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Table 1 Needs analysis by COM-B and TDF with decisions for inclusion/exclusion in the intervention

From: Development of an intervention to increase adherence to nebuliser treatment in adults with cystic fibrosis: CFHealthHub

COM-B component

TDF domain

Needs analysis

Inclusion/exclusion

Physical capability

Physical skills

Need skills to use nebuliser, prepare treatment, and clean nebuliser

Included

Psychological capability

Knowledge

Need to know about the correct treatment-taking procedures, to understand treatment action and the importance of nebuliser treatment

Need to address treatment concerns

Included

Memory, attention, and decision processes

Need to remember to take treatment

Included

Behavioural regulation

Need to develop routines, plans, and habits for treatment

Need to monitor adherence behaviour

Included

Physical opportunity

Environmental context and resources

Need to have a time, place, and the equipment do take treatment

Need to develop strategies to take treatment around specific barriers or times when treatment taking is more difficult

Included

Social opportunity

Social influences

Need positive support from family, healthcare professionals, and/or others to do treatment

Need to have social norms for adherence

Included

Reflective motivation

Professional/social role and identity

Need to develop a social identify that is consistent with treatment adherence

Excluded—social identity change in the context of adherence is not well understood

Beliefs about capabilities

Need to develop confidence in the ability to take and adhere to treatment

Need to develop strategies to take treatment at times or in situations when it is more difficult

Included

Optimism

Need to be optimistic that full treatment adherence is possible

Excluded—focus on achieving higher but realistic adherence

Beliefs about consequences

Need to believe that treatment is effective and necessary for long-term health, symptom reduction, avoiding IVs/hospital stays

Need to believe that treatment is important irrelevant of perceptions of current wellness

Need to address treatment concerns

Included

Intentions

Need to encourage intentions to adhere to treatment and avoid periods of intentional non-adherence

Included

Goals

Need goals for treatment adherence

Need to develop strategies to address conflicting goals

Included

Automatic motivation

Reinforcement

Need to provide some reinforcement for treatment-taking

Need to address treatment concerns

Included

Emotion

Need to focus on emotional drivers for adherence (fear, anticipated regret)

Need to address low mood and avoidance

Excluded—not acceptable to focus on fear and may increase avoidance. Addressing low mood/depression outside the scope of this intervention (signposting to other support services)