | |||
≥ 40+0 | 7 (7%) | 10 (9%) | 17 (8%) |
Ethnicity | |||
White | 93 (87%) | 93 (85%) | 186 (86%) |
Black | 1 (1%) | 5 (5%) | 6 (3%) |
South Asian | 7 (7%) | 6 (6%) | 13 (6%) |
East Asian | 3 (3%) | 3 (3%) | 6 (3%) |
Mixed Race | 1 (1%) | 2 (2%) | 3 (1%) |
Others | 2 (2%) | 0 (–) | 2 (1%) |
BMI at booking visit | |||
Mean (SD) | 26.8 (5.6) | 27.4 (6.3) | 27.1 (6.0) |
Parity | |||
0 | 48 (45%) | 53 (49%) | 101 (47%) |
1 | 37 (35%) | 36 (33%) | 73 (34%) |
≥ 2 | 22 (20%) | 20 (18%) | 42 (19%) |
Number of previous stillbirths | |||
1 | 1 (1%) | 1 (1%) | 2 (1%) |
Obstetric history for previous pregnancies1 | |||
Yes | 23 (21%) | 19 (17%) | 42 (19%) |
Obstetric cholestasis | 0 (–) | 4 (4%) | 4 (2%) |
Placental abruption | 2 (2%) | 1 (1%) | 3 (1%) |
Preeclampsia | 5 (5%) | 1 (1%) | 6 (3%) |
SGA baby | 5 (5%) | 2 (2%) | 7 (3%) |
Other | 16 (15%) | 14 (13%) | 30 (14%) |
Diagnoses in current pregnancy1 | |||
Antepartum haemorrhage | 0 (–) | 1 (1%) | 1 (< 1%) |
Hypertension | 1 (1%) | 1 (1%) | 2 (1%) |
Obstetric cholestasis | 0 (0%) | 2 (2%) | 2 (1%) |
Other2 | 6 (6%) | 4 (4%) | 10 (5%) |
Past medical history1 | 15 (14%) | 12 (11%) | 27 (13%) |
Hypertension | 4 (4%) | 0 (–) | 4 (2%) |
Diabetes | 2 (2%) | 0 (–) | 2 (1%) |
Other3 | 10 (9%) | 12 (11%) | 22 (10%) |
Estimated fetal weight from ultrasound scan (g) | |||
Mean (SD) | 3255 (520.6) | 3109 (500.1) | 3181 (514.4) |
Centile usingINTERGROWTH-21stbirthweight standard | |||
Mean (SD) | 67.4 (24.7) | 59.1 (25.8) | 63.3 (25.6) |
SGA fetus | 3 (3%) | 5 (5%) | 8 (4%) |
Prescribed medication at the trial entry1 | |||
Aspirin | 8 (7%) | 7 (6%) | 15 (7%) |
Other4 | 10 (9%) | 11 (10%) | 21 (10%) |
Substance misuse during this pregnancy | |||
Benzodiazepine | 0 (–) | 3 (3%) | 3 (1%) |
Cigarette smoking status during this pregnancy | |||
Currently smoking | 5 (5%) | 3 (3%) | 8 (4%) |
Stopped smoking in this pregnancy | 5 (5%) | 4 (4%) | 9 (4%) |
Not smoked in this pregnancy | 97 (91%) | 102 (94%) | 199 (92%) |
Duration women concerned about baby’s movements (h) | |||
0–24 | 76 (71%) | 72 (66%) | 148 (69%) |
25–48 | 9 (8%) | 18 (17%) | 27 (13%) |
> 48 | 22 (21%) | 19 (17%) | 41 (19%) |
Absent fetal movements | |||
Yes | 37 (35%) | 51 (47%) | 88 (41%) |
No | 70 (65%) | 58 (53%) | 128 (59%) |