| Control | Intervention | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
 | Baseline, mean (SD) | 3 months, mean (SD) | 6 months, mean (SD) | Mean difference (95% CI): baseline to 3 months | Mean difference (95% CI): baseline to 6 months | Baseline, mean (SD) | 3 months, mean (SD) | 6 months, mean (SD) | Mean difference (95% CI): baseline to 3 months | Mean difference (95% CI): baseline to 6 months |
Current symptoms from inflammatory condition | ||||||||||
 Pain (0–10 NRS) | 5.1 (2.7) | 4.8 (2.7) | 4.8 (2.6) | − 0.22 (− 0.51, 0.06) | − 0.30 (− 0.62, 0.02) | 4.7 (2.6) | 4.5 (2.7) | 4.6 (2.6) | − 0.13 (− 0.38, 0.12) | − 0.09 (− 0.35, 0.16) |
 Stiffness (0–10 NRS) | 5.4 (2.7) | 5.1 (2.6) | 5.1 (2.7) | − 0.26 (− 0.53, 0.02) | − 0.25 (− 0.56, 0.05) | 4.7 (2.5) | 4.7 (2.6) | 4.6 (2.6) | 0.06 (− 0.18, 0.29) | − 0.13 (− 0.41, 0.16) |
 Fatigue (0–10 NRS) | 5.4 (2.7) | 5.1 (2.6) | 5.0 (2.6) | − 0.27 (− 0.57, 0.02) | − 0.39 (− 0.67, − 0.10) | 5.0 (2.8) | 4.9 (2.8) | 4.9 (2.7) | − 0.19 (− 0.44, 0.06) | − 0.13 (− 0.42, 0.15) |
Self-Efficacy for Managing Chronic Diseasea | 5.8 (2.5) | NA | 6.1 (2.5) | NA | 0.25 (− 0.02, 0.51) | 6.0 (2.5) | NA | 6.1 (2.5) | NA | 0.11 (− 0.13, 0.35) |
EQ-5D totalb | 10.96 (3.69) | 10.83 (4.00) | 10.60 (3.75) | − 0.17 (− 0.46, 0.12) | − 0.38 (− 0.70, − 0.06) | 10.69 (3.62) | 10.67 (3.60) | 10.72 (3.82) | − 0.01 (− 0.35, 0.32) | 0.03 (− 0.29, 0.35) |
FACIT-Fatiguec | 33.5 (11.5) | NA | 27.9 (10.2) | NA | − 5.77 (− 6.75, − 4.79) | 32.7 (11.8) | NA | 27.6 (10.4) | NA | − 5.01 (− 5.98, − 4.05) |
 | Median (IQR) | Median (IQR) | Median (IQR) | Median difference (IQR): baseline to 3 months | Median difference (IQR): baseline to 3 months | Median (IQR) | Median (IQR) | Median (IQR) | Median difference (IQR): baseline to 3 months | Median difference (IQR): baseline to 3 months |
Multimorbidity Treatment Burden Questionnaire (MTBQ)d | 7.5 (2.5, 17.5) | 7.5 (2.5, 20) | 7.5 (2.5, 20) | 0 (0, 5) | 0 (− 2.5, 5.0) | 7.5 (2.5, 20) | 10 (2.5, 22.5) | 10 (2.5, 20) | 0 (− 2.5, 2.5) | 0 (− 2.5, 2.5) |
Modified Health Assessment Questionnaire (MHAQ)e | 0.38 (0, 0.88) | NA | 0.38 (0.13, 0.38) | NA | 0 (− 0.13, 0.13) | 0.38 (0.13, 0.88) | NA | 0.38 (0, 0.88) | NA | 0 (− 0.13, 0) |