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Table 1 Demographics

From: Agitation, confusion, and aggression in critically ill traumatic brain injury-a pilot cohort study (ACACIA-PILOT)

Demographics

Agitation

N = 17

No agitation

N = 13

All patients

N = 30

Median age, years (IQR)

60 (46.5)

66.0 (39)

64.5 (41.3)

Median APACHE 2 (IQR)

16.0 (9.0)

17.0 (10.5)

16.5 (9.25)

Median Injury Severity Score (IQR)

26.0 (14.0)

22.0 (26.5)

26.0 (18.0)

ICU admission GCS

6.0 (IQR 4.5)

13.0 (IQR 11.5)

6.0 (10.3)

Male sex

15 (88.2%)*

7 (53.8%)

22 (73.3%)

Primary language at home

 French

13 (76.4%)

12 (92.3%)

25 (83.3%)

 English

1 (5.9%)

1 (7.7%)

2 (6.7%)

 Other

3 (17.6%)

0

3 (10.0%)

Highest education level completed

 Primary

5 (29.4%)

3 (23.1%)

8 (25.8%)

 Secondary

10 (58.8%)

7 (53.8%)

16 (51.6%)

 University

2 (11.8%)

3 (23.1%)

5 (16.1%)

TBI severity

 Severe

4 (23.5%)

5 (38.5%)

9 (30.0%)

 Moderate

11 (64.7%)

2 (15.4%)

13 (43.3%)

 Mild complex

2 (11.8%)

6 (46.2%)

8 (26.7%)

TBI mechanism

 Falls

9 (52.9%)

6 (46.2%)

15 (50%)

 MVA

7 (41.2%)

6 (46.2%)

13 (43%)

 Other

1 (7.7%)

1 (5.9%)

2 (7%)

Localization of lesions

 No lesions

1 (5.9%)

2 (15.4%)

3 (10%)

 Frontal

8 (47.1%)

3 (23.1%)

11 (36.7%)

 Temporal

0 (0%)

1 (7.7%)

1 (3.3%)

 Fronto-temporal

5 (29.4%)

7 (53.8%)

12 (40%)

 Parieto-occipital

10 (58.8%)

4 (30.8%)

14 (46.7%)

Marshall score, median (range)

2 (1-6)

1 (1-5)

1.5 (1-6)

Rotterdam score, median (range)

3 (1-5)

3 (2-6)

3 (1-6)

Hearing impairment

3 (17.6%)

2 (15.4%)

5 (16.7%)

Attention deficit hyperactivity disorder

4 (23.5%)

0

4 (13.3%)

Ethanol positive screening on admission

4 (23.5%)

3 (23.1%)

7 (23.3%)

Active alcohol use

2 (11.8%)

0

2 (6.7%)

Active drug use (< 7 days)*

5 (29.4%)

0

5 (16.7%)

Active smoking

6 (35.3%)

4 (30.8%)

10 (33.3%)

  1. Data are presented as median (IQR), or N (%) unless otherwise stated. *P < 0.05; other comparisons are non-significant
  2. APACHE Acute Physiology and Chronic Health Evaluation, ICU intensive care unit, IQR interquartile range, GCS Glasgow Coma Scale, MVA motor vehicle accident, TBI traumatic brain injury